Clinical trials: Endoscopic Assessment
Gastric Neoplasm, Gastric Lesion
Single-center, Randomized, Superiority Pivotal Clinical Study to Evaluate the Efficacy of Artificial Intelligence-based Upper Gastrointestinal Endoscopy Image
We will conduct a single-center retrospective study at a university hospital. A total of 3,385 gastroscopic white-light images from patients with pathologically confirmed findings will be analyzed.
- Conditions
- Gastric Neoplasm, Gastric Lesion, Artificial Intelligence
- Trial name
- NCT06969794
- Where
- South Korea
- Volunteers
- 3,385 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Intubation;Difficult, Gastrointestinal Bleeding
Evaluation of Prophylactic Endotracheal Intubation
Upper gastrointestinal (GI) bleeding is defined as patients who either presented with hematemesis or presented with melena along with evidence of hemodynamic compromise.
- Trial name
- NCT03716466
- Testing
- Endotracheal intubation, No airway intervention
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Texas Southwestern Medical Center
Ureteral Stricture
EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures
The main objective of this clinical investigation is to assess the safety and feasibility of the Optilume DCB for treatment of ureteric strictures.
- Trial name
- ENDURE1 (NCT07020520)
- Testing
- Optilume
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Urotronic Inc.
Colon Cancer, Surgery
Evaluation the Safety of Indocyanine Green Guided Treatment of Henle Trunk
Laparoscopic right hemicolectomy D3 dissection or complete mesocolic excision (CME) has become the standard treatment for right hemi-colon cancer, and the treatment of Henle trunk is one of the difficulties of the operation.
- Trial name
- SIGHELC (NCT05125393)
- Testing
- Laparoscopic linear stapler
- Volunteers
- 128 people
- Sponsor
- Shanghai East Hospital
Silent Aspiration, Post-Extubation Dysphagia
Silent Aspiration Following Extubation in the ICU
Post-extubation dysphagia is common in critically ill patients and may lead to silent aspiration, which often remains undetected because patients do not exhibit overt clinical signs such as coughing or choking.
- Conditions
- Silent Aspiration, Post-Extubation Dysphagia, Deglutition Disorders, Critical Illness
- Trial name
- SAFE-ICU (NCT07635888)
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing (FEES)
- Where
- United Arab Emirates
- Volunteers
- 274 people
- Sponsor
- Cleveland Clinic Abu Dhabi
Colorectal Cancer
Polyprev: Study to Compare Fecal Immunochemical Test With Endoscopic Surveillance After Advanced Adenoma Resection in Fecal Immunochemical Test Colorectal Cancer Screening Programs.
Colorectal cancer (CRC) screening programs have been implemented to reduce the burden of the disease. When an advanced colonic lesions is detected, it is recommended to perform endoscopic surveillance with different intervals…
- Trial name
- NCT04967183
- Testing
- Annual FIT, Endoscopic surveillance.
- Where
- Spain
- Volunteers
- 3,788 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Breast Cancer
Duct Endoscopy in Assessing Cellular Atypia in the Breast Duct Fluid of Women With a Genetic Risk for Breast Cancer
RATIONALE: Diagnostic procedures, such as breast duct endoscopy, may improve the ability to detect breast cancer earlier and plan more effective treatment.
- Trial name
- NCT00082979
- Testing
- cytogenetic analysis, proteomic profiling, cytology specimen collection procedure
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Critically Ill
Evaluation of Two Methods of Jejunal Placement of Enteral Feeding Tubes in Critically Ill Patients
In patients with high gastric residual volumes jejunal feeding is recommended. Jejunal feeding tubes can be placed in different ways.
- Trial name
- NCT00807287
- Testing
- Jejunal tube placement using the unguided frictional method, Jejunal tube placement using the endoscopic method
- Where
- Austria
- Volunteers
- 42 people
- Sponsor
- Medical University of Vienna
Barrett Esophagus, Esophageal Neoplasms
Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus
Multispectral imaging represents an exciting new field of investigation in endoscopic research. Multispectral imaging uses a specialised camera to detect multiple colours, allowing us to build a rough spectrum from each point in…
- Conditions
- Barrett Esophagus, Esophageal Neoplasms, Reflux Esophagitis
- Trial name
- MuSE (NCT03388047)
- Testing
- Endoscopy with Polyscope (Polydiagnost TM) coupled with Multi-Spectral Imaging light-source
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Cambridge
Pancreatic Cancer, Pain
Evaluation of Injection Techniques in Celiac Plexus Neurolysis
1. To evaluate the efficacy of EUS-CPN in subjects who experience a sympathetic response during injection when compared with subjects who do not experience sympathetic response during injection.
- Trial name
- NCT02068677
- Testing
- Sympathetic response, no sympathetic response
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- AdventHealth
Inflammatory Bowel Diseases
A Diagnostic Accuracy Study Testing Fecal Biomarkers In Comparison To Endoscopic Examination
In this study it will be explored whether the levels of fecal biomarkers are associated with histologic inflammation of the intestinal mucosa and concomitant alteration of the mucosal permeability.
- Trial name
- NCT04849936
- Testing
- Testing Fecal Biomarkers In Comparison To Endoscopic Examination With Confocal Laser Endomicroscopy
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Universität Duisburg-Essen
Pancreatic Neoplasms, CHRONIC PANCREATITIS
Needle-based Confocal Endomicroscopy Examination of Pancreatic Masse
Introduction: Pancreatic cancer is one of the most aggressive malignancies with only 5% of patients being alive at five years. EUS (endoscopic ultra sound) is an established, sensitive diagnostic tool in pancreatic cancer and for…
- Trial name
- NCT01734967
- Testing
- needle based CLE, EUS-FNA
- Where
- 2 sites in Denmark, Romania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Capsule Endoscopy
Mini-sized MCE for Better Examination of UGI and Small Bowel
A mini-sized MCE highlighted with a diameter of 9.5mm, a length of 24.5mm, and a weight of 3.0g has been developed. This new type of MCE is approximately 0.6 times the conventional MCE (27mm*11.8mm) in volume and weight, and it…
- Trial name
- NCT05073536
- Testing
- mini-sized MCE, normal-sized MCE
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Barrett's Esophagus
Comparative Effectiveness of Endoscopic Assessment of Gastroesophageal Reflux and Barretts Esophagus
The hypothesis of this study was that the comparative effectiveness of unsedated transnasal endoscopy (uTNE) will be greater than sedated endoscopy (sEGD) in population screening for BE.
- Trial name
- challenge (NCT01288612)
- Testing
- Sedated Endoscopy, Transnasal Endoscopy
- Where
- United States
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Procedural Sedation, Gastrointestinal Endoscopy
SED Pack: Safety and Performance of a Medical Device Software for Predictive Monitoring During Sedation
The SED-PACK study is a prospective, observational, single-center clinical investigation evaluating the clinical performance and safety of SED Pack, a Medical Device Software (MDSW) developed by Predictheon Medical S.L., in a…
- Trial name
- NCT07749781
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Predictheon Medical, S.L.
Urolithiasis
Kidney Stone Calculator
Urolithiasis is a frequent pathology, for which flexible ureteroscopy with endocorporeal laser lithotripsy has become the most frequently used surgical treatment.
- Trial name
- KSC (NCT05707988)
- Where
- France
- Volunteers
- 223 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Platelet-rich Plasma, Endoscopic Mucosal Resection
Evaluation of the Efficacy of Platelet-rich Plasma (PRP) on Advanced Endoscopic Resection Techniques
To avoid complications secondary to advanced endoscopic resection techniques (Endoscopic Mucosal Resection -EMR- or Endoscopic Submucosal Disection -ESD-) the endoscopists have to avoid deep thermal damage and increase mucosal…
- Conditions
- Platelet-rich Plasma, Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection
- Trial name
- NCT02931149
- Testing
- Platelet-rich plasma
- Where
- Spain
- Volunteers
- 11 people
- Sponsor
- Germans Trias i Pujol Hospital
Pseudocyst, Walled Off Cavity
Evaluation of the Outcomes and Performances of the Application of Augmented Reality in Operative Digestive Endoscopy
Virtual reality obtained by the fusion of images can be applied to several fields of medicine leading to the so called "augmented reality".
- Trial name
- NCT04698668
- Testing
- fusion imaging
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Sedoanalgesia
Effectivity of Bispectral Index Monitoring in Cases of Endoscopic Retrograde Cholangiopancreatography
The bispectral index (BIS) monitoring is an EEG-based method that uses electroencephalogram analysis and a complex algorithm to generate a numerical scoring 0-100 (0 flat line EEG, 100, wide awake) BIS monitoring allows…
- Trial name
- NCT03114774
- Testing
- The bispectral index (BIS) monitoring, Ramsay Sedation Scale (RSS) Score monitoring
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
Buried Bumper Syndrome
Endoscopic Treatment of the Buried Bumper Syndrome: Comparison of the Flamingo Device Versus Standard Therapy
Percutaneous endoscopic gastrostomy (PEG) is a method for nutrition delivery for patients with insufficient oral intake. A rare but severe complication of PEG is the Buried Bumper Syndrome (BBS).
- Trial name
- ESCAPE (NCT03186066)
- Testing
- Flamingo Device, Standard Therapy
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Kliniken Ludwigsburg-Bietigheim gGmbH