Clinical trials: Endoscopic Suturing
Obesity
Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass
It is estimated that up to 20% of patients who have Roux-en-Y Gastric Bypass (RYGB) surgery will not meet their weight loss goal, or may even regain some of the weight they initially lost.
- Trial name
- NCT00394212
- Testing
- Transoral Suturing
- Where
- 10 sites in United States
- Volunteers
- 77 people
- Sponsor
- C. R. Bard
Obesity, Obesity, Morbid
Endoscopic Sleeve Gastroplasty Technique Comparison for Weight Loss
The Investigators propose suture plication placement at the distal gastric body drives a significant portion of weight loss in endoscopic sleeve and sutures only need to be placed in the distal gastric body.
- Conditions
- Obesity, Obesity, Morbid, Metabolic Disease, Weight, Body
- Trial name
- NCT06299644
- Testing
- Endoscopic Sleeve Gastroplasty - Belt and Suspenders, Endoscopic Sleeve Gastroplasty - Belt
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
GERD
Endomina Suturing Device as a Treatment of GERD.
Gastroesophageal Reflux Disease (GERD) is a common problem affecting 10-20% of the population in the Western World. Surgical therapy is able to restore the EGJ barrier function against reflux of the gastric content, decreases…
- Trial name
- NCT03999502
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Erasme University Hospital
Colonic Polyp, Gastrointestinal Neoplasms
Clinical Study on Continuous Suture of Endoscopic Mucosal Defects
The use of clips to completely clip mucosal defects after ESD/EMR can reduce postoperative adverse events, but the rate of incomplete mucosal defects closure is high.
- Trial name
- NCT05190042
- Testing
- Cotinuous suture, Clips
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Myoma
Multi-center Prospective Study on E-NOTES for Myomectomy With Traction of Multidirectional Sutures
Primary objectives : To investigate technical feasibility and postoperative morbidity after E-NOTES for Myomectomy with Traction of Multidirectional Sutures Secondary objectives : To investigate postoperative pain after E-NOTES…
- Trial name
- E-NOTES (NCT01829022)
- Testing
- E-NOTES
- Where
- 2 sites in South Korea
- Volunteers
- 35 people
- Sponsor
- National Cancer Center, Korea
Obesity
The USGI Medical ESSENTIAL Study for Weight Loss
This is a multicenter, randomized, evaluator and subject blinded, parallel-group, controlled study intended to evaluate the safety and efficacy of treating obese patients with the placement of g-Cath EZ suture anchors followed by…
- Trial name
- NCT01958385
- Testing
- placement of g-Cath EZ suture anchors, Diet and Exercise
- Where
- 11 sites in United States
- Volunteers
- 377 people
- Sponsor
- USGI Medical
Submucosal Tumor of Intestine
Endomina as an Aid for Endoscopic Full Thickness Resection
The concept of natural orifice transluminal endoscopic surgery (NOTES) (1) has evolved to endoscopic full thickness resection (EFTR).
- Trial name
- EFTR (NCT03608540)
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Erasme University Hospital
Bariatric Surgery, Morbid Obesity
Use of an Endoluminal-suturing Device for Endoscopic Gastric Reduction as an Aid for Class I Obesity, or Class II Obesity Without Comorbidity
The primary objective is to measure the impact of this treatment for patients with obesity of class I, or class II without co-morbidity, assessed by excess weight loss (EWL)>25%.
- Trial name
- SLEEVE (NCT03900481)
- Testing
- Vertical gastric plication
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Endoscopic Suturing, GI Tract Disorders
Gastrointestinal Tract Disorders: A Prospective Multicenter Registry
The purpose of this prospective registry is to assess long-term data on efficacy, safety and clinical outcome of endoscopic placement of suture(s) and approximation of soft tissue within the gastrointestinal tract for various GI…
- Conditions
- Endoscopic Suturing, GI Tract Disorders, Gastrointestinal Disorders
- Trial name
- NCT05127408
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Methodist Health System
Prostate Cancer
Staple vs. Suture in Robotic Prostatectomy
The purpose of the study is to compare the results of three standard of care surgical methods [stapling versus selective suture ligation (cut, then sew) versus single suture ligation (sew, then cut) of the dorsal venous complex…
- Trial name
- NCT03480074
- Testing
- Staple Ligation, Selective Suture Ligation, Single Suture Ligation
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Swedish Medical Center
Esophageal Strictures, Esophageal Leak
Esophageal Stent Migration With Endoscopic Suture Fixation Compared to Standard Deployment
Esophageal stents are commonly used for benign esophageal pathology, especially strictures or esophageal mucosal defects such as leaks, fistulae, or perforations.
- Conditions
- Esophageal Strictures, Esophageal Leak, Esophageal Perforation, Esophageal Fistula
- Trial name
- NCT02751333
- Testing
- FCSEMS with Endostitch (ES), FCSEMS with No Suturing (NS), Fully Covered Self-Expanding Metal Stents (FCSEMS)
- Where
- United States
- Sponsor
- Johns Hopkins University
Achalasia, Gastric Outlet Obstruction
Endoscopic Surgery for Gastrointestinal Disorders: A Multicenter Registry Study
Currently, there is limited multi-center data on endoscopic surgery outcomes in western populations. Evaluation of these measurement would help the investigators compare them to conventional treatment modalities within current…
- Conditions
- Achalasia, Gastric Outlet Obstruction, Gastroparesis, GERD
- Trial name
- NCT05041608
- Testing
- Endoscopic Surgery
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Advanced Endoscopy Research, Robert Wood Johnson Medical School Rutgers University
Obesity
A Prospective Study to Evaluate the Suture Pattern With the Endomina Suturing Device for Endoscopic Sutured Gastroplasty (ESG).
Advances in endoluminal devices are now allowing clinicians the ability to begin exploring bariatric procedures performed via flexible endoscopy.
- Trial name
- Pattern (NCT03843801)
- Testing
- Endomina
- Where
- 2 sites in Belgium
- Volunteers
- 46 people
- Sponsor
- Erasme University Hospital
the Management of Weight Regain After Gastric Bypass by Endoscopic Suturing
Assessment of the Overstich Technique for the Management of Weight Regain After Gastric Bypass.
Prospective multicenters randomized study to compare the efficiency and the socioeconomic impact of the endoscopic management (Overstitch technique) of weight regain after gastric bypass surgery to non invasive treatment
- Trial name
- APOLLO (NCT02048033)
- Testing
- Regular endoscopy + endogastric suturing, Regular endoscopy
- Where
- 7 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Weight Loss
A Prospective Study to Evaluate the Efficacy of an Endoluminal-suturing Device (Endomina TM) as an Aid for Endoscopic Gastric Reduction.
Surgery is the only effective treatment for morbid obesity and can be divided into restrictive surgeries (Lap Band and Sleeve gastrectomy), malabsorptive surgeries (Biliary pancreatic deviation and duodenal switch) or a…
- Trial name
- Endomina (NCT02582229)
- Testing
- Endomina
- Where
- 3 sites in Belgium, Czechia and 1 more
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Endoscopic Mucosal Resection, Endoscopic Submucosal Dissection (ESD)
Endoscopic Full Thickness Suturing of Mucosal, Submucosal and Perforation Defects Using Su2ura® GI System
The objective of this clinical study is to assess the safety of the Su2ura® GI system when used for endoscopic suturing and soft-tissue approximation in patients referred for endoscopic mucosal resection (EMR) or endoscopic…
- Trial name
- NCT07315893
- Testing
- Su2ura® GI system, Physical Examination, Vital Signs
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Anchora Medical
Early Gastric Cancer
Non-exposure Simple Suturing EFTR (NESS-EFTR) With Laparoscopic Sentinel Lymph Node Navigation for EGC (Senorita3-phase 2)
Laparoscopic sentinel lymph node dissection and stomach preserving surgery in early gastric cancer is less invasive method which can increase quality of life.
- Trial name
- NCT03837301
- Testing
- NESS-EFTR with sentinel lymph node navigation
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- National Cancer Center, Korea
Wound Healing
Clinical Effect of Endoscopic Surgery for Delayed Wound Healing After Achilles Tendon Suture
This study proposes endoscopic surgery for delayed wound healing after Achilles tendon suture which is a brand new treatment，and retrospectively analyzed the clinical data of 4 cases treated with this treatment.
- Trial name
- NCT04455490
- Testing
- Self-control
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Peking University Third Hospital
Obesity
Endoscopic Suturing System for Tissue Apposition
The objective of this feasibility trial is to evaluate the Ethicon Endo-Surgery Endoscopic Suturing System (ESS) for tissue apposition and reduction of the size of a dilated GJ anastomosis in subjects who are regaining weight…
- Trial name
- NCT00495222
- Testing
- Tissue plication, Endoscopic Suturing System
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ethicon Endo-Surgery
Suture Techniques, Medical Glue
Innovative Suture Technique for Endoscopic Hernia Incision
The minimally invasive surgical technique represented by endoscopy is one of the most important inventions in the medical field of the 20th century.
- Trial name
- NCT05781932
- Testing
- Dermal barb suture combined with medical glue
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Yizhuo Lu, MD