Clinical trials: Endocrine System Disorder
Cognitive Impairment, Dementia
Determinants of Cognitive Impairment Among Geriatrics
This study aims to explore the determinants of cognitive impairment among Indonesian geriatrics in an Old Age Home.
- Conditions
- Cognitive Impairment, Dementia, Hearing Impairment, Vision Impairment and Blindness
- Trial name
- NCT03669536
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tarumanagara University
Diabetes, Healthy
Investigating the Influence of Omeprazole on the Pharmacokinetics of Oral Semaglutide in Healthy Subjects
This trial is conducted in Europe. The aim of this trial is to investigate the influence of omeprazole on the pharmacokinetics (the exposure of the trial drug in the body) of oral semaglutide in healthy subjects.
- Trial name
- NCT02249871
- Testing
- semaglutide, Omeprazole
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus (T2DM), Cognitive Function
Prediabetes and Type 2 Diabetes in Aging
This case-control study will evaluate the effects of geriatric individuals on cognitive status, physical function and fatigue. Our study aims to compare the effects of geriatric individuals with prediabetes and type 2 diabetes…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cognitive Function, Dual Task, Fatigue
- Trial name
- NCT06953609
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Uşak University
Myopathy
Maintenance of Muscle Mass in Older People: the Negative Impact of Statin Therapy
A major contributor to frailty and immobility in the elderly is the age related loss of muscle mass (sarcopenia). Cardiovascular disease (CVD) is the leading cause of mortality in the elderly, with high blood cholesterol and…
- Trial name
- NCT01047163
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Ovulation Induction, Polycystic Ovary Syndrome
Effect of Adding Isoflavonoids to Clomiphene Citrate for Ovulation Induction in Women With Polycystic Ovary Syndrome
This prospective, randomized clinical trial double blinded study, has been carried on 160 infertile patients seeking pregnancy in Gynecology and Obstetrics Department, Zagazig University Hospitals during the period from January…
- Trial name
- NCT04610957
- Testing
- Rosafem (FEMININE FORMULA)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- FAlbasri
Hydration Status
The Impact of Self-assessment on Hydration
The studies objective is to assess the efficacy of hydration education and the use of a self-assessment worksheet vs. a no-intervention control on improving fluid intake and hydration status in underhydrated wildland firefighters…
- Trial name
- NCT06954909
- Testing
- Hydration education and self-assessment
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obesity, Diabetes Type 2
Pharmacogenetics of Response to GLP1R Agonists
Overweight/obese otherwise healthy volunteers will be recruited from the Old Order Amish population in Lancaster County, PA. Lancaster County, PA.
- Trial name
- PORT (NCT05071898)
- Testing
- Semaglutide Pen Injector [Ozempic]
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Heart Failure With Preserved Ejection Fraction, Type 2 Diabetes
Manganese-enhanced Magnetic Resonance Imaging (MEMRI) in Heart Failure With Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) is a condition in which the heart cannot fill with blood effectively. As a result, people with HFpEF suffer fatigue, breathlessness, and develop swollen limbs.
- Trial name
- MEMRI in HFpEF (NCT06652763)
- Testing
- Minnesota Living with Heart Failure Questionnaire, Echocardiogram, Six-minute walk test
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Adrenal Hyperplasia, Congenital, Congenital Hypothyroidism
Clinical Evaluation of NeoPlex4 Assay and NeoPlex System
The purpose of this study is to assess the agreement of clinical performance between the proposed NeoPlex 4 assay and NeoPlex System and the comparator devices in clinical use in newborn screening programs for detection of T4…
- Conditions
- Adrenal Hyperplasia, Congenital, Congenital Hypothyroidism, Cystic Fibrosis
- Trial name
- NCT01488721
- Where
- 3 sites in United States
- Volunteers
- 7,462 people, healthy volunteers welcome
- Sponsor
- Luminex Corporation
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Effectiveness and Safety Study of the Abbott Sensor Based Glucose Monitoring Systems
The purpose of the study is to evaluate the safety and effectiveness of the Abbott Sensor Based Glucose Monitoring System Personal (System-P) and Abbott Sensor Based Glucose Monitoring System Professional (System-Pro) when used…
- Trial name
- NCT02283411
- Testing
- Abbott Sensor Based Glucose Monitoring System
- Where
- 6 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Abbott Diabetes Care
Diabetic Retinopathy
Assessing of Artificial Intelligence-based Software Platform for Diabetic Retinopathy Screening
To examine the potential for the detection of diabetic retinopathy (DR) using the artificial intelligence (AI)-based software platform Retina-AI.
- Trial name
- ARTDR (NCT06879834)
- Testing
- taking fundus photos using non-mydriatic fundus camera
- Where
- Ukraine
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Filatov Institute of Eye Diseases and Tissue Therapy
Diabetic Foot Ulcer
Efficacy and Safety Study of Dermal-Living Skin Replacement to Treat Diabetic Foot Ulcers
The purpose of this study is to test the efficacy and side effects, if any, of Dermal - LSR combined with standard treatment. We hypothesize the treatment will provide beneficial results for diabetic patients suffering foot…
- Trial name
- NCT00368693
- Testing
- Dermal - Living Skin Replacement (Dermal-LSR)
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Type 1 Diabetes
Pancreas Volume in Preclinical Type 1 Diabetes
Type 1 diabetes (T1D) is characterized by a progressive destruction of insulin producing beta cells, resulting in a lifelong dependence on exogenous insulin.
- Trial name
- NCT02234947
- Testing
- MRI, US, and blood samples
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Florida
Type 2 Diabetes
The Pharmacokinetics Study of Single and Multiple Dose of SP2086 in Healthy Volunteers
SP2086 is a novel inhibitor of Dipeptide base peptidase 4, allows an insulin-independent approach to improve type 2 diabetes hyperglycemia.
- Trial name
- NCT02826044
- Testing
- SP2086
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
High-Risk Pregnancy
Longitudinal Measures of Leptin in Pregnant Women Who Developed Preeclampsia
Background: Obesity in pregnancy is increasing and is a risk factor for metabolic pathology such as preeclampsia. Leptin is an adipokine which has a direct relationship to obesity.
- Trial name
- NCT01649167
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Materno-Perinatal Hospital of the State of Mexico
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
The study is focused on the possible improving effect of N-acetylcysteine on nephropathy of type-2 diabetic patients. Study design: Prospective clinical based study.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetic Nephropathies
- Trial name
- (NAC) (NCT04531163)
- Testing
- N Acetylcysteine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Polycystic Ovarian Syndrome
In Vitro Maturation (IVM) for Polycystic Ovary Syndrome (PCOS)
This pilot study will be a prospective investigation to study the efficacy and safety of In-Vitro Maturation (IVM) for women with Polycystic Ovarian Syndrome (PCOS). There will be 10 subjects total in this Study.
- Trial name
- NCT01237106
- Testing
- IVM
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Reproductive Associates
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Effects of HBO on Glucose in Patients With DM
The purpose of this Research Study is: 1. To determine the reliability and performance of the Dexcom G6® continuous glucose monitoring (CGM) system in patients with diabetes undergoing hyperbaric oxygen (HBO2) exposure.
- Trial name
- NCT04261738
- Testing
- Hyperbaric Oxygen
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Legacy Health System
Assess the Effect of Green Tea on Diabetes, Assess the Effect of Fermented Papaya Pretration on Diabetes
Molecular and Clinical Effects of Green Tea and Fermented Papaya Preparation on Diabetes and Cardiovascular Diseases
Type 2 diabetes is common in ethnic and, minority groups in developing and developed countries such as Africans, African Americans, Asians, Native Americans, Hispano-Latinos and Alaskan indians.
- Conditions
- Assess the Effect of Green Tea on Diabetes, Assess the Effect of Fermented Papaya Pretration on Diabetes, Effects of Green Tea and FPP on C-reactive Proteins, Effects of Green Tea and FPP of Lipid Profiles in Diabetes
- Trial name
- NCT01248143
- Testing
- Green tea, FPP
- Where
- 3 sites in United States, Austria and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Diabetic Foot
Diabetic Foot Ulcer Prevention System
To evaluate a recently developed non-invasive infrared thermal camera called Diabetic Foot Ulcer Prevention System (DFUPS) in a clinical setting by studying healthy volunteers.
- Trial name
- DFUPS (NCT02317835)
- Testing
- DFUPS
- Where
- 3 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
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