Clinical trials: Endometriosis Associated Pelvic Pain
Endometriosis, Endometriosis-related Pain
Relugolix for Endometriosis Associated Pain
Endometriosis is a chronic, estrogen-dependent condition frequently associated with pelvic pain and reduced quality of life. Relugolix combination therapy (CT), an oral GnRH receptor antagonist-based treatment, has demonstrated…
- Conditions
- Endometriosis, Endometriosis-related Pain, Pelvic Pain Syndrome
- Trial name
- RELAX (NCT07440043)
- Testing
- Patients with a diagnosis of endometriosis receiving treatment with Relugolix CT, according to clinical practice,
- Volunteers
- 33 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pelvic Pain Associated With Endometriosis or Adenomyosis, Pelvic Pain Associated With Refractory Endometriosis
Efficacy and Tolerability of TENS in Endometriosis-related Pain
ELECTRE is a single-center, randomized, prospective, longitudinal, controlled, two-arm, single-blind study lasting 4 weeks (P1 investigation phase) after a 4-week run-in period.
- Conditions
- Pelvic Pain Associated With Endometriosis or Adenomyosis, Pelvic Pain Associated With Refractory Endometriosis, Endometriosis
- Trial name
- ELECTRE (NCT07393295)
- Testing
- Conventional TENS, Microstimulation TENS
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Monath Electronic
Endometriosis (Diagnosis)
Comparison of Elagolix and OCPs in Reducing Endometriosis Associated Pelvic Pain
This study is designed to provide direct evidence on the relative effectiveness and safety of Elagolix versus OCPs, helping physicians make more tailored treatment decisions.
- Trial name
- NCT07532876
- Testing
- Elagolix, Oral Contraceptive (OC)
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Pak Emirates Military Hospital
Endometriosis, Pelvic Pain
Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain
The goal of this clinical trial is to determine if Peer Empowered Endometriosis Pain Support (PEEPS), an 8-week interdisciplinary, integrative group care program, decreases pain interference in participants with…
- Trial name
- PEEPS RCT (NCT06549985)
- Testing
- PEEPS, Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Endometriosis
A Study to Assess the Efficacy and Safety of OBE2109 in Subjects With Endometriosis
The primary objective of this study is to assess the efficacy and safety of a range of oral doses of OBE2109 versus placebo, in reducing endometriosis associated pain.
- Trial name
- EDELWEISS (NCT02778399)
- Testing
- OBE2109
- Where
- 86 sites in United States, Poland and 2 more
- Volunteers
- 328 people
- Sponsor
- ObsEva SA
Endometriosis
Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain
The primary objective of this extension study is to assess the maintenance of efficacy of linzagolix administered orally once daily for up to an additional 6 months (for up to 12 months of treatment in total) in women who have…
- Trial name
- EDELWEISS 5 (NCT04372121)
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 25 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Endometriosis
A Phase 3 Study to Confirm the Efficacy and Safety of Linzagolix to Treat Endometriosis-associated Pain
The primary objective of this study is to demonstrate the efficacy and safety of linzagolix administered orally once daily for 3 months at a dose of 75 mg alone or of 200 mg in combination with add-back hormone replacement…
- Trial name
- NCT03986944
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 112 sites in United States, Canada and 1 more
- Volunteers
- 85 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Endometriosis, Pelvic Pain
Medical Treatment of Endometriosis-Associated Pelvic Pain
The Specific Aim of this project is to compare the efficacy and cost-effectiveness of continuous oral contraceptives versus leuprolide/norethindrone in the treatment of endometriosis-associated chronic pelvic pain.
- Trial name
- NCT00229996
- Testing
- Oral Contraceptive, Depot-Leuprolide/Norethindrone
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis
A Clinical Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in adult premenopausal female participants.
- Trial name
- ELARIS EM-I (NCT01620528)
- Testing
- elagolix
- Volunteers
- 872 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Endometriosis Associated Pelvic Pain
A Study to Learn More About How Safe Dienogest is and How Well it Works Under Real World Conditions in Indian Women With Endometriosis
Endometriosis is a condition that affects women, usually during their reproductive years. In women with endometriosis, the tissue that normally covers the inside of the womb grows outside the womb.
- Trial name
- VISAGE (NCT04808843)
- Testing
- Dienogest (BAY86-5258, Visanne)
- Where
- India
- Volunteers
- 160 people
- Sponsor
- Bayer
Endometriosis
Effect of Physical Activity and Pain Education on Endometriosis-associated Pain
Endometriosis is a benign gynecological condition where the uterine endometrium is located outside the uterus. The condition affects up to 10% of women of fertile age and up to 70% of women with endometriosis have symptoms with…
- Trial name
- NCT05091268
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 83 people
- Sponsor
- University Hospital, Akershus
Dysmenorrhea, Dyspareunia
Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women
The purpose of the study is to evaluate the efficacy and safety of two doses of ERB-041 (75 mg and 150 mg) relative to placebo on the relief of endometriosis-related symptoms (dysmenorrhea, pelvic pain, and deep dyspareunia) in…
- Conditions
- Dysmenorrhea, Dyspareunia, Endometriosis, Pelvic Pain
- Trial name
- NCT00318500
- Testing
- ERB-041
- Where
- 70 sites in United States, Australia and 5 more
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Endometriosis
Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Adults With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the continued safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in pre-menopausal women.
- Trial name
- NCT01760954
- Testing
- Elagolix
- Volunteers
- 506 people
- Sponsor
- AbbVie
Endometriosis and Dysmenorrhea
Drug Use Investigation (DUI) of YazFlex for Endometriosis-associated Pelvic Pain and/or Dysmenorrhea
This study is a Japanese post-marketing surveillance (PMS) which is required by the regulatory authorities. General objective of PMS is to confirm the clinical usefulness, especially the safety profile of a drug under the routine…
- Trial name
- NCT03126747
- Testing
- BAY86-5300_YAZ-Flex
- Where
- Japan
- Volunteers
- 715 people
- Sponsor
- Bayer
Endometriosis Related Pain
SPIRIT 2: Efficacy and Safety Study of Relugolix in Women With Endometriosis-Associated Pain
The purpose of this study is to determine the benefit and safety of relugolix 40 milligrams (mg) once daily, co-administered with low-dose estradiol (E2) and norethindrone acetate (NETA) compared with placebo for 24 weeks, on…
- Trial name
- NCT03204331
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 91 sites in United States, Australia and 9 more
- Volunteers
- 623 people
- Sponsor
- Myovant Sciences GmbH
Endometriosis, Endometriosis (Diagnosis)
Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With Endometriosis
Endometriosis is a chronic inflammatory disease affecting approximately 10% of women in their reproductive years. It is characterized by the presence of endometrial-like tissue outside the uterine cavity.
- Conditions
- Endometriosis, Endometriosis (Diagnosis), Endometriosis and Dysmenorrhea, Endometriosis Associated Pelvic Pain
- Trial name
- NCT07821320
- Testing
- Desloratadine
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Dysmenorrhea
Efficacy and Safety, Long-Term Study of NPC-01 to Treat Dysmenorrhea Associated With Endometriosis
The purpose of this long-term study is to determine whether NPC-01 is effective in the treatment of dysmenorrhea associated with endometriosis.
- Trial name
- NCT00902746
- Testing
- NPC-01
- Volunteers
- 149 people
- Sponsor
- Nobelpharma
Dysmenorrhea
Efficacy and Safety,Long-term Study of Low-dose Oral Contraceptive Pill to Treat Dysmenorrhea.
The purpose of this long-term study is to determine whether combination oral contraceptive pill of Norethindrone \& Ethinyl estradiol is effective in the treatmentof dysmenorrhea associated with endometriosis.
- Trial name
- NCT00212277
- Testing
- Norethindrone,Ethinyl Estradiol
- Sponsor
- Nobelpharma
Endometriosis
Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain.
The primary objective of this study is to demonstrate the efficacy and safety of linzagolix administered orally once daily for 3 months at a dose of 75 mg alone or of 200 mg in combination with add-back hormone replacement…
- Trial name
- NCT03992846
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 71 sites in United States, Austria and 8 more
- Volunteers
- 486 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Chronic Pain, Endometriosis
THE EFFECT OF tDCS IN THE TREATMENT OF CHRONIC PELVIC PAIN ASSOCIATED WITH ENDOMETRIOSIS
The purpose of this study is to determine if transcranial direct current stimulation (tDCS) is effective in the treatment of chronic pelvic pain associated with endometriosis
- Trial name
- tDCS (NCT02161302)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre