Clinical trials: Endovascular Treatments
Acute Ischemic Stroke, Endovascular Treatment
Early vs Delayed Extubation After Endovascular Treatment for Acute Ischemic Stroke
Although older studies, most of them retrospective in design, advocated sedation over general anesthesia during endovascular treatment for acute ischemic stroke, a recent meta-analysis and randomized studies have shown that…
- Trial name
- EDESTROKE (NCT05847309)
- Testing
- Delayed extubation, Early extubation
- Where
- Spain
- Volunteers
- 174 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Aortic Aneurysm
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Thoracal Abdominal Aneurysms
The aim of this study is to prospectively compare the perioperative mortality severe morbidity and the costs of endovascular versus conventional surgical repair of type 1, 2 and 3 thoracal abdominal aortic aneurysms.
- Trial name
- Windows2 (NCT01354821)
- Testing
- Endovascular aortic repair, Open surgical repair
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hepatic Cancer, Metastatic Cancer
Prevention and Treatment of Complications of Endovascular Methods in Patients With Malignant Liver Tumors
In the structure of malignant liver lesions, two main groups are distinguished - primary liver cancer and metastatic liver damage. The five-year survival rate of patients with malignant liver tumors does not exceed 6%.
- Conditions
- Hepatic Cancer, Metastatic Cancer, Chemotherapy Effect
- Trial name
- PATOC (NCT04764409)
- Testing
- Chemoembolization, Chemoinfusion
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- Central Clinical Hospital RZD-Medicine, Russian Federation
Abdominal Aortic Aneurysm Without Rupture
The British Society of Endovascular Therapy ConformabLe EndoVascular Aneurysm Repair Registry
The purpose of the BSET-CLEVAR Registry is to collect device-specific performance outcomes of the GORE® EXCLUDER® Conformable AAA Endoprosthesis with ACTIVE CONTROL System (EXCC device) in routine clinical treatment of patients…
- Trial name
- BSET-CLEVAR (NCT03966521)
- Where
- 13 sites in United Kingdom
- Volunteers
- 105 people
- Sponsor
- Imperial College London
Stroke, Acute
Early Neurological Clinical Recovery, 3 Months After Endovascular Treatment of an Acute Ischemic Stroke
This trial aims at collecting standardized data concerning the early neurological clinical recovery of patients, 3 months after endovascular treatment of an acute ischemic stroke.
- Trial name
- AVC-endovasc (NCT02879123)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Acute Ischemic Stroke
Sedation vs. Intubation for Endovascular Stroke TreAtment
Sedation vs Intubation for Endovascular Stroke TreAtment Trial (SIESTA) is a prospective, randomised controlled, monocentric, two-armed, comparative trial.
- Trial name
- SIESTA (NCT02126085)
- Testing
- Endovascular recanalisation
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University Hospital Heidelberg
Limb Ischemia
Combined Management in ALI ( Image Guided Thrombectomy With Open Transfemoral Access )
Acute limb ischemia (ALI) is a sudden decrease in limb perfusion due to either an embolic or a thrombotic vascular occlusion, defined as the presence of symptoms within two weeks of onset.
- Trial name
- NCT04622878
- Testing
- thrombectomy and PTA
- Volunteers
- 100 people
- Sponsor
- Assiut University
Coronary Artery Disease, Aortic Atherosclerotic Disease
Evaluation of the Strategy of "One-stop" Endovascular Treatment for Concomitant Coronary Artery Disease and Aortic Atherosclerotic Disease
The study is a prospective, randomized, controlled, exploratory trail to evaluate the strategy of "one-stop" endovascular treatment for concomitant coronary artery disease and aortic atherosclerotic disease.
- Trial name
- NCT03563768
- Testing
- One-stop strategy group
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Stroke, Acute, Cerebral Infarction
Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3
This is a study to evaluate the hypothesis that FDA cleared thrombectomy devices plus medical management leads to superior clinical outcomes in acute ischemic stroke patients at 90 days when compared to medical management alone…
- Trial name
- DEFUSE 3 (NCT02586415)
- Testing
- Endovascular Thrombectomy, Trevo Retriever, Solitaire™ FR Revascularization Device
- Where
- 40 sites in United States
- Volunteers
- 182 people
- Sponsor
- Gregory W Albers
Critical Limb Ischemia
Registry of First-line Treatments in Patients With Critical Limb Ischemia
The principal research question is which treatment modality between open surgical, endovascular and conservative therapy is the most effective in terms of limb salvage, survival and reinterventions in patients with critical limb…
- Trial name
- CRITISCH (NCT01877252)
- Testing
- Surgical revascularization, Endovascular revascularization, No vascular intervention
- Where
- Germany
- Volunteers
- 1,200 people
- Sponsor
- St. Franziskus Hospital
Cerebral Arteriovenous Malformations
Treatment of Cerebral Arteriovenous Malformations With SQUID™ Liquid Embolic Agent
A non-interventional multicentric study for patients with a cerebral AVM for which endovascular treatment is indicated.
- Trial name
- NCT02602990
- Testing
- SQUID™
- Where
- 6 sites in Belgium, Germany
- Volunteers
- 50 people
- Sponsor
- Emboflu
Pulmonary Embolism
Endovascular Engineering ENGULF Study
Evaluation of initial safety and clinical feasibility of the Hēlo PE Thrombectomy System for thrombectomy in acute submassive pulmonary embolism (PE).
- Trial name
- ENGULF (NCT05597891)
- Testing
- Hēlo PE Thombectomy System
- Where
- 21 sites in United States
- Volunteers
- 177 people
- Sponsor
- Endovascular Engineering
Multiple Pathologies
Global Registry for Endovascular Aortic Treatment (GREAT)
Prospective, observational Registry to obtain data on device performance and clinical outcomes.
- Trial name
- GREAT (NCT01658787)
- Testing
- Endovascular aortic repair
- Where
- 6 sites in United States, Australia and 2 more
- Volunteers
- 4,600 people
- Sponsor
- W.L.Gore & Associates
Ischemic Stroke
Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke
The purpose of the study is to understand whether a new treatment of stroke - endovascular clot removal - can be added to the current standard of care to improve patient outcomes.
- Trial name
- ESCAPE (NCT01778335)
- Testing
- Endovascular thrombectomy/thrombolysis
- Where
- Canada
- Volunteers
- 316 people
- Sponsor
- University of Calgary
Mild Stroke, Acute Ischemic Stroke
Endovascular Treatment for Mild Stroke With Acute Anterior Circulation Large Vessel Occlusion
Exploring the Efficacy and Safety of Emergent Endovascular Treatment in Patients with Mild Ischemic Stroke Caused by Acute Anterior Circulation Large Vessel Occlusion based on Perfusion Imaging Screening
- Conditions
- Mild Stroke, Acute Ischemic Stroke, Endovascular Treatment, Perfusion Imaging
- Trial name
- NCT06179017
- Testing
- Experimental group:Intervention Group, Control group:best medical treatment
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhangzhou Municipal Hospital
Acute Stroke, Ischemic Stroke, Acute
Tandem Occlusion After Emergent Stenting in Acute Ischemic Stroke
In acute ischemic stroke due to tandem occlusion, the emergent stenting has recently become an endovascular treatment option combining with mechanical thrombectomy to achieve recanalization.
- Trial name
- TOESIS (NCT06120218)
- Testing
- Emergent Stenting
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Can Tho Stroke International Services Hospital
Pulmonary Embolism, Acute Pulmonary Embolism
Thrombolysis Endovascular Treatment of Pulmonary Embolism
To assess the efficacy and safety of endovascular thrombolysis of pulmonary embolism with right ventricular dysfunction with single-dose rtPA
- Trial name
- STEP (NCT03966079)
- Testing
- recombinant tissue plasminogen activator
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Acute Ischemic Stroke, ICAS - Intracranial Atherosclerosis
BASIS Technique for Endovascular Therapy of Acute Large Vessel Occlusion Strokes Due to Intracranial Atherosclerotic Disease
This study will explore the safety and efficacy of BASIS technology in ICAS-LVO lesions through a multicenter, prospective, registry, observational single-arm study.By registering intraoperative recanalization using this…
- Trial name
- NCT06881420
- Testing
- BASIS technique
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Fujian Medical University Union Hospital
Acute Ischemic Stroke
Endovascular Stroke Treatment Only (ESTO) Trial
The specific aims of this study are to: 1. Determine whether the endovascular treatment (mechanical thrombectomy) alone without using intravenous (IV) recombinant tissue plasminogen activator (rt-PA) in acute ischemic stroke…
- Trial name
- NCT04240470
- Testing
- Thrombectomy
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Missouri-Columbia
Aneurysmal Subarachnoid Hemorrhage, Endovascular Procedures
Study on Prognosis of Acutely Ruptured Intracranial Aneurysms
The SPARTA study is a prospective multicenter observational trial in the Netherlands with the aim of identifying the best clinical care in patients with aneurysmal subarachnoidal haemorrhage.
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Endovascular Procedures, Craniotomy, Patient Outcome Assessment
- Trial name
- SPARTA (NCT05851989)
- Where
- 6 sites in Netherlands
- Volunteers
- 880 people
- Sponsor
- Haaglanden Medical Centre