Clinical trials: Endocrine Malignancy
Cancer Survivor, Diabetes Mellitus
Computed Tomography and Biomarker Analysis in Diagnosing Coronary Artery Disease in Asymptomatic Patients Who Have Undergone Stem Cell Transplant
This pilot clinical trial studies computed tomography (CT) scans and biomarker analysis in diagnosing coronary artery disease (CAD) in patients who have undergone a stem cell transplant but have no symptoms of CAD.
- Conditions
- Cancer Survivor, Diabetes Mellitus, Hypertension
- Trial name
- NCT02077218
- Testing
- computed tomography, cytology specimen collection procedure, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Polycystic Ovarian Syndrome
In-Vitro Maturation of Oocytes From Polycystic Ovarian Patients Undergoing IVF
Retrieval of immature oocytes from women with polycystic ovaries, their in-vitro maturation, fertilization and embryo transfer can prevent hormonal treatment that can lead to ovarian hyperstimulation.
- Trial name
- IVM (NCT00561808)
- Testing
- In-vitro maturation oocytes
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Non-small Cell Lung Cancer, Colorectal Cancer
ARGONAUT: Stool and Blood Sample Bank for Cancer Patients
ARGONAUT is a longitudinal, prospective, observational study that will enroll up to 5,000 advanced-stage cancer patients of diverse racial backgrounds to collect data used to develop precision microbiome medicines and for the…
- Conditions
- Non-small Cell Lung Cancer, Colorectal Cancer, Triple Negative Breast Cancer, Pancreas Cancer
- Trial name
- NCT04638751
- Testing
- Immunotherapy, Chemotherapy, CRC surgical resection
- Where
- 10 sites in United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Persephone Biosciences
Testicular Cancer, Testicular Self-Examination
Effects of Testicular Self-Examination Training Methods on Students' Behaviors and Health Beliefs
The goal of this cluster randomized controlled trial is to evaluate and compare the effects of different testicular self-examination (TSE) training methods on university students' health beliefs and self-examination behaviors…
- Conditions
- Testicular Cancer, Testicular Self-Examination, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT07841041
- Testing
- Educational Brochure and Audio Recording, Educational Brochure, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Healthy, Men
Bioavailability of Legume Proteins in Differents Products
The use of pea proteins could be interesting in specific foods. Indeed, these proteins could have great nutritional quality, with good amino acid profile.
- Trial name
- LEG'UP (NCT06624033)
- Testing
- amino acids kinetics
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Pancreatic Cancer, Thymic Cancer
Genetic Evaluation of Families With Endocrine Cancers
This study is being conducted to identify altered genetic factors that may exist and influence endocrine cancers in unrelated MEN1 families with different cancers.
- Conditions
- Pancreatic Cancer, Thymic Cancer, Parathyroid Disease, MEN1 Syndrome
- Trial name
- MEN1 (NCT01794676)
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Jersey Shore University Medical Center
Polycystic Ovary Syndrome (PCOS)
Fertility and Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age and affects approximately 10% of women worldwide.
- Trial name
- FERTIOPK (NCT07499518)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreas Cancer
Evaluation of CEMIP in Pancreatic Cancer
Pancreatic cancer (PC) is one of the most lethal diseases among all cancer types. The diagnosis of PC is usually based on radiology or invasive endoscopic techniques. Various types of tumor markers are used for diagnosing PC.
- Trial name
- NCT03679910
- Testing
- CEMIP , CA19-9 ,CEA, A) CBC . B) RBG. C)KFT. D) LFT.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Polycystic Ovary Syndrome
To Study the Effect of SC-FOS Prebiotics in Women With Polycystic Ovary Syndrome
The purpose of this study is to determine if there is a difference in the clinical characteristics of patients with polycystic ovary syndrome after the administration of SC-FOS in the enteral diet compared to patients with a…
- Trial name
- NCT05999097
- Testing
- Short Chain Fructooligosaccharides
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Chihuahua
Pancreatic Cancer
Detection of High Expression Levels of EMT-Transcription Factor mRNAs in Patients With Pancreatic Cancer and Their Diagnostic Potential
The present study is aimed at detecting and measuring mRNA levels of genes involved in epithelial to mesenchymal transition (EMT) in biological samples, i.e.
- Trial name
- NCT04323917
- Testing
- Liquid biopsy
- Where
- Italy
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Breast Cancer, Ovarian Cancer
Genetic Counseling in African American Women
The objectives of this study are to develop a Culturally Tailored Genetic (CTGC) protocol for African American women and evaluate its impact on decision making and satisfaction about BRCA1/2 testing, quality of life, and cancer…
- Trial name
- NCT00419510
- Testing
- Culturally Tailored Genetic Counseling
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Insulin Resistance, Polycystic Ovary Syndrome
Determinants of Insulin Sensitivity by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis
The study aims to investigate the relationship between fasting insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) across various demographic factors, including age, sex, race/ethnicity, BMI, and polycystic…
- Conditions
- Insulin Resistance, Polycystic Ovary Syndrome, Hyperinsulinism, Obesity
- Trial name
- DAISY (NCT05950282)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ali Chappell
Polycystic Ovary Syndrome
Serum Metabolomics Study of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a complex, heterogeneous disorder, which produces in 5-20% reproductive age women. In this study, a nontargeted metabolomics approach based on ultra high-performance liquid chromatography…
- Trial name
- NCT03618342
- Where
- China
- Volunteers
- 1,272 people, healthy volunteers welcome
- Sponsor
- Heilongjiang University of Chinese Medicine
Hyperthyroidism, Autoimmune, Cardiovascular Abnormalities
Clinical Application of Al18F-NOTA-FAPI-04 PET/CT or PET/MRI Imaging in Malignant Tumor,Cardiovascular or Immune Disease
This prospective, single-center study investigates the biodistribution, dosimetry, safety, diagnostic performance of Al18F-NOTA-FAPI PET imaging in patients with malignant tumor,cardiovascular or immune disease.
- Conditions
- Hyperthyroidism, Autoimmune, Cardiovascular Abnormalities, Malignant Tumor
- Trial name
- NCT07400224
- Testing
- Al18F-NOTA-FAPI PET/CT(or PET/MRI)
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Cancer
Research of the Application of Artificial Intelligence Model "PANDA"
The research objective of this project is to conduct a large-scale and prospective real-world validation of the Pancreatic Cancer Screening Model PANDA, which was developed based on deep learning and plain CT scans in previous…
- Trial name
- NCT06528223
- Testing
- biopsy or operation
- Where
- 2 sites in China
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Pancreatic Neoplasms
Adjuvant Gemcitabine Versus Gemcitabine With Chemoradiation in Pancreatic Adenocarcinoma With R1 Resection and/or Positive Lymph Nodes
Adjuvant Gemcitabine Versus Gemcitabine With Chemoradiation in Pancreatic Adenocarcinoma With R1 Resection and/or Positive Lymph Nodes after curative resection.
- Trial name
- NCT02754180
- Testing
- Gemcitabine, TS-1 with radiation
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Pancreatic Cancer, Gut Microbiota
The Mechanism of Enhancing the Anti-tumor Effects of CAR-T on PC by Gut Microbiota Regulation
Pancreatic cancer (PC) is one of the deadliest diseases of human digestive malignancies. Despite the recent advances in surgery and chemotherapy, the 5-year survival rate of PC continues to be less than 10%.
- Conditions
- Pancreatic Cancer, Gut Microbiota, CAR-T
- Trial name
- NCT04203459
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Ovarian Cancer
Short Non-coding RNA Biomarkers of Predisposition to Ovarian Cancer
The purpose of this study is to create new tests to identify biomarkers for ovarian cancer so that a screening test can be developed.
- Trial name
- sncRNA (NCT01187602)
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Unexplained Infertility, Polycystic Ovarian Syndrome
Nimodipine to Prevent LH Surge During Ovulation Induction: Blinded Placebo-controlled RCT
The main purpose of this study is to test the effectiveness of nimodipine in preventing a luteinizing hormone (LH) surge in women undergoing ovulation induction with clomiphene citrate.
- Conditions
- Unexplained Infertility, Polycystic Ovarian Syndrome, Anovulatory
- Trial name
- NIMO (NCT01672801)
- Testing
- Nimodipine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boston IVF
PCOS
PCOS and Brain Health
The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance.
- Trial name
- NCT07727512
- Testing
- MRI Visit, Laboratory Visit
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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