Clinical trials: Etiology
COVID-19 Pandemic, Morality
Evaluation of Corticosteroids Use and Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Study
Despite the recommendations to avoid using corticosteroids systematically for hospitalized coronavirus disease of 2019 (COVID-19) patients, healthcare professionals used personalized treatments, including corticosteroids, as…
- Trial name
- NCT05844410
- Testing
- Corticosteroid
- Where
- Lebanon
- Volunteers
- 422 people
- Sponsor
- Lebanese University
Undiagnosed Diseases, Cardiovascular Disease
Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)
Background: Studies show that rare genetic variants might lead to diseases. Researchers want to collect blood and tissue samples so they can study them and better understand diseases.
- Trial name
- NCT02543996
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome, Myocardial Infarction
Rule Out Myocardial Infarction by Computer Assisted Tomography
The goal of this research is to determine noninvasively whether detection of coronary stenosis and plaque by multidetector computed tomography (MDCT) in patients with acute chest pain suspected of acute coronary syndrome (ACS)…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Unstable Angina Pectoris
- Trial name
- ROMICAT (NCT00990262)
- Testing
- Cardiac Computed Tomography
- Where
- United States
- Volunteers
- 368 people
- Sponsor
- Massachusetts General Hospital
Out-Of-Hospital Cardiac Arrest
Differential Diagnosis and Cause-specific Treatment During OHCA
Differential diagnosis: ultrasound, blood gas analyse combined with examination of the patient and environment is used during Out Of Hospital Cardiac Arrest (OHCA) to screen possible underlying cause of cardiac arrest.
- Trial name
- NCT04670354
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Cancer-related Problem/Condition, Head and Neck Cancer
S9908: Glutamine in Treating Mucositis Caused by Radiation Therapy in Patients With Newly Diagnosed Cancer of the Mouth or Throat
RATIONALE: Glutamine may be effective in decreasing side effects, such as inflammation of the mouth and throat, caused by radiation therapy. The effectiveness of glutamine for mucositis is not yet known.
- Conditions
- Cancer-related Problem/Condition, Head and Neck Cancer, Pain
- Trial name
- NCT00006994
- Testing
- glutamine, radiation therapy
- Where
- 107 sites in United States, Canada
- Volunteers
- 23 people
- Sponsor
- SWOG Cancer Research Network
Infant, Pain
Kangaroo Care Reduces Infant Pain Caused By Vaccination
The aim of this randomized controlled study determine the effect of KMC on pain in infants during vaccination.
- Conditions
- Infant, Pain, Kangaroo Mother Care, Nursing
- Trial name
- NCT04596137
- Testing
- İnfant pain management
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Invasive Group A Beta-Haemolytic Streptococcal Disease
Invasive Disease Caused by Group A Streptococcus (GAS) (DICAR)
The goal of this study is to gain important knowledge on the pathogenesis and prognostic factors in severe invasive group A streptococcal (GAS) infections, as well as the effects of individual characteristics of both the pathogen…
- Trial name
- DICAR (NCT03507101)
- Testing
- No intervention
- Where
- 2 sites in Finland
- Volunteers
- 45 people
- Sponsor
- Tampere University Hospital
Nausea and Vomiting
Efficacy of Three Antiemetics in Preventing Nausea and Vomiting
To explore the effect of commonly used antiemetic drugs on reducing nausea and vomiting caused by intravenous tramadol injection, so as to reduce the incidence of nausea and vomiting in clinical use of tramadol and provide…
- Trial name
- NCT05533281
- Testing
- tropisetron, metoclopramide, dexamethasone
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Complication of Anesthesia
Incidence and Etiology of Complications Associated With Peripheral Nerves Blocks
Procedures performed under regional anesthesia, especially peripheral nerve blocks (PNB) have increased markedly in recent decades. However, like any technical procedure, these techniques carry an implicit risk of complications.
- Trial name
- CARE (NCT05682300)
- Testing
- peripheral nerve block
- Where
- Spain
- Volunteers
- 1,390 people
- Sponsor
- Hospital del Rio Hortega
Post Partum Hemorrhage
Sublingual Oxytocin for the Prevention of Post-partum Hemorrhage
An open-label, randomized, single-center, dose ascending trial will be conducted to evaluate the efficacy and safety of sublingual oxytocin for the prevention of post-partum hemorrhage caused by uterine atony in term pregnant…
- Trial name
- NCT06968481
- Testing
- Oxytocin sublingual, Oxytocin IM
- Where
- Nigeria
- Volunteers
- 330 people
- Sponsor
- Insud Pharma
Female Infertility
Endometrial Effects of Lipiodol
The goal is to investigate whether endometrial flushing with Lipiodol enhances fertility. Therefore, anatomo-pathological, histochemical and transcriptional changes of the endometrium after Lipiodol bathing in a general…
- Trial name
- NCT03542331
- Testing
- Lipiodol, Mock catheter
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Idiopathic Anaphylaxis, Drug Anaphylaxis
Cause of Unexplained Anaphylaxis
This study will explore the possible cause of unexplained, or idiopathic, anaphylaxis. Anaphylaxis is a rapid, life-threatening, severe reaction that occurs suddenly after contact with an allergy-causing substance, usually a…
- Conditions
- Idiopathic Anaphylaxis, Drug Anaphylaxis, Venom Anaphylaxis, Food Anaphylaxis
- Trial name
- NCT00719719
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Major Depression, Osteoporosis
Vitamin D, SSRIs and the Musculoskeletal System
In recent years it has become evident that some types of antidepressants are associated both with an increased risk of falling and decreased bone mineral density.
- Trial name
- NCT01932931
- Testing
- cholecalciferol (50ug)
- Where
- 2 sites in Denmark
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Coronary Artery Disease
Causation And Prognosis Analyses of Coronary Artery Diseases: A Longitudinal Cohort Study
This study is a single-center, historical prospective cohort study including patients diagnosed with coronary artery diseases, including stable angina pectoris, unstable angina pectoris, non-ST-segment elevation myocardial…
- Trial name
- CAPACITY (NCT07480512)
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- Sun Yat-sen University
Coronary Artery Disease
ABSORB II Randomized Controlled Trial
Prospective, randomized (2:1), active control, single blinded, parallel two-arm, multi-center clinical investigation using Abbott Vascular ABSORB Everolimus Eluting Bioresorbable Vascular Scaffold System (ABSORB BVS); compared to…
- Trial name
- ABSORB II (NCT01425281)
- Testing
- Abbott Vascular XIENCE Everolimus Eluting Coronary Stent System, Abbott Vascular ABSORB Everolimus Eluting Bioresorbable Vascular Scaffold System
- Where
- Belgium
- Volunteers
- 501 people
- Sponsor
- Abbott Medical Devices
Acute Abdomen
The Commonest Medical, Surgical, and Oncological Causes of Acute Abdomen in Adults With COVID-19. A Prospective Observational Study.
Coronaviruses are a large family of viruses that can cause mild to severe respiratory infections. 2019-nCoV is a novel coronavirus that was discovered in Wuhan, China.
- Trial name
- NCT05295251
- Testing
- medical ,oncological and surgical treatment of cases of acute abdomen
- Where
- Egypt
- Volunteers
- 910 people
- Sponsor
- Zagazig University
Cardiovascular Disease, Diabetes
Meta-Analyses of Low-risk Lifestyle Behaviours and Patient Important Outcomes
Public health policy is universal in recommending the adoption of low risk low-risk lifestyle behaviors for health promotion and prevention of chronic or non-communicable diseases (NCDs).These behaviors generally include…
- Conditions
- Cardiovascular Disease, Diabetes, Cancer, Mortality
- Trial name
- NCT03234101
- Testing
- Low-risk lifestyle behaviours
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hemorrhagic Cystitis
Tolerability and Efficacy of INSTYLAN in Subjects With Moderate to Severe Hemorrhagic Cystitis
The purpose of this study is to assess the efficacy and tolerability of INSTYLAN (Sodium Hyaluronate 80mg/50ml) in Patients with early or late symptoms of moderate to severe hemorrhagic cystitis caused by pelvic radiation therapy…
- Trial name
- NCT04696666
- Testing
- INSTYLAN (Sodium Hyaluronate 80mg/50ml)
- Where
- 10 sites in France
- Volunteers
- 30 people
- Sponsor
- LIDDE Therapeutics
Drug Resistance, Carbapenem-Resistant Enterobacteriaceae Infection
Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae
The purpose of this study is to evaluate the treatment outcomes in patients with CRE infections.
- Conditions
- Drug Resistance, Carbapenem-Resistant Enterobacteriaceae Infection, Sepsis, Septic Shock
- Trial name
- NCT04516395
- Testing
- Combined antibiotic regimens, Standard antibiotic regimens
- Where
- Thailand
- Volunteers
- 102 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Clubfoot
Exploring the Causes of Clubfoot Using Magnetic Resonance Imaging, MRI
The purpose of this study is to: 1. compare structural variations observed in the calf and foot of the clubfoot mouse model(pma)with human clubfoot patients antenatally and postnatally; 2.
- Trial name
- NCT01088828
- Testing
- Magnetic Resonance Imaging (MRI) of calf and foot
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
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