Clinical trials: Emergency Departments
VV-ECMO, Thoracic Surgery
Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery
Veno-vneous extracorporeal membrane oxygenation (VV-ECMO) is an established support strategy for acute respiratory failure, but its role in the perioperative management of emergency thoracic surgery remains poorly defined.
- Conditions
- VV-ECMO, Thoracic Surgery, Emergency Surgery, ARDS
- Trial name
- PECUR (NCT07016685)
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Urinary Tract Infections
Does Implementing a Urinanylsis Protocol Based on Symptoms Decrease Length of Stay in the Emergency Department?
The implementation of nursing urinanlysis protocols based off of symptoms of urinary infections will significantly decrease the length of a patient's stay in the Emergency Department.
- Trial name
- NCT00583648
- Testing
- Urinanlysis
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Dyspnea
BRIPPED Scan for Evaluation of Emergency Department (ED) Patients With Shortness of Breath
The B-RIPPED scan is a standardized ultrasound evaluation of pulmonary B-lines, Right ventricle size and strain, Inferior Vena Cava collapsibility, Pleural and Pericardial Effusion, Pneumothorax, Ejection Fraction, and lower…
- Trial name
- BRIPPED (NCT01662843)
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Epilepsy
Epidemiology of Suspected Epileptic Seizures
The occurrence of isolated or recurring epileptic seizures accounts for an important use of the healthcare system. Typically, epileptic patient will consult ten times a year a physician (specialist or familial doctor) and will…
- Trial name
- EPI-lepsie (NCT04147663)
- Testing
- describe the management of the adult population suffering from suspected seizure by the emergency structures
- Where
- France
- Volunteers
- 2,300 people
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
Asthma
Randomised Controlled Trial of a Multi-faceted Community-based Intervention to Improve Asthma in Children
The objectives of this trials are to demonstrate, in children with poorly controlled asthma, that an intervention to increase the awareness and the impact of poor asthma control among parents and physicians of affected children…
- Trial name
- NCT00238888
- Testing
- asthma control awareness, Usual care
- Where
- Canada
- Volunteers
- 298 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hemorrhage
Finnish Prehospital Whole Blood Study
Up-to-date evidence suggests that blood transfusion initiated as early as possible reduces the likelihood of death from hemorrhagic shock, and the sooner replacement therapy with blood products is initiated, the greater the…
- Trial name
- FinnPHWB (NCT05744583)
- Testing
- Packed red cell transfusion, Whole blood transfusion
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Finnish Red Cross Blood Service
Myocardial Injury After Non-cardiac Surgery, Abdomen, Acute
Troponin I Level and Mortality in Acute Abdominal Surgery
The goal of this prospective cohort study is to estimate the incidence of myocardial injury after non-cardiac surgery (MINS) in patients undergoing acute high-risk abdominal surgery.
- Trial name
- NCT05933837
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Nordsjaellands Hospital
Vaccination/Immunisation Status
Vaccination Coverage Amongst Children/Young People Attending the PED
In the United Kingdom (UK), most childhood vaccinations are given in the community, although uptake has decreased in recent years.
- Trial name
- NCT04485624
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 2,693 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Cardiac Arrest, Cardiopulmonary Arrest
Continuous Compressions With Asynchronous Ventilations Using I-gel Device Versus 30:2 Approach During Simulated OHCA
Paramedics and EMT will be recruited among four Emergency Medical Services (EMS) in Switzerland to manage a 10-minutes simulation-based adult out-of-hospital cardiac arrest scenario in teams of two.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Emergency Medical Services, Resuscitation
- Trial name
- NCT04736446
- Testing
- I-gel® supraglottic device, Face mask ventilation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Geneve TEAM Ambulances
Shock
Diagnostic Investigation and Prediction of Shock
Background to the research Patients present to Emergency Departments (ED) with a spectrum of illness, many of which are life- threatening.
- Trial name
- DiPS (NCT03043170)
- Testing
- Ultrasound Cardiac Output Monitor
- Where
- United Kingdom
- Volunteers
- 361 people
- Sponsor
- Cardiff University
Social Determinants of Health
Social Needs Screenings in ED
This study will determine whether existing Health Information Technology can be leveraged to 1) implement a universal, patient-centered social needs assessment and referral process during routine Emergency Department care; 2)…
- Trial name
- NCT04630041
- Testing
- 211 Referral
- Where
- United States
- Volunteers
- 5,081 people
- Sponsor
- Andrea Wallace
Echocardiography, Medicine, Emergency
Evaluation of LVEF by a New Automatic Evaluation Tool in a Pocket Ultrasound Scanner
Clinical ultrasound has become essential in emergency medicine. The guidelines are to use of echocardiography in specific contexts: dyspnea, hypotension or chest pain.
- Conditions
- Echocardiography, Medicine, Emergency, Technology Assessment, Biomedical, Heart Diseases
- Trial name
- ReproAuto_FEVG (NCT04366453)
- Testing
- echocardiography
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Emergency Medicine
Assessing Mixed Reality for Emergency Medical Care Delivery in a Simulated Environment
This study assessed the feasibility and effectiveness of using Mixed Reality (MR) through the use of HoloLens2TM technology to enhance emergency clinical care delivery in a simulated environment.
- Trial name
- NCT05870137
- Testing
- HoloLens2TM, Standard care
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Imperial College London
Acute Respiratory Failure
A Check-list Including Lung Ultrasound for ED Patients With ARF
The aim of the study is to evaluate if a check-list including lung ultrasonography can help to identify the etiology of the acute respiratory failure of patients managed at the emergency room.
- Trial name
- CHECKIRA-COVID (NCT04791241)
- Testing
- check-list including lung ultrasound
- Where
- 3 sites in France
- Volunteers
- 105 people
- Sponsor
- Centre Hospitalier Metropole Savoie
Vertigo, Dizziness
Prospective Registry of Vertigo Due to Vertebrobasilar Transient Attacks.
Vertigo and dizziness are common neurological complaints in the emergency department and may represent a wide spectrum of etiologies, including vertebrobasilar transient neurological attacks (VB-TNAs).
- Conditions
- Vertigo, Dizziness, TIA (Transient Ischemic Attack), Transient Neurologic Symptoms
- Trial name
- UTRAVERA (NCT07421973)
- Where
- Brazil
- Volunteers
- 400 people
- Sponsor
- University of Sao Paulo General Hospital
Kidney Stone
Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis
Tamsulosin (Flowmax)is approved by the FDA for the treatment for enlarged prostate. Several studies regarding the use of Tamsulosin for the treatment of lower kidney stones have been carried out in the non-Emergency Department…
- Trial name
- Flowmax (NCT00762424)
- Testing
- Flowmax
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- WellSpan Health
Smoking Cessation, Smoking
The SmokeFree App Smoking Cessation Study
SmokeFree is a theory-driven and evidence-based stop smoking mobile application. Based on NICE guidance and best practice for smoking cessation, the application employs over 30 behaviour change techniques used in NHS Stop Smoking…
- Conditions
- Smoking Cessation, Smoking, Smoking Reduction, Smoking Habit
- Trial name
- SMOKEFREE (NCT05094583)
- Testing
- Use of SmokeFree app
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Prevention
Effect of Implementing Prevention Measures Through Personalized Information in Emergency Departments on Adherence to Prevention Measures
Prevention, a cornerstone of public health, remains underutilized despite its proven effectiveness. Vaccinations, screenings, reduced consumption of toxic substances, and healthy lifestyle and dietary habits can significantly…
- Trial name
- PREV-URG (NCT07714460)
- Testing
- personalized preventive health information, non-personalized preventive health information
- Where
- 2 sites in France
- Volunteers
- 658 people
- Sponsor
- Centre Hospitalier le Mans
Suicidal, Suicidal Ideation
Intramuscular Ketamine for Suicidal Patients in the Evanston Hospital Emergency Department for Suicidal Distress
This pilot study aims to evaluate the feasibility and acceptability of administering intramuscular ketamine for the acute reduction of suicidal distress during psychiatric boarding at the Evanston Hospital ED.
- Conditions
- Suicidal, Suicidal Ideation, Suicidal Ideation and Behavior, Depression / Major Depressive Disorder
- Trial name
- KEDS-C (NCT07810023)
- Testing
- Ketamine (0.5 mg/kg)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Endeavor Health
Out-of-Hospital Cardiac Arrest
Reduction of Oxygen After Cardiac Arrest
The Reduction of oxygen after cardiac arrest (EXACT) is a multi-centre, randomised, controlled trial (RCT) to determine whether reducing oxygen administration to target an oxygen saturation of 90-94%, compared to 98-100%, as soon…
- Trial name
- EXACT (NCT03138005)
- Testing
- target SpO2 98-100%, target SpO2 90-94%
- Where
- 21 sites in Australia
- Volunteers
- 428 people
- Sponsor
- Monash University
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