Clinical trials: Enhanced Recovery After Anesthesia
Acute Pain, Regional Anesthesia
Regional Analgesia in Combination With Cryoanalgesia to Prevent Acute Pain Following Nuss Procedure
Funnel chest deformation is a painful procedure, which requires high doses and long time used of opioids. It makes difficult introduction of ERAS protocol.
- Trial name
- NCT05589246
- Testing
- regional analgesia with cryolesia
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Pomeranian Medical University Szczecin
Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block
Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.
Video-Assisted thoracic surgery (VATS) is the standard treatment for localized lung cancer. However, there is no consensus on analgesic management in patients undergoing VATS.
- Conditions
- Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block, Video-Assisted Thoracic Surgery, Lung Cancer
- Trial name
- ANESSTEVATS (NCT04538235)
- Testing
- Thoracic Regional Analgesia
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Respiratory Aspiration, Hyperglycemia
Maltodextrin Versus Sugar Water Carbohydrate Loading and Gastric Volume in Geriatric Lower Limb Orthopedic Surgery
Before surgery, patients are asked to fast so the stomach is empty and stomach contents cannot enter the lungs during anesthesia. Long fasting is uncomfortable and can raise blood sugar and stress responses in older adults.
- Conditions
- Respiratory Aspiration, Hyperglycemia, Inflammation
- Trial name
- CHO-GERIGAS (NCT07872683)
- Testing
- Maltodextrin carbohydrate drink, Sugar water
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Udayana University
Cardiovascular Surgical Procedures, Pain, Postoperative
Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB…
- Conditions
- Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases
- Trial name
- NCT07557108
- Testing
- Ultrasound-Guided Pectointercostal Fascial Plane Block, Ultrasound-Guided Rectus Sheath Block, Ultrasound-Guided Recto-Intercostal Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people
- Sponsor
- Ordu University
Cesarean Section, Postoperative Recovery
Enhanced Recovery Protocol Compliance and Quality of Recovery After Cesarean Delivery
This prospective observational study will evaluate whether adherence to enhanced recovery after cesarean delivery protocols is associated with postoperative recovery quality in women undergoing elective cesarean delivery under…
- Conditions
- Cesarean Section, Postoperative Recovery, Postoperative Pain
- Trial name
- ERAC-QoR (NCT07790471)
- Testing
- Assessment of Enhanced Recovery Protocol Compliance
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bursa City Hospital
Coronary Artery Bypass, Anesthesia
Sustainable Anesthesia in Myocardial Revascularization Surgery.
Introduction: Greenhouse gases threaten the health and safety of humanity. The Declaration of Helsinki seeks to protect human health and emphasizes the urgency of implementing sustainable strategies.
- Conditions
- Coronary Artery Bypass, Anesthesia, Sustainability
- Trial name
- NCT07508865
- Testing
- Optimized recovery, Standard Anesthetic Practice
- Where
- Chile
- Volunteers
- 116 people
- Sponsor
- Universidad de La Frontera
Acute Kidney Injury (Nontraumatic), Hypotension Drug-Induced
AKI Risk Factors Analysis After Intentional Hypotensive Anesthesia
This project investigates intentionally hypotensive management such as NTG (nitroglycerin) or NTG+Trandate during general anesthesia in patients undergoing orthognathic surgery.
- Trial name
- NCT06259760
- Testing
- Nitroglycerin
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Postoperative Pain, Cardiac Surgery
ASPB-PIPB Combination in Cardiac Surgery
Cardiopulmonary bypass surgery is associated with significant postoperative pain, which may adversely affect respiratory function, delay mobilization, prolong hospital stay, and increase postoperative complications.
- Conditions
- Postoperative Pain, Cardiac Surgery, Cardiopulmonary Bypass, Median Sternotomy
- Trial name
- NCT07716943
- Testing
- Combined ASPB and PIPB, Anterior Serratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Enhanced Recovery After Surgery, Anesthesia
Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery
Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our…
- Conditions
- Enhanced Recovery After Surgery, Anesthesia, Surgery-Complications, Colorectal
- Trial name
- NCT06065696
- Testing
- Early mobilization, No early mobilization
- Where
- Indonesia
- Volunteers
- 343 people
- Sponsor
- Universitas Indonesia
Pulmonary Nodules, Early Stage Lung Cancer (I and II)
Tubeless Strategy for Enhanced Recovery After Sublobar Resection
This is a prospective, randomized controlled clinical trial conducted at a single center. The study aims to evaluate whether a "tubeless" strategy can enhance recovery for patients undergoing minimally invasive thoracoscopic…
- Conditions
- Pulmonary Nodules, Early Stage Lung Cancer (I and II), Thoracoscopic Surgery, Sublobar Resection
- Trial name
- NCT07409129
- Testing
- Laryngeal Mask Airway, Thoracic Paravertebral Block with Local Anesthetic, Non-intubated Anesthesia
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Surgery, Anesthesia
Compliance With Enhanced Recovery After Surgery Protocol (ERAS) in Surgical Patients
The concept of "enhanced recovery" was introduced by European anesthesiologists and surgeons who challenged traditional clinical practices involved in peri-operative care in 1990s.
- Trial name
- NCT03968666
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Augusta University
Pediatric Anesthesia, Pediatric Postoperative Recovery
Turkish Adaptation of the Pediatric Quality of Recovery Scale (PedSQoR-T)
This multicenter prospective observational study aims to culturally adapt the Pediatric Quality of Recovery Scale into Turkish and to evaluate the validity and reliability of the Turkish version in pediatric surgical patients.
- Conditions
- Pediatric Anesthesia, Pediatric Postoperative Recovery, Pediatric Enhanced Recovery After Surgery
- Trial name
- PedSQoR-T (NCT07527546)
- Testing
- Observational exposure
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain Management, Colorectal Surgery
Opioid-Free Anesthesia in Colorectal Surgery, 2025 (OFA-CRC-2025)
This study wants to find out if using a pain control method without opioids (Opioid-Free Anesthesia or OFA) works as well as or better than standard anesthesia (which uses opioids) for adults having minimally invasive…
- Conditions
- Pain Management, Colorectal Surgery, Opioid Free Anesthesia, Postoperative Complications
- Trial name
- OFA-CRC-2025 (NCT07771049)
- Testing
- Opioid-Free Anesthesia (OFA), Opioid-Based Anesthesia (OBA)
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Hospital Universitario La Fe
Esophageal Cancer, Complication, Postoperative
The Effects on Major Organ Complications on Esophagectomy of New Anesthetic ERAS Strategy: a Prospective Investigation
The goals of this study are to testify the effectiveness on enhancement recovery by new anesthetic ERAS (Enhanced recovery after surgery) strategy.
- Conditions
- Esophageal Cancer, Complication, Postoperative, Anesthesia
- Trial name
- ERAS (NCT03176680)
- Testing
- Fluid therapy optimization
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Fraily, Abdominal Surgery
Awareness Neuraxial Versus General Anesthesia in Frail Patients Undergoing Laparoscopic or Robotic Abdominopelvic Surgery.
This is a bicentric, prospective, non-pharmacological, randomized study designed to compare the efficacy and safety of awake neuraxial anesthesia with sedation versus general anesthesia in frail patients undergoing elective major…
- Conditions
- Fraily, Abdominal Surgery, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- SAFE-AWARENESS (NCT07486336)
- Testing
- Neuraxial anesthesia, General Anesthesia, avoidance of GABAergic-drugs strategy
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Narcotics, Recovery Quality
Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy
Laparoscopic sleeve gastrectomy is widely employed nowadays. Multimodal analgesia approach is implemented within the enhanced recovery protocol in our facility to improve participants' recovery.
- Conditions
- Narcotics, Recovery Quality, Analgesia, Bariatric Surgery
- Trial name
- NCT04285255
- Testing
- Fentanyl, Ketamine, Dexmedetomidine Injection [Precedex]
- Where
- Saudi Arabia
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Al Mashfa Medical Center
CABG, Dexmedetomidine
Role of Opioid Free Anaesthesia in Elderly Patients Undergoing Elective Coronary Artery Bypass Graft Surgeries With Cardiopulmonary Bypass in Enhanced Recovery After Surgeries
The introduction of synthetic opioids in 1960 to general anesthesia together with sedative hypnotics and muscle relaxants allowed the appearance of the concept of multimodal balanced anesthesia.
- Conditions
- CABG, Dexmedetomidine, Ketamine, Opioid Free Anesthesia
- Trial name
- NCT07360327
- Testing
- Opioid free anesthesia, Opioid based Anesthesia
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Knee Arthropathy
Persistent Post Surgical Pain After Total Knee Arthroplasty
Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this…
- Trial name
- NCT06182059
- Testing
- continuous peripheral nerve block
- Where
- Italy
- Volunteers
- 436 people
- Sponsor
- Policlinico di Monza SpA
Analgesics, Opioid
Benefits of Opioid Free Anesthesia on Morphine Consumption in Gastric Bypass
Opioid free anesthesia is a recent anesthesia technique with the aim to avoid peroperative use of morphinics to allow a diminution of secondary morphinics effects in the postoperative period.
- Trial name
- NCT05004519
- Testing
- Dexmedetomidine Injection [Precedex], Remifentanil
- Where
- Belgium
- Volunteers
- 183 people
- Sponsor
- matthieu clanet