Clinical trials: Environment Related Disease
Environmental-Pollution-Related Condition
Characterization of a Population Living in Highly Contaminated Settlement in Campania Region
some areas in the Campania region (southern Italy) have attracted media coverage in the past 15 years, and are considered a dramatic example of an extremely polluted area.
- Trial name
- SPES (NCT05976126)
- Testing
- Determination of dioxins (PCDD/Fs), polychlorinated biphenyls (PCBs) and trace elements
- Volunteers
- 4,227 people, healthy volunteers welcome
- Sponsor
- Francesca De Filippis
Adolescent Behavior
Randomized Trial of a Social Networks Intervention
Advancement via Individual Determination (AVID) is a college preparatory program that provides a unique opportunity to determine whether schools can reduce substance use by re-grouping at-risk students with high-performing…
- Trial name
- AVID (NCT03059433)
- Testing
- AVID Intervention
- Where
- United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Problems Related to Social Environment
Leveraging Regulatory Flexibility for Methadone Take-Home Dosing to Improve Retention in Treatment for Opioid Use Disorder
Using a stepped-wedge randomized controlled trial, the study will test whether a clinic-level multidimensional intervention conducted in 36 opioid treatment programs (OTPs) will improve clinical decision making, regulatory…
- Trial name
- NCT05675735
- Testing
- Clinic-Level Multidimensional Intervention
- Where
- 4 sites in United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Obesity, Overweight (BMI > 25)
Mapping Obesity-related Subtypes And Interconnected Clusters
In the Netherlands, about half of all adults are currently living with overweight. This number is expected to rise to as much as 64% by the year 2050, especially among younger adults aged 18 to 44.
- Trial name
- MOSAIC (NCT06960434)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Zuyd University of Applied Sciences
Bipolar Disorder, Attention Deficit Disorder With Hyperactivity
Juvenile Bipolar Disorder Outpatient Program
This is an outpatient program for children and adolescents with bipolar disorders. The naturalistic approach of the program will allow a proper investigation of the disorder, assessment of environmental and biological factors…
- Trial name
- ProCAB (NCT01000402)
- Testing
- Psychopharmacotherapy
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Schizophrenia, Bipolar Disorder
Time and Virtual Reality in Schizophrenia and Bipolar Disorder
Patients with bipolar disorders report an acceleration or slowing of time flow, and patients with schizophrenic spectrum disorders a time fragmentation. These disorders would be linked to disorders of the sense of self.
- Trial name
- VirtualTimes (NCT04432116)
- Testing
- virtual reality 1, virtual reality 2
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Body Temperature Changes, Heat Stress
Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part III
Occupational heat stress directly threatens workers' ability to live healthy and productive lives. Heat exposed workers are at an elevated risk of experiencing impaired work performance and cognitive function leading to a greater…
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT06630832
- Testing
- Simulated work in the heat with no cooling during rest breaks, Simulated work in the heat with partial cooling during rest breaks, Simulated work in the heat with full cooling during rest breaks
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Bipolar Disorder, Circadian Rhythm
Effects of Sex Hormones on Circadian Rhythm in Men and Women
For many years researchers have been trying to better understand the regulation of sleep and activity by studying circadian (daily) rhythms of human beings.
- Conditions
- Bipolar Disorder, Circadian Rhythm, Depressive Disorder
- Trial name
- NCT00001285
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Arsenic Poisoning, Environmental Exposure
Table-Top Water Pitcher to Reduce Arsenic Exposure Among Well Users in New Hampshire
The goals of this clinical trial are to: 1. gather preliminary data on the effectiveness of a table-top water pitcher filtration system in reducing arsenic exposure among individuals using private wells with elevated (>5 μg/L)…
- Conditions
- Arsenic Poisoning, Environmental Exposure, Water-Related Diseases
- Trial name
- NCT07103356
- Testing
- Water Pitcher Filtration System
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Nurses' Work Environment, Committed Centers With Excellence in Care (CCEC®) Program
Impact of Good Practice Guidelines on Evidence-based Practice and Nurses' Work Environment
Evidence-based practice (EBP) has improved patient health outcomes. The work environment of nurses is a key element to improving the quality of care and to facilitate EBP, while also improving health outcomes.
- Conditions
- Nurses' Work Environment, Committed Centers With Excellence in Care (CCEC®) Program, Nurses' Evidence-based-practice Attitudes, Nurse Physician Relations
- Trial name
- NCT04199065
- Testing
- Good Practice Guidelines implementation
- Where
- 17 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Heathly Subjects, Primary Health Care
Assessing the Effectiveness of Heat Adaptation Digital Messages From Primary Care Providers to Their Patients on the Change in Behaviour for Heatwave-related Preparedness
Extreme heat events pose a significant health threat in Canada, as demonstrated by the 2021 heat wave that claimed over 600 lives in Western Canada. Most heat-related deaths occur indoors and are preventable.
- Conditions
- Heathly Subjects, Primary Health Care, Climate Change, Public Health
- Trial name
- HeatSmart (NCT07024628)
- Testing
- Heat adaptation digital messaging, Non-heat-related digital messaging
- Where
- Canada
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Hopital Montfort
Post Traumatic Stress Disorder
Effect of Exercise on Post-traumatic Growth Among Health Care Providers With Post-traumatic Stress
The purpose of designing this randomized control trial is to observe the effect of nature-based walk on post-traumatic growth and Psychophysiological alterations associated with it, in traumatic stress among health care providers…
- Trial name
- NCT04592770
- Testing
- Nature based walk therapy, Sit in nature
- Where
- Pakistan
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Major Depressive Disorder (MDD), Anxiety Disorder
Identification and Molecular Characterisation of Urban-environmental Stress Patterns Affecting Mental Illness
Mental disorders have become a major contributor to the global burden of non-communicable diseases, with disability-adjusted life years (DALYs) attributable to these conditions continuing to rise.
- Conditions
- Major Depressive Disorder (MDD), Anxiety Disorder, Alcohol Use Disorder (AUD)
- Trial name
- NCT07571226
- Testing
- wearable monitoring devices
- Where
- 3 sites in China
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Complications of Prematurity
Prematurity Related Risks of Cognitive Impairment at School Age
The main purpose of this study is to better evaluate prematurely born children cognitive development at school age, with regards to birth conditions but also to social situation, intra family relationships, and modalities of…
- Trial name
- NEORIS (NCT02054507)
- Testing
- Cognitive evaluation (Wechsler IV tests)
- Where
- 2 sites in France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jean Michel Hascoet
Musculoskeletal Pain, Mental Health Wellness 1
Health in Work - a Measure for Increased Coping and Work Inclusion
Health in work - a measure for increased coping and work participation -An effect analysis of a health- and work environment intervention at the workplace.
- Conditions
- Musculoskeletal Pain, Mental Health Wellness 1, Work-Related Condition
- Trial name
- HiAforsk (NCT04000035)
- Testing
- Health and work environment information and processes
- Where
- Norway
- Volunteers
- 1,383 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Environment Related Disease
A Pilot Study Evaluating Go NAP SACC's Web-based Nutrition Tool for Child Care
The purpose of this project is to evaluate the effectiveness of Go NAP SACC (Get online with Nutrition and Physical Activity Self-Assessment for Child Care), a suite of web-based tools designed to help child care programs improve…
- Trial name
- NCT02889198
- Testing
- Go NAP SACC
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV, Substance Use
Employing eSBI in HIV Testing for At-risk Youth
The purpose of this study is to assess the feasibility, acceptability and test the initial efficacy of eSBI, (electronic screening and brief intervention for alcohol use) coupled with STTR (Seek, Test, Treat, and Retain) in…
- Trial name
- NCT02703116
- Testing
- Alcohol Use BI, Nutrition Intervention
- Where
- 3 sites in United States
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Musculoskeletal Diseases
Effects Job Rotation in the Prevention of Work Related Musculoskeletal Disorders
The objective this study is evaluated if job rotation (change works that function every to work hours)contributes to reduce absence from work to complaints musculoskeletal disorders.
- Trial name
- Jobrotation (NCT01979731)
- Testing
- Job rotation, Guidelines ergonomics
- Where
- Brazil
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Universidade Cidade de Sao Paulo
Esophageal Cancer
Genetic and Environmental Risk Factors Related to Esophageal Cancer
RATIONALE: Gathering information about genes, cigarette smoking, and diet may help doctors learn more about risk factors that may cause esophageal cancer.
- Trial name
- NCT01035398
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dementia Alzheimers, Alzheimer Disease
Person-Environment Fit for Persons With Dementia
This trial will assess feasibility of a non-pharmacological intervention for persons living with Alzheimer's disease and related dementias (ADRD) to improve behavioral and psychiatric symptoms of dementia and functional…
- Trial name
- NCT05722743
- Testing
- Harmony, National Institute on Aging Program
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Elizabeth K Rhodus