Clinical trials: Endodontic Disease
Pulpotomy
Assessment of Pulpotomy Procedure Using NeoMTA Plus in Permanent Teeth With Carious Exposure
Many deep carious teeth are treated unnecessarily by root canal therapy, while with using current techniques and advances in compatible dental materials in addition to better understanding of biological response of the dental…
- Trial name
- PULPOTOMY (NCT03522051)
- Testing
- calcium silicate based material,
- Where
- Jordan
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Cryotherapy Effect
Intraoral Cryotherapy in Root Canal Retreatment
The aim of this study was to evaluate the effect of intraoral cryotherapy application on postoperative pain in single and multiple visit retreatment of teeth with symptomatic or asymptomatic apical periodontitis.
- Trial name
- NCT05091554
- Testing
- intraoral ice pack application
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Photochemotherapy Reaction, Dental Pulp Necrosis
Antimicrobial Photodynamic Therapy Associated With the Conventional Endodontic Treatment: A Clinical and Microbiological Study
Microorganisms play a critical role in the etiology and pathogenesis of apical periodontitis. Enterococcus faecalis and Candida sp. are frequently associated with persistent infections.
- Conditions
- Photochemotherapy Reaction, Dental Pulp Necrosis, Polymerase Chain Reaction, Infection
- Trial name
- NCT03212729
- Testing
- ANTIMICROBIAL PHOTODYNAMIC THERAPY, Conventional endodontic treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Endodontically Treated Teeth, Postoperative Pain
Different Endodontic Treatment Techniques in Postoperative Symptoms, Apical Repair, Longevity of Rehabilitations, and Oral Health-related Quality of Life
Objective: The objective of this study will be to evaluate the effectiveness of different endodontic treatment techniques in postoperative symptoms, apical repair, longevity of rehabilitations, and oral health-related quality of…
- Conditions
- Endodontically Treated Teeth, Postoperative Pain, Edema, Photochemotherapy
- Trial name
- NCT03704857
- Testing
- Foraminal Enlargement / Irrigating solutions / Filling materials, Photobiomodulation, Passive ultrasonic irrigation
- Where
- Brazil
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Necrotic Pulp
Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative Pain
To compare the effect of using Etidronate in sodium hypochlorite versus sodium hypochlorite irrigating solution on: Postoperative pain in patients with necrotic pulp.
- Trial name
- NCT04035330
- Testing
- etidronate in sodium hypochlorite, sodium hypochlorite
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontic Disease, Root Canal Infection
3D Analysis of Root Canal Conformation
Aim To evaluate in vivo the shaping ability of the canal with 3 different single-file systems: Reciproc Blue, WaveOne Gold and XP Endo-Shaper, using cone beam computed tomography and 3D reconstructions to measure canal volume…
- Trial name
- NCT03680534
- Testing
- Root canal preparation
- Where
- Colombia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institucion Universitaria Colegios de Colombia
Pulp Necrosis
Photo-Activated Disinfection Versus Triple-Antibiotic Paste for Management of Necrotic Young Permanent Anterior Teeth
This study aims to compare regenerative endodontics for necrotic young permanent anterior teeth using oral photo-activated disinfection versus triple antibiotic paste in terms of: 1.
- Trial name
- NCT03763110
- Testing
- Photo Activated Disinfection, antibiotic paste
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontic Disease
Evaluation of Antimicrobial Efficacy and Postoperative Pain After Using Silver Nanoparticles and Chitosan Nanoparticles Against Enterococcus Faecalis and Candida Albicans Biofilm
Silver nanoparticles possess unique physicochemical and biological properties in addition to their antibacterial capabilities. Similarly, zinc oxide nanoparticles have demonstrated antibacterial effects against a wide range of…
- Trial name
- NCT06172023
- Testing
- Silver Nanoparticles Irrigant, Chitosan Nanoparticles Irrigant
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Minia University
Pulpitis
Use of Tramadol Intraligamentary Injections
Introduction: To achieve painless treatment in patients with a failed primary IANB, supplementary anaesthesia has been advised. The majority of the studies evaluating intraligamentary injections have been performed on…
- Trial name
- NCT05538052
- Testing
- Tramadol hydrochloride, Lidocaine Hydrochloride
- Where
- India
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Jamia Millia Islamia
Root Canal Infection, Periapical Diseases
Microbial Load After Apical Enlargement in Asymptomatic Teeth With Periapical Lesion
The goal of this observational study is to define the role of apical shaping and irrigation activation on root canal cleanliness.
- Conditions
- Root Canal Infection, Periapical Diseases, Periapical; Infection, Endodontic Disease
- Trial name
- NCT06035185
- Testing
- apical shaping size
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Dental Caries
Three-Year Clinical Evaluation of Class II Posterior Composite Restorations
The aim of this study was to investigate the clinical effectiveness of direct resin composite restorations placed with different placement techniques (incremental or bulk) and with different flowable linings (conventional or…
- Trial name
- NCT02858947
- Testing
- Aelite Flo, x-tra base
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Tooth Injuries, Endodontically Treated Teeth
Regenerative Endodontic Treatment of Traumatised Teeth
Aim: The aim of this prospective study was to evaluate the treatment outcomes of regenerative endodontic technique (RET) for the management of traumatised non-vital immature teeth in children.
- Trial name
- NCT03045185
- Testing
- RET using Ciprofloxacin 100mg, and Metronidazole 100mg.
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Necrotic Pulp
Incidence of Post-Operative Pain After Single Visit Root Canal Treatment in Necrotic Teeth Using Two Different Rotary Systems (Protaper Nex t& Neolix File)
this prospective in vivo randomized clinical is to evaluate the post operative pain (incidence ,degree and duration) with multiple full rotation file (protaper next ®) and single full rotation file (Neolix®) in treating maxillary…
- Trial name
- NCT03059290
- Testing
- neolix file
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp
Efficacy of Guedes-Pinto Paste and CTZ Paste in the Non-instrumental Endodontic Treatment of Primary Teeth
The maintenance of the deciduous tooth until its physiological exfoliation occurs is one of the main objectives of pediatric dentistry.
- Trial name
- NCT04587089
- Testing
- Irrigation, Filling with Guedes-Pinto Paste, Filling with CTZ Paste
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Symptomatic Irreversible Pulpitis
Effect of Inferior Alveolar and Gow-Gates Nerve Block Techniques for Symptomatic Mandibular Molars
Introduction: to evaluate the efficacy of inferior alveolar nerve block (IANB), Gow-Gates nerve block (GGNB), and their combination in patients with irreversible pulpitis.
- Trial name
- NCT03117491
- Testing
- GGNB injections, IANB injections, GGNB + IANB injections
- Where
- Iran
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Irreversible Pulpitis, Primary Teeth
Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible Pulpitis
The present study aims to evaluate the clinical and radiographic success of pulpotomy using 3Mixtatin versus pulpectomy using Metapex in primary molars with irreversible pulpitis in children aged 4 to 9 years.
- Conditions
- Irreversible Pulpitis, Primary Teeth, Pulp Disease, Dental
- Trial name
- NCT06925490
- Testing
- Metapex, 3Mixtatin
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Dental Pulp Exposure
Stepwise and One Step Techniques In Deep Dentin Lesion
This double blind, randomized, controlled clinical trial aimed to observe the success of stepwise (SW) and one step (OneS) excavation techniques in the management of deep dentin caries.
- Trial name
- NCT04351048
- Testing
- Stepwise Excavation, One Step Excavation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TIJEN PAMIR
Endodontically Treated Teeth
Clini Asses of Retentn,Pt Satisfactn and Recurrent Caries of Endocrs Versus Post Crs Using Reinforced Lithium Silicate
Coronal retention of the restoration of RCT teeth is usually compromised, thus intraradicular posts combined or not with core material may be required.
- Trial name
- NCT03713918
- Testing
- Reinforced lithium silicate endocrowns, Post retained reinforced lith silicate crn
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Necrotic Pulp, Acute Apical Periodontitis of Pulpal Origin
Clinical Efficacy of Novel Jasminum-based Calcium Hydroxide Medicament
A triple-blind, parallel group, randomized trial with an allocation ratio of 1:1. Participants randomly allocated into two groups A and B.
- Trial name
- NCT06653608
- Testing
- Nano-reinforced calcium hydroxide medicament, Calcium hydroxide without nanoparicles
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Necrotic Pulp
Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants
To measure the Effect of Rosmarinus Officinalis versus 2.5%Sodium Hypochlorite as Root canal Irrigants on the Intensity of post-operative pain and Bacterial Reduction in asymptomatic necrotic Mandibular premolars.
- Trial name
- NCT05289843
- Testing
- Rosmarinus Officinallis
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University