Clinical trials: Etiology
Virtual Reality, Acute Pain
Virtual Reality Experiences on Acute Pain and Distress
The aim of this study is to evaluate the efficacy of virtual reality experiences on acute pain and distress caused by fluoroscopic pain intervention in chronic pain patient.
- Conditions
- Virtual Reality, Acute Pain, Anxiety
- Trial name
- NCT03599479
- Testing
- Virtual reality group
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University
Bacteria Infection Mechanism
Cryptic Bacteria of the Thyroid Tissue as a Possible Cause of the Pathology of This Organ
The presence of cryptic microbes has been widely documented in animal healthy deep tissues. The thyroid gland is an organ specifically exposed to the microbial environment due to its close location to the mouth microbiome.
- Trial name
- NCT04552496
- Where
- 2 sites in Poland
- Volunteers
- 120 people
- Sponsor
- Centre of Postgraduate Medical Education
Status Epilepticus
A Clinical Study of Children With Status Epilepticus in China
Phase 1: The first part of study is a multi-center, retrospect study involving 38 hospitals. The program is a national epidemiological study on status epilepticus in Chinese children.The aims of the epidemiological study include…
- Trial name
- NCT03378687
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Fudan University
To Investigate the Incidence and Causes of Awareness During General Anesthesia, To Investigate the of Dreaming During Anesthesia
İntraoperative Awareness Under General Anesthesia
Intraoperative awareness which means the recall of experiences recorded in patients' memories during general anesthesia in the postoperative period is an important issue in anesthesia practice.
- Conditions
- To Investigate the Incidence and Causes of Awareness During General Anesthesia, To Investigate the of Dreaming During Anesthesia, To Investigate the Intra-operative Experiences of Patients Who Report Awareness, To Investigate the Risk Factors That May be Associated With Awareness
- Trial name
- NCT04697732
- Testing
- General anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 30,000 people
- Sponsor
- Baskent University Ankara Hospital
Liver Failure
Umbilical Cord Mesenchymal Stem Cells Transplantation Combined With Plasma Exchange for Patients With Liver Failure
Liver failure (LF) is a dramatic clinical syndrome with massive necrosis of liver cells. Although liver transplantation provides an option to cure patients suffering with LF, lack of donors, postoperative complications…
- Trial name
- NCT01724398
- Testing
- Conventional plus UC-MSC treatment, Conventional plus PE treatment, Conventional plus UC-MSC and PE therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
COVID-19
"Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of the Drug B10-FC After Single Administration to Adult Patients".
A two-stage open-label, prospective, safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity study with participation of healthy volunteers in three dose-escalation groups and patients with a confirmed…
- Trial name
- NCT07156864
- Testing
- 1/10 therapeutic dose, 1/2 therapeutic dose, full therapeutic dose
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Systemic Inflammatory Response, Aortic Valve Stenosis
Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement
Aim of this randomized prospective study is to investigate the immunomodulatory effects of dexmedetomidine on outcomes in patients with isolated aortic stenosis after surgical aortic valve replacement.
- Trial name
- NCT05641064
- Testing
- Dexmedetomidine 0.5mcg/kg/h, Dexmedetomidine 1 mcg/kg/h
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Dubrava
Misadventure During Injection / Vaccination
The Effect of Stress Ball Use on Procedural Pain Caused by Subcutaneous Injection in Orthopedic Patients
Randomization in the study will be done by the researchers with the Randomizer Research program. The research will be carried out between 01.01.2023 and 01.10.2023 with the participation of 134 patients who were hospitalized in…
- Trial name
- NCT06023485
- Testing
- stress ball use during subcutaneous injection
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Cholecystectomy
Evaluation of Microbial Colonisation and Contamination Caused by the Transvaginal and Transabdominal Access for Cholecystectomy
Transvaginal hybrid procedures are of interest as an available NOTES procedure for the clinical routine. The gynaecologists' experiences and the available studies report on low morbidity related to the transvaginal access.
- Trial name
- NOBACT (NCT01078025)
- Testing
- Smear test vaginally, intraabdominally
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Cantonal Hospital of St. Gallen
Tinnitus, Hearing Disorders
Evaluation of Potential Causes of Nap Modulated Tinnitus
The proposed research is a non-interventional study made to evaluate different measurements on 1 group of participants, before and after taking a nap, aiming to potentially guide future investigations on nap-modulated tinnitus to…
- Conditions
- Tinnitus, Hearing Disorders, Ear Diseases, Otorhinolaryngologic Diseases
- Trial name
- TinniNap (NCT05467059)
- Testing
- Napping
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Robin Guillard EIRL
Progression of Rheumatoid Arthritis, Osteoarthritis of Multiple Joints
To Examine Whether or Not the Primary Causes of OA or RA Might be Bone Alterations
Generally, osteoarthris (OA) is considered as primarily cartilage disease. However, as we and others have previously reported, a portion of OA might be caused primarily by bone alterations.
- Trial name
- NCT02327650
- Testing
- The examinations for bones in joints of OA and RA patients
- Where
- 2 sites in Japan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Dyspareunia
Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia
The objective of this community-based, non-randomized, quasi-experimental study is to assess the effectiveness of BTL EXILIS technology-based on combined radiofrequency and ultrasound-in women of childbearing age from an…
- Trial name
- NCT07504991
- Testing
- Combining radiofrequency and ultrasound. BTL Exilis
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Cardiovascular Diseases, Respiratory Diseases
Need for the Assessment and Consultation Team (ACT) Following Anesthetic Care
The goal of this study was to identify the etiology of events and demographics of patients that experience complications requiring activation of the Rapid Response Team (RRT) during the first 24 h following anesthetic care.
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Neurologic Diseases
- Trial name
- NCT02754947
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Nationwide Children's Hospital
Out-of-Hospital Cardiac Arrest
EMERGEncy Versus Delayed Coronary Angiogram in Survivors of Out-of-hospital Cardiac Arrest
Sudden cardiac death (SCD) remains a major public health issue with a low survival rate. The most common cause of SCD is acute coronary artery occlusion.
- Trial name
- EMERGE (NCT02876458)
- Testing
- Immediate coronary angiogram, Delayed coronary angiogram
- Where
- France
- Volunteers
- 336 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson's Disease
Combined Genome and RNA Sequencing for Genetic Diagnosis of Parkinsonism
Despite the increasing availability and advances in the analysis of high-throughput DNA sequencing, the majority of patients with early-onset or familial parkinsonism remain without a molecular diagnosis.
- Trial name
- ParkOmic (NCT06576713)
- Testing
- Combiner whole genome and RNA sequencing
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Healthy
Safety and Efficacy of NT 201, Free of Complexing Proteins, in the Treatment of Glabellar Frown Lines
NT 201 is a Botulinum toxin type A preparation free of complexing proteins. Injected into the muscle, NT 201 causes a reversible local relaxation of the injected muscle.
- Trial name
- NCT00694148
- Testing
- NT 201
- Where
- Germany
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Leukodystrophy, Leukoencephalopathy
The Nosology and Etiology of Leukodystrophies of Unknown Causes
Background: A leukodystrophy is a disease affecting the white matter of the brain. The white matter conducts electricity from one part of the brain to the other.
- Trial name
- NCT00889174
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Infertility, Intrauterine Adhesions
Treatment of Infertility by Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchyma Stem Cells
Study of the treatment of infertility caused by recurrent intrauterine adhesions (IUA) by collagen scaffold loaded with umbilical cord derived mesenchymal stem cells (UC-MSCs) to provide clinical evidence of safety and…
- Trial name
- NCT02313415
- Testing
- UC-MSCs therapy
- Where
- China
- Volunteers
- 26 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Rare Disease, Idiopathic Disease
Idiopathic Diseases of Man
This research is being done to learn more about possible genetic causes of currently undiagnosed conditions, and to find out how the development of new technologies, such as DNA sequencing, can increase knowledge of the role…
- Trial name
- IDIOM (NCT01440218)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Scripps Translational Science Institute
Clopidogrel
Does Continued Use of Clopidogrel Into Surgery Cause Increased Perioperative Bleeding?
Patients who on taking clopidogrel are randomized to either continue clopidogrel into general surgery or discontinue clopidogrel 7 days before surgery. All patients resume clopidogrel after surgery.
- Trial name
- NCT01960296
- Testing
- Clopidogrel, Discontinue Clopidogrel
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
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