Clinical trials: Emergency Surgery Patients
Frailty, Surgery
An Investigation of Frailty Markers and Outcomes in Patients Requiring Emergency Laparotomy
Over 30,000 emergency abdominal operations (laparotomy, EmLAP) are performed in the UK annually and they are usually performed in adults over the age of 65.
- Conditions
- Frailty, Surgery, Sarcopenia
- Trial name
- NCT05416047
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Preoperative Ultrasound Assessment of the Upper Airway Can Predict Difficult Laryngscopy in Obese at Emergency Operations
Ultrasonography in Predicting Difficult Intubation in Obese Emergency Surgical Patients
Validity of ultrasonography in predicting difficult laryngoscopy and confirming endotracheal intubation in obese emergency surgical patients
- Trial name
- NCT05109221
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Minia University
Ultrasound, Children
The Rate of Full and Empty Stomach in Elective and Emergency Pediatric Patients
Background and Aim: Pulmonary aspiration of gastric content in the perioperative period is rare, but it is an important cause of morbidity and mortality that anesthetists never want to encounter.
- Conditions
- Ultrasound, Children, Surgery
- Trial name
- NCT04831593
- Testing
- Group El, Group Em
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ankara Children's Health and Diseases Hematology and Oncology Training and Research Hospital
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Acute Cholecystitis
TEXTBOOK OUTCOMES OF EMERGENCY CHOLECYSTECTOMIES IN ELDERLY PATIENTS
Textbook outcome is a measure used to assess the quality of surgical practice. The goal of this observational study is to compare textbook outcomes of elderly patients (≥65 years) in emergency cholecystectomies with younger…
- Trial name
- NCT06743217
- Where
- Turkey (Türkiye)
- Volunteers
- 212 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Respiratory Distress, Acute Lung Injury
Lung Injury Prediction Study
The purpose of the study is to externally validate the acute lung injury/acute respiratory distress syndrome (ALI/ARDS) prediction model (Lung Injury Prediction Score - LIPS) in a multicenter sample of patients at risk presented…
- Trial name
- USCTG-LIPS1 (NCT00889772)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Mayo Clinic
Frailty, Surgery--Complications
Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy
In the ProPEL study the effect of a protocol designed for elderly patients about to undergo emergency abdominal surgery will be investigated. The protocol addresses issues of both frailty and ceiling-of -care decisions.
- Conditions
- Frailty, Surgery--Complications, Outcome, Fatal, Frail Elderly Syndrome
- Trial name
- (ProPEL) (NCT04293653)
- Testing
- Protocol for patients above 75 undergoing emergency laparotomy or laparoscopy
- Where
- Norway
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
The Focus of Study is to Elucidate Which Are the Factors Requiring the Duodenostomy and Which Postoperative Course is for These Patients
Duodenostomy to Treat Duodenal Perforation
In this study the investigators focused on duodenal perforations, requiring a tube duodenostomy and have analyzed the main features, that have influenced the surgical choices. Five patients were enrolled.
- Trial name
- NCT05359029
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- University of Foggia
Abdomen, Acute, Myocardial Injury After Non-cardiac Surgery
The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery
Treatment of disorders such as gastrointestinal tract (GI) perforation, ischemia and obstruction often require acute high-risk abdominal surgery, which is associated with a high risk of complications such as myocardial injury…
- Conditions
- Abdomen, Acute, Myocardial Injury After Non-cardiac Surgery, Troponin I, Myocardial Injury
- Trial name
- NCT05992961
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 558 people
- Sponsor
- Nordsjaellands Hospital
Atrial Fibrillation, Venous Thromboembolism
Perioperative Anticoagulant Use for Surgery Evaluation Emergency Registry
Among patients who are receiving long-term anticoagulant therapy, whether with a direct oral anticoagulant (DOAC) or vitamin K antagonist (VKA), approximately 3-5% who require treatment interruption for a surgery will do so in an…
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Arterial Vascular Disease
- Trial name
- PAUSE-ER (NCT04195113)
- Where
- 3 sites in Canada
- Volunteers
- 242 people
- Sponsor
- McMaster University
Diabetes (Insulin-requiring, Type 1 or Type 2)
Investigation of the Effectiveness of Prophylactic NPWT (ciNPWT) in High-risk Diabetic Patients With Acute Laparotomy Wounds
The aim of this study is to evaluate the effectiveness of prophylactic Negative Pressure Wound Therapy (NPWT) in patients with diabetes mellitus undergoing laparotomy who are at high risk for Surgical Site Infections (SSI).
- Trial name
- NCT07392853
- Testing
- Prophylactic/Incisional Negative Pressure Wound Therapy
- Where
- Hungary
- Volunteers
- 110 people
- Sponsor
- Semmelweis University
Covid19, Surgery--Complications
Impact of the COVID-19 Pandemic on the Surgical Activity of Bellvitge University Hospital
COVID-19 has been a challenge for hospitals; there was an obvious need to reconvert many spaces in specific areas to attend this pathology, without forgetting the attention to other pathologies and surgery.
- Conditions
- Covid19, Surgery--Complications, Nosocomial Infection
- Trial name
- NCT04780594
- Testing
- The study evaluates all surgical patients operated, both elective scheduled and emergent cases
- Where
- Spain
- Volunteers
- 2,530 people
- Sponsor
- Hospital Universitari de Bellvitge
Postoperative Pulmonary Complications, Intra-abdominal Infection
The Effect of Continuous Intravenous Infusion of Lidocaine on PPCs and Prognosis in Emergency Surgical Patients With IAI
The main purpose of this study is to evaluate the impact of continuous 24-hour intravenous infusion of lidocaine on the incidence of PPCs in patients undergoing emergency laparotomy for intra-abdominal infection (IAI).The…
- Trial name
- PPCs (NCT06304779)
- Testing
- Lidocaine
- Where
- China
- Volunteers
- 428 people
- Sponsor
- Shanghai Zhongshan Hospital
VV-ECMO, Thoracic Surgery
Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery
Veno-vneous extracorporeal membrane oxygenation (VV-ECMO) is an established support strategy for acute respiratory failure, but its role in the perioperative management of emergency thoracic surgery remains poorly defined.
- Conditions
- VV-ECMO, Thoracic Surgery, Emergency Surgery, ARDS
- Trial name
- PECUR (NCT07016685)
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hemorrhage
CU Programme of Idarucizumab for Japanese Patients
The objective is to collect the safety data of idarucizumab for patients treated with dabigatran who require rapid reversal of the anticoagulant effects of dabigatran in cases of uncontrolled or life-threatening bleeding or when…
- Trial name
- NCT02831660
- Testing
- idarucizumab
- Where
- Japan
- Volunteers
- 1 people
- Sponsor
- Boehringer Ingelheim