Clinical trials: Epistaxis
Epistaxis
Hemoglobin and INR Out of Nose Blood
Nose bleeding (epistaxis) is a common emergency. It is often difficult to estimate blood loss and the current hemoglobin of patients. In patients with oral anticoagulation, it is important to measure the level of hemodilution.
- Trial name
- NCT02370381
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Anterior Epistaxis
Topical 15% Trichloroacetic Acid Versus Silver Nitrate Cauterization in the Management of Idiopathic Childhood Epistaxis: A Prospective Double-Blinded, Randomized Clinical Trial
the invistigators aim to explore the efficacy of trichloroacetic acid as a chemical cauterization agent and compare it with that of silver nitrate in the treatment of idiopathic epistaxis in children.
- Trial name
- Epistaxis (NCT06836791)
- Testing
- chemical cautrizating agents to stop epistaxis, Silver Nitrate, Trichloroacetic Acid Topical
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Youssef Zaki
Epistaxis
Xylometazoline and Cocaine for Nasal Vasoconstriction
The objective of this study is to compare xylometazoline and cocaine's effect on minimizing epistaxis when administered as a local vasoconstrictor prior to nasal intubation.
- Trial name
- NCT05334017
- Testing
- Xylometazoline 0,1%, Cocaine 4%
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Epistaxis, Nasal Obstruction
The Effect of Packing in Post Operative Management of FESS
Chronic sinusitis is a very common problem. The functional endoscopic sinus surgery is a prevalent option to treat this disease.During usage of different techniques of surgery, the need for packing after surgery is debatable…
- Conditions
- Epistaxis, Nasal Obstruction, Pain
- Trial name
- NCT00793117
- Testing
- packing
- Where
- Iran
- Volunteers
- 66 people
- Sponsor
- Tehran University of Medical Sciences
Nasotracheal Intubation
Effect of Nose Selection Using Rhnoscope on Epistaxis of Nasotracheal Intubation
Rhinoscope is useful to exam intranasal structure. This information could be utilized to select more suitable nose for nasotracheal intubation.
- Trial name
- NCT04164836
- Testing
- rhinoscope
- Where
- South Korea
- Volunteers
- 182 people
- Sponsor
- Ajou University School of Medicine
Hereditary Hemorrhagic Telangiectasia, Epistaxis
Treatment of Nasal Staphylococcus Aureus Colonization in Patients With HHT
Compare the frequency of epistaxis and quality of life related to nasal bleeding in patients with HHT colonized with sataphylococo before and after being treated with mupirocin ointment.
- Trial name
- NCT02963129
- Testing
- Mupirocin
- Where
- 2 sites in Argentina
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Telangiectasia, Hereditary Hemorrhagic
Pomalidomide for the Treatment of Bleeding in HHT
This is a Phase II placebo-controlled double-blind study of pomalidomide in patients with hereditary hemorrhagic telangiectasia (HHT) with moderate to severe epistaxis who have anemia and/or require parenteral iron infusions or…
- Trial name
- PATH-HHT (NCT03910244)
- Testing
- Pomalidomide Oral Product
- Where
- 14 sites in United States
- Volunteers
- 145 people
- Sponsor
- The Cleveland Clinic
Hereditary Hemorrhagic Telangiectasia, Epistaxis
Efficacy of Thalidomide in the Treatment of Hereditary Hemorrhagic Telangiectasia
Hereditary hemorrhagic telangiectasia (HHT) (OMIM 187300 and 600376), also known as Rendu-Osler-Weber syndrome, is an autosomal dominant disease and has a prevalence between 1:5000 and 1:8000 in different populations.
- Trial name
- THALI-HHT (NCT01485224)
- Testing
- Thalidomide
- Where
- Italy
- Volunteers
- 31 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Nasal Obstruction, Rhinitis, Vasomotor
Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer
The purpose of this study is to learn whether nasal saline irrigation is beneficial to patients undergoing radiation therapy for oropharyngeal cancer.
- Conditions
- Nasal Obstruction, Rhinitis, Vasomotor, Epistaxis
- Trial name
- NCT02338102
- Testing
- Saline mixture
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Lisa Shnayder
Nasotracheal Intubation, Nasal Bleeding
Nasotracheal Intubation Over a Bougie
The purpose of this study is to determine whether nasal intubation over a bougie placed via a nasal trumpet will decrease nasal trauma when compared to the conventional technique of blind nasal endotracheal tube passage.
- Trial name
- NCT03003455
- Testing
- Nasotracheal intubation over a bougie, Conventional Nasotracheal Intubation
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Epistaxis
Minimally Invasive Control of Epistaxis (MICE)
Epistaxis is a common disorder with 60% of the population suffering from one episode and 10% of these cases requiring medical attention.
- Trial name
- MICE (NCT00666471)
- Testing
- MICE, SPA ligation
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Calgary
Bleeding Nose
Nebulized Tranexamic Acid in Sinus Surgery
The results of several recent studies on endoscopic sinus surgery through topical administration of tranexamic acid are encouraging in terms of the efficacy of tranexamic acid for intraoperative bleeding and other pathological…
- Trial name
- NCT04905901
- Testing
- Tranexamic acid
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Hemorrhagic Hereditary Telangiectasia (HHT)
Efficacy and Safety of a 0.1% Tacrolimus Nasal Ointment as a Treatment for Epistaxis in Hemorrhagic Hereditary Telangiectasia (HHT)
The recognized manifestations of HHT are all due to abnormalities in vascular structure. Epistaxis due to telangiectases formation is spontaneous, very variable, recurrent in 90% of patients, and associated with severe anemia in…
- Trial name
- TACRO (NCT03152019)
- Testing
- Protopic® (Tacrolimus) 0.1% ointment
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Epistaxis, Analgesia
The Effect of Local Anesthesia With Lidocaine During Insertion and Removal of Nasal Packing
This study aims to investigate the effect of local nasal anesthesia with lidocaine spray on the insertion of nasal tampons during active nasal bleeding.
- Trial name
- NCT04519463
- Testing
- Xylocaine Mucosal Product
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muhamed Masalha
Computed Tomography-guided Nasotracheal Intubation, The Space Where the Tube Will be Passed in the Internal Nasal Valve Region
Computed Tomography-Guided Nasotracheal Intubation Procedure
Background: Nasotracheal intubation can lead to severe complications like epistaxis with excessive bleeding. The advancement difficulty of the tube faced during nasal intubation is one of the fundamental causes of this condition.
- Trial name
- NCT05525754
- Testing
- computed tomography-guided nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Epistaxis
Management of Persistent Epistaxis Using Floseal Hemostatic Matrix
Nosebleeds that persist even after adequate traditional nasal packing may require aggressive treatment strategies to stop bleeding.
- Trial name
- NCT02488135
- Testing
- Floseal Hemostatic Matrix, Traditional Nasal Packing
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Alberta
Cardiovascular Disease, Epistaxis
Correlation Between Epistaxis and Cardiovascular Disease
Investigators examine blood-pressure variance, several cardiovascular risk factors of patient with epistaxis. As a result of collected data, investigators look into correlation between epistaxis and hypertensive cardiovascular…
- Trial name
- CBECD (NCT02677467)
- Testing
- Blood-pressure variability
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hanyang University
HHT, Hereditary Hemorrhagic Telangiectasia
Intranasal Bevacizumab for HHT-Related Epistaxis
This is a randomized, controlled, double-blind, placebo-controlled trial of intranasal Avastin (bevacizumab) injection versus saline control for control of HHT-related epistaxis when used in conjunction with bipolar…
- Conditions
- HHT, Hereditary Hemorrhagic Telangiectasia, Epistaxis, Nose Bleeds
- Trial name
- NCT02389959
- Testing
- Bevacizumab
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Anterior Epistaxis, Tranexamic Acid
Tranexamic Acid Dosage for Topical Treatment of Anterior Epistaxis
Patients with epistaxis usually apply to the emergency department for initial treatment. According to recent research, tranexamic acid is effective in the treatment of epistaxis.
- Trial name
- Tranexamicacid (NCT06183918)
- Testing
- Tranexamic acid, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Izmir Ataturk Training and Research Hospital
Epistaxis
Trial of a Novel Chitosan Hemostatic Sealant in the Management of Complicated Epistaxis
Purpose: This study is a prospective clinical trial to investigate the efficacy of a chitosan-coated nasal packing (ChitoFlex® used in conjunction with the HemCon Nasal Plug) in the management of difficult spontaneous epistaxis…
- Trial name
- NCT00863356
- Testing
- 2009-I-Epistaxis-1
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HemCon Medical Technologies, Inc