Clinical trials: Emotional Processing
Healthy
Efficacy of Transcranial Electrical Stimulation (tES) on Emotion Processing
The aim of this study is to assess the efficacy of transcranial Electrical Stimulation (tES) on emotion processing of healthy participants.
- Trial name
- NCT04551118
- Testing
- Transcranial alternating current stimulation (tACS) -active, Transcranial direct current stimulation (tDCS)-active
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Tianjin Anding Hospital
Attention Deficit/Hyperactivity Disorder
Explore the Association Between the Emotion Recognition and the Attention Processing Under the Emotional Stimuli in ADHD
Lots of studies suggest that children with ADHD have deficits in facial emotion recognition, especially for the negative emotion.
- Trial name
- NCT02017483
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Attentional Processing, Adolescent Behavior
Games & Well-Being Study
This project is focused on the neural and behavioral correlates of two different videos games that will be used as training tools.
- Trial name
- GWB (NCT01886911)
- Testing
- Attention Training Intervention Game, Prosocial Training Intervention Game, Control for Attention Intervention
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Depressive Disorder, Treatment-Resistant
IMPase in Treatment-resistant Depression
This experimental medicine study will examine the effects of a brief period (seven days) of 'add on' ebselen (SPI-105) treatment in patients with resistant depression to see if ebselen produces changes in emotional responses…
- Trial name
- OxIMP (NCT05117710)
- Testing
- Ebselen
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Oxford
Healthy
Dose-dependent Effects of Oxytocin on the Amygdala and Reward System
The purpose of this study is to determine whether effects of intranasal oxytocin on amygdala and reward system responses vary as a function of treatment dose in women in comparison to men.
- Trial name
- NCT03846739
- Testing
- Oxytocin nasal spray
- Where
- Germany
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Depression
Sequence Towards Remission in Depression
In this study the investigators use clinical, biological and imaging markers to develop predictive markers for remission from depression.
- Trial name
- STRIDE (NCT01628783)
- Testing
- escitalopram 10 mg
- Where
- Finland
- Volunteers
- 90 people
- Sponsor
- Jesper Ekelund
Healthy
Effect of Gabapentin on GABA Concentration and Emotional Processing
This study will use magnetic resonance spectroscopy (MRS) and the drug gabapentin to examine the role of the brain chemical gamma-amino-butyric acid (GABA) in regulating emotions in healthy people.
- Trial name
- NCT00094510
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Mental Health (NIMH)
Emotional Processing, Mental Exercise
Effects of a Brief Mental Exercise on Emotional Processing
The aim of this study is to explore whether a brief mental exercise (developed and widely advocated in the field of positive psychology) can change the processing of emotion-related information in a similar way as previously…
- Trial name
- BME (NCT03698175)
- Testing
- Three good things exercise
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Emotions, Motivation
Pramipexole and Emotional Processing
The dopamine agonist pramipexole has recently been suggested as a potential novel antidepressant drug. While preliminary clinical data hint at its efficacy in treating depressive symptoms, our current understanding of its impact…
- Conditions
- Emotions, Motivation, Reward, Dopamine
- Trial name
- PEP (NCT03681509)
- Testing
- Pramipexole
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy
Selegiline and Reward Processing
There has been growing interest in the relationship between reward processing and clinical symptoms of depression such as anhedonia (loss of interest and response to pleasurable activities).
- Trial name
- NCT04130087
- Testing
- Selegiline Hydrochloride 10 MG
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Borderline Personality Disorder, Major Depression
Event Related Potentials in Borderline Personality Disorder and Major Depression
This study examines whether depression in people with borderline personality disorder is different than depression in people without borderline personality disorder. Unlike people who have depression alone (i.e.
- Trial name
- NCT01469663
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Sleep Deprivation
The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Processing in Young and Old
The main purpose of this study is to investigate the effects of partial sleep deprivation (PSD) on resting state brain connectivity, emotional contagion, empathy, and emotional regulation.
- Trial name
- NCT02000076
- Testing
- Partial sleep deprivation allowing 3 h sleep at night, Full sleep
- Where
- Sweden
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mats Lekander
Alcohol Use Disorder
Sex Differences, Cognitive Training & Emotion Processing
This pilot project addresses two understudied questions related to neurocognitive deficits observed in treatment-seeking alcoholics.
- Trial name
- NCT03137654
- Testing
- Affective Training, Neutral Training
- Where
- 5 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Florida
Depression, Inflammation
7-day Simvastatin and Emotional Processing
Work in our group has revealed that short-term (7-day) administration of antidepressants produces positive biases in the processing of emotional information in healthy volunteers.
- Trial name
- SSTEP-HV (NCT04652089)
- Testing
- Simvastatin 20mg
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Dysphoria
Neural Responses and Dysphoria: Modulation by a Pharmacological Probe
This study aims to improve understanding of how people with low mood and negative feelings (known as dysphoric) may be different from people with normal mood and feelings (nondysphoric) when responding to a variety of social and…
- Trial name
- NCT01101685
- Testing
- Escitalopram
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Adverse Childhood Experiences
The FACE Self-help App for Fostering Resilience
The FACE self-help app is an online intervention for young adults with Adverse Childhood Experiences (ACEs). It was developed based on well-established cognitive-behavioural therapy principles.
- Trial name
- NCT05824182
- Testing
- FACE self-help App
- Where
- Switzerland
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Jeannette Brodbeck
Depression, Alcohol, Drinking
Expressive Writing for Co-Occurring Depression and Alcohol Misuse
***Please note that this study does not offer comprehensive treatment program for alcohol abuse or depression. Please do not contact the study staff if you are seeking psychological treatment.
- Trial name
- NCT00818636
- Testing
- Expressive writing (in addition to group therapy as usual).
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Baylor College of Medicine
Anosognosia
THE DUAL-SYSTEM HYPOTHESIS OF ANOSOGNOSIA: The Interplay Between Emotional Processing and Self-Monitoring in Neurodegenerative Patients
The ASSESS project is a monocenter, regionally based, study evaluating the pathophysiological/functional processes underlying anosognosia in both AD and bvFTD.
- Trial name
- ASSESS (NCT06794580)
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Irritable Bowel Syndrome
Stress Management for Irritable Bowel Syndrome
The primary goal of this study is to test the efficacy of emotional awareness and expression training (EAET), a novel emotional processing intervention that the investigators have developed, for people with IBS.
- Trial name
- NCT01886027
- Testing
- Emotional Awareness and Expression Training, Relaxation Training
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Wayne State University
Mild-to-Moderate Stress
Prebiotic Effects on Anxiety, Cortisol, and Emotional Processing in Mild-to-Moderately Stressed Adults
The levels of stress that we experience as a population are continuing to rise due to financial, social and work pressures, particularly in mid-life where additional factors such as family and career often compound these issues.
- Trial name
- PEACE (NCT06991023)
- Testing
- Prebiotic (Bimuno®)
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University of Reading