Clinical trials: Error, Refractive
Myopia
An Evaluation of Outcomes Following Wavefront Optimized or Wavefront Guided Lasik Procedure in Low to Moderate Myopic Patients
To compare post-surgical outcomes in patients who have undergone Wavefront Guided LASIK (iLASIK platform) compared with patients who have undergone Wavefront Optimized LASIK (Wavelight Allegretto 400 Hz platform).
- Trial name
- NCT01173198
- Testing
- WAVEFRONT Optimized LASIK, WAVEFRONT GUIDED LASIK
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Innovative Medical
Near Vision, Refractive Error Correction
Clinical Outcomes of the Use of a Femtosecond Laser Treatment in a Patient With Implanted Monofocal IOLs
This study aims to assess the safety and efficacy of evaluating near vision or refractive error in eyes implanted with a mono focal intraocular lens (IOL) using a low-energy femtosecond laser.
- Trial name
- NCT07447622
- Testing
- Device
- Where
- Czechia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Myopia
Comparing Silicone Hydrogel Contact Lens Wearers to Hydrogel Contact Lens Wearers and Non-lens Wearers
This study was a multi-site, prospective, randomized, non-masked, unilateral, non-dispensing study.
- Trial name
- NCT04886479
- Testing
- Control, Test Lens
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Error
Clinical Evaluation of ACUVUE® OASYS® 1-Day and ACUVUE® OASYS®
The purpose of this study is to evaluate the performance of two commercially-available silicone hydrogel contact lenses in normal and low humidity environments after at least 7 days of wear.
- Trial name
- NCT02696317
- Testing
- Senofilcon A contact lenses with HydraLuxe™, Senofilcon A contact lenses
- Volunteers
- 84 people
- Sponsor
- Alcon Research
Presbyopia
A Study to Assess the Impact and Adverse Events of Topical Eyedrops of AGN-190584 on Night-driving Performance in Participants, 40 to 55 Years of Age
The purpose of this study is to evaluate night-driving performance in real-world driving conditions in participants with presbyopia treated with AGN-190584 versus vehicle.
- Trial name
- NCT04837482
- Testing
- AGN-190584, Vehicle
- Where
- Australia
- Volunteers
- 43 people
- Sponsor
- AbbVie
Presbyopia
Intrastromal Presbyopia Correction by Means of a Femtosecond Laser
This clinical study is an open, prospective, multi-centre eye study consisting of three study arms to determine the safety and efficacy of intrastromal incisions for the correction of visual acuity on presbyopic eyes.
- Trial name
- NCT01025050
- Testing
- Intrastromal Correction of Presbyopia
- Where
- 4 sites in Germany
- Volunteers
- 58 people
- Sponsor
- Technolas Perfect Vision GmbH
Myopia
Binocular Peripheral Myopic Defocus Using a Clinical Prototype Device
Kubota Vision Inc. has developed a spectacle-like prototype device which is designed to be used as a light-based therapy to reduce myopia progression.
- Trial name
- NCT05425108
- Testing
- Binocular CP1
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Kubota Vision Inc.
Presbyopia
Evaluation of the Performance of Investigational Contact Lenses in a Presbyopic Population
The objective of this study is to evaluate the performance of a novel multifocal lens system.
- Trial name
- NCT01763047
- Testing
- etafilcon A, lotrafilcon B
- Where
- 19 sites in United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Evaluating Two Multifocal Daily Disposable Contact Lenses
The objective of the study was to adapt existing multifocal soft lens wearers to a Control Lens for at least 2 weeks and then evaluate the success of switching them to the Test Lens, with a review after 2 weeks.
- Trial name
- NCT05579886
- Testing
- Control Lens, Test Lens
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Evaluation of Hydrogels vs Silicone Hydrogel Contact Lenses
The aim of this fitting study is to evaluate the clinical performance of different hydrogel and silicone hydrogel contact lenses.
- Trial name
- NCT01966770
- Testing
- Pair 1 (ocufilcon D / ocufilcon D), Pair 2 (ocufilcon D / enfilcon A), Pair 3 (ocufilcon D / comfilcon A)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Gas Permeable Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in gas permeable lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912781
- Testing
- FID 120947A contact lens disinfecting solution, Boston Simplus multi-action solution, Gas permeable contact lenses
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Cataract, Presbyopia
Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens
The purpose of this study is to determine the safety and effectiveness of the IC-8 IOL implanted in one eye and a monofocal or monofocal toric IOL implanted in the fellow eye in accordance with the indication.
- Trial name
- NCT03633695
- Testing
- IC-8 IOL Group, Control Group
- Where
- 21 sites in United States
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Refractive Errors, Astigmatism
Clinical Comparison of 2 Daily Disposable Toric Soft Contact Lenses
The purpose of this study to evaluate the overall performance of PRECISION1™ for Astigmatism contact lenses with MyDay® Toric contact lenses.
- Trial name
- NCT05039112
- Testing
- Verofilcon A toric contact lenses, Stenfilcon A toric contact lenses
- Where
- 6 sites in United States
- Volunteers
- 64 people
- Sponsor
- Alcon Research
Aphakia, Presbyopia
Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs
This is a prospective, multicenter, post-approval active surveillance study. The purpose of this study is to report the rate of post-surgical intraocular inflammation (based upon a specified case definition) reported within a…
- Conditions
- Aphakia, Presbyopia, Astigmatism
- Trial name
- NCT03733730
- Testing
- ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 2,449 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
Clinical Performance of Habitual Wearers of Bioclear 1-day Lenses When Refitted With Biomedics 1-day Extra for 1 Week
Open label, 1-week daily disposable, dispensing study
- Trial name
- NCT02406495
- Testing
- filcon IV 1, ocufilcon D
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Myopia
A Clinical Evaluation of Two Contact Lenses Used With Three Care Systems
The objective of the study was to compare the clinical performance of the two contact lenses when used in combination with three care systems.
- Trial name
- NCT04195581
- Testing
- comfilcon A, fanfilcon A
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Contact Lens Trial Fitting Experience
This study will assess a trial fitting experience with contact lenses.
- Trial name
- NCT07600645
- Testing
- Lens A ( stenfilcon A )
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia
Compare Visual Outcomes Using a New Diagnostic Device
Evaluation of preoperative corrected distance visual acuity (CDVA) obtained with VirtIOL device compared to postoperative CDVA.
- Trial name
- NCT04037631
- Testing
- Diagnostic device
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Lens Opacities
PMCF Study on Monofocal Toric IOL (PODEYE TORIC)
This is a single-center, prospective, open-label PMCF study whereby patients undergoing routine cataract surgery will have mono- or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2101 (NCT04744467)
- Testing
- IOL implantation experimental
- Where
- Czechia
- Volunteers
- 12 people
- Sponsor
- Beaver-Visitec International, Inc.
Ametropia
Clinical Characterization of Symptomatic Populations
This is an unmasked, non-randomized, single arm, stratified, dispensing investigation of symptomatic and asymptomatic subject populations.
- Trial name
- NCT03319212
- Testing
- senofilcon A contact lenses
- Where
- 2 sites in United States, Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.