Clinical trials: Emergency Surgery Patients
Surgical Site Infection
Tracking Wound Infection With Smartphone Technology
This study aims to evaluate if a smartphone-delivered tool can help assess for wound infections, and if this improves access to care and results in earlier treatment. Participants will be randomised to one of two groups.
- Trial name
- TWIST (NCT02704897)
- Testing
- Wound Assessment Tool
- Where
- 2 sites in United Kingdom
- Volunteers
- 492 people
- Sponsor
- University of Edinburgh
One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems
A Comparative Study of CCI, EmSFI, and FTRST Scoring Systems
Frailty assessment tools and comorbidity indices play a crucial role, particularly in predicting outcomes for elderly patients undergoing emergency surgery.
- Conditions
- One Hundred Patients Aged 65 and Older Who Underwent Emergency General Surgical Interventions, Clinical Utility of These Scoring Systems, Gastrointestinal Neoplasms, Appendicitis Acute
- Trial name
- NCT06943924
- Testing
- Frailty assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Sleep Disorder
Association Between Preoperative Insomnia and Postoperative Quality of Recovery : A Prospective Observational Study
Although patients with cancers are prone to insomnia, especially waiting for surgery during hospitalization, and insomnia promotes acute respiratory infections (ARI) and is not conducive to the postoperative quality of recovery…
- Trial name
- PIPQoR (NCT06008873)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment
Effect and Safety of Surgical Intervention for Severe Spontaneous Intracerebral Hemorrhage Patients on Long-term Oral Antiplatelet Treatment
Background: Despite the capability of emergency surgery to reduce the mortality of severe spontaneous intracranial hemorrhage (SSICH) patients, the effect and safety of surgical treatment for severe spontaneous intracranial…
- Conditions
- Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, Complications
- Trial name
- NCT05766865
- Testing
- Emergency neurosurgery, Conservative treatment
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Beijing Tiantan Hospital
Perforated Duodenal Ulcer
Early Oral Feeding vs Traditional Post-operative Care In Emergency Abdominal Surgeries
ABSTRACT BACKGROUND: Enhanced recovery after surgery (ERAS) protocols have been widely studied in elective abdominal surgeries and have shown better outcomes.
- Trial name
- NCT04431037
- Testing
- Early oral feeding/Enhanced recovery after surgery protocols
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- College of Physicians and Surgeons Pakistan
Hip Fractures, Elderly
Patient Reported Experience Measures Following Hip Fracture Surgery in the Elderly
With an ageing population, hip fractures are likely to become a significant public health burden. Hip fracture surgery is associated with significant morbidity and mortality.
- Conditions
- Hip Fractures, Elderly, Emergency Surgery
- Trial name
- NCT02842996
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Frailty, Surgery
Retrospective Analysis of Sarcopenia in Older Patients Undergoing Laparotomy
Assess the influence of sarcopenia on outcomes of emergency laparotomy in the over 65 age group
- Conditions
- Frailty, Surgery, Emergencies
- Trial name
- NCT04493710
- Testing
- Sarcopenia estimation
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Splenic Abscess, Sarcopenia
Sarcopaenia is a Useful Risk Stratification Tool for Surgeons to Prognosticate Splenic Abscess Patients
Sarcopaenia is associated with poor prognoses of in-hospital mortality in splenic abscess patients. Investigators recommend its use by surgeons in the ED to rapidly risk stratify and identify patients requiring urgent and…
- Trial name
- NCT03967041
- Testing
- radiological defined sarcopenia
- Where
- Taiwan
- Volunteers
- 99 people
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Death
Descriptive and Risk Factors Analysis of All-cause Postoperative Death in Patients Undergoing Emergency Surgery
The investigators are aimed to develop and externally validate a prediction model of clinical risk factors that quantifies postoperative death after emergency surgery.
- Trial name
- NCT04926038
- Where
- 5 sites in China
- Volunteers
- 200,000 people
- Sponsor
- Huazhong University of Science and Technology
Sepsis, Intra-Abdominal Infections
Gelaspan vs Crystalloid Therapy in Sepsis
The goal of this randomized clinical trial is to evaluate whether balanced gelatin solution is more effective and safe than balanced crystalloid solution for perioperative fluid management in adults with sepsis undergoing…
- Trial name
- SPACES (NCT07172451)
- Testing
- Balanced Gelatin Solution, Acetate Ringer's Solution
- Where
- 9 sites in China
- Volunteers
- 318 people
- Sponsor
- Shanghai Zhongshan Hospital
The Focus of Study is to Elucidate Which Are the Factors Requiring the Duodenostomy and Which Postoperative Course is for These Patients
Duodenostomy to Treat Duodenal Perforation
In this study the investigators focused on duodenal perforations, requiring a tube duodenostomy and have analyzed the main features, that have influenced the surgical choices. Five patients were enrolled.
- Trial name
- NCT05359029
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Foggia
Cerebral Saturation, Cognitive Impairment
The Association Between Variation in Oxygen Saturation (ScO2) and Incidence of Postoperative Cognitive Dysfunction (POCD) in a Population of Elderly Patients Admitted for Emergency Surgery.
There is no study of the association between ScO2 and POCD in non-cardiac, thoracic or vascular surgery. The few studies found in cardiac, thoracic and vascular surgery show an incidence up to 50% with a variation of the ScO2…
- Conditions
- Cerebral Saturation, Cognitive Impairment, Emergencies
- Trial name
- NIRS-1 (NCT03107260)
- Testing
- To evaluate the relationship between oxygen saturation and the incidence of postoperative cognitive dysfunction in emergency surgery in elderly patients
- Where
- France
- Volunteers
- 181 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Emergencies, Surgery
Patient and Staff Experience of Ambulatory Emergency Care on the Surgical Admissions Unit (SAU)
Emergency ambulatory care ("day-case" care that does not involve staying in a hospital bed overnight) is now well-established for medical patients and is being used increasingly for surgical patients.
- Trial name
- NCT03514043
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Exeter
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Pregnancy Complications, Acute Appendicitis
Fetal Outcomes Among Pregnant Emergency General Surgery Patients
Approximately 1 in 500 pregnant women require non-obstetric surgery. Surgical care for the pregnant woman raises concern for complications adversely affecting pregnancy outcomes.
- Conditions
- Pregnancy Complications, Acute Appendicitis, Acute Cholecystitis, Biliary Pancreatitis
- Trial name
- NCT05085353
- Testing
- non-obstetric acute general surgical disease
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Methodist Health System
Frailty, Cardiac Surgery
SAGE-Heart : Senior Assessment fraGility and Post-opErative QALYs 1 Year After Emergency HEART Surgery for Patients Aged 75 and Older
The hypothesis is that the preoperative Clinical Frailty Score (CFS) is a predictive factor for a loss in quality-adjusted life years (QALYs) one year after emergency cardiac surgery under cardiopulmonary bypass (CPB) in patients…
- Conditions
- Frailty, Cardiac Surgery, QALYs
- Trial name
- SAGE-Heart (NCT07677319)
- Testing
- Phone Calls
- Where
- France
- Volunteers
- 265 people
- Sponsor
- University Hospital, Bordeaux
Pediatric Anesthesia, Emergence Delirium, Anesthesia
Impact of EEG-guided Sevofluorane on Opioid Consumption and Quality of Awakening
This prospective, randomized, single-blind, two-arm parallel-group clinical trial evaluates whether EEG-guided sevoflurane titration affects intraoperative opioid consumption and emergence quality in children undergoing painful…
- Conditions
- Pediatric Anesthesia, Emergence Delirium, Anesthesia, Postoperative Pain, Tonsillectomy
- Trial name
- NCT07714785
- Testing
- EEG-guided, Standard
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Emergency Surgery, Surgical Site Infections
Irrisept in Emergency General Surgery Patients
This is a single institution, randomized study conducted to determine if irrigation with Irrisept in emergency general surgery patients results in lower surgical site infections compared to normal saline irrigation.
- Trial name
- NCT07048899
- Testing
- Chlorhexidine, Normal Saline
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- The University of Texas Health Science Center at Tyler
Atrial Fibrillation
Medical Need of OAC Reversal
This is a retrospective, observational, claims cohort study to assess, for adult patients initiating an oral anticoagulant for NVAF
- Trial name
- NCT03254147
- Testing
- warfarin, dabigatran, Apixaban
- Where
- Japan
- Volunteers
- 53,969 people
- Sponsor
- Boehringer Ingelheim
Inguinal Hernia, Acute Appendicitis
The Onset Time of Rocuronium in Emergency and Elective Surgery
Rocuronium, a nondepolarizing neuromuscular blocking agent, is used in general anesthesia to provide conditions for endotracheal intubating.
- Trial name
- NCT02634255
- Testing
- Rocuronium elective surgery, Rocuronium emergency surgery, Propofol
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital