Clinical trials: Executive Function Disorders
ADHD, Dyslexia
Computerized Working Memory Training
Prior research has found that children with attention-deficit hyperactivity disorder (ADHD) and reading difficulties (RD) are at an elevated risk of developing further cognitive deficits and developmental challenges.
- Trial name
- NCT06567444
- Testing
- Working memory intervention
- Where
- Hong Kong
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Primary Brain Tumor
Neurocognitive Function After Proton Therapy in Children and Adolescents
Brain tumors are the second most frequent malignant diseases in children and adolescents. In the study the short and medium term consequences of proton therapy on cognitive processes in particular on executive functions in…
- Trial name
- ELBE-ProKids (NCT04066465)
- Where
- 3 sites in Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Alzheimer Disease 2 Due to Apoe4 Isoform
Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD
This study explores the acute exercise effect on neurocognitive function and also its potential moderators in an exercise setting and Apolipoprotein E (APOE) genetic risk.
- Trial name
- NCT05591313
- Testing
- LI-40, MI-30, HI-16
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
HIV Infections
Perspective Memory and Executive Functions in HIV+ Patients
The primary goal of this observational study is to evaluate prospective memory in HIV+ patients compared to healthy subjects. The secondary goal is to examine the relationship between prospective memory and Hot Cognition…
- Trial name
- (3514) (NCT05752578)
- Testing
- Neuropsychological testing
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stuttering, Childhood, Executive Dysfunction
Executive Function Performance in Children Who Stutter
The study aims to asses the executive function in children who stutter for better management of those children
- Trial name
- NCT05640440
- Testing
- Executive function testing
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cardiovascular Diseases, Respiratory Diseases
Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children
This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age…
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Mental Health Disorders, Heat Illness
- Trial name
- NCT07643571
- Testing
- WeChat Mini-program Based Heat Health Risk Early Warning Intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Logopenic Progressive Aphasia, Primary Progressive Aphasia
Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA
AD afflicts over 5.5. million Americans and is one of the most expensive diseases worldwide. In AD the variant in which language functions are most affected are referred to as 'logopenic variant Primary Progressive Aphasia'…
- Trial name
- NCT03887481
- Testing
- High-definition active tDCS (HD-tDCS) + "Repeat After Me" (RAM) Treatment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Aging, Age Related Hearing Loss
Cognitive Training to Improve Mobility in Middle-aged and Older Adults
The proposed study is designed to evaluate the effect of at-home executive function training on cognition and mobility in older adults with age-related hearing loss (ARHL), older adults with normal hearing, and middle-aged adults.
- Trial name
- HnW (NCT05418998)
- Testing
- Executive function (EF) training
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
Self-regulation, Appetitive Behavior
Food for Thought: Executive Functioning Around Eating Among Children
Scientific knowledge of the cognitive-developmental processes that serve to support children's appetite self-regulation are surprisingly limited.
- Conditions
- Self-regulation, Appetitive Behavior, Eating Behavior, Child Obesity
- Trial name
- NCT06108128
- Testing
- Executive functioning observational tasks
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Temple University
Internet Addiction Disorder
Examining of Occupational Balance, Executive Functions, and Quality of Life of Adolescents with Internet Gaming Disorder
Internet gaming disorder leads to social problems and isolation, neglect of daily responsibilities, behavioral disorders, and cognitive and physical impairments.
- Trial name
- NCT06497166
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Attention Concentration Difficulty, Depression
Training Resiliency in Youth (TRY) Study
The aim of the study is to determine whether a neuroscience-inspired cognitive remediation video game (EVO) that targets the cognitive control network (CCN) will improve executive functioning (EF) and resilience to psychiatric…
- Conditions
- Attention Concentration Difficulty, Depression, Anxiety
- Trial name
- TRY (NCT03429465)
- Testing
- EVO Cognitive Remediation Game
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Washington
Breast Cancer
Assessment of Sensory Gating, Attention, and Executive Control in Breast Cancer
This study is being done to find out if a new series of evaluations called the SAE (Sensory-Attention-Executive) Battery can help researchers learn more about how cancer treatment does or does not change the way the brain…
- Trial name
- NCT03619083
- Testing
- SAE battery, Assessments
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Parkinson's Disease
The Effect of Rasagiline on Cognition in Parkinson's Disease
While Parkinson's disease has historically been defined in terms of its motor symptomatology, studies have shown that non-motor deficits form an important part of the syndrome.
- Trial name
- NCT01382342
- Testing
- Rasagiline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brown University
Obesity
The Effects of Interrupting Prolonged Sitting With Bouts of Physical Activity on Neurocognitive Function in Obesity
It is projected that by 2030 almost 50% of adults in the USA will have obesity. High sedentariness and physical inactivity contribute to the obesity pandemic. Neurocognitive deficits compound the global burden of obesity.
- Trial name
- SITLess (NCT04926207)
- Testing
- Physical Activity Breaks Intervention, Talking Breaks Control
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cognitive Change, Diet, Healthy
Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
- Trial name
- NCT06605898
- Testing
- MIND Diet, Control Diet
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Attention Deficit Hyperactivity Disorder
Neurocognitive Exercise Program for Children With Attention Deficit and Hyperactivity Disorder
The effects of Neurocognitive Exercise Program (NEP) on ADHD symptoms and executive functions in children with Attention Deficit and Hyperactivity Disorder (ADHD) will be investigated using The Conners parent rating scale-revised…
- Trial name
- NCT04707040
- Testing
- Neurocognitive Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Parkinsonism or Parkinson's Disease Nos
Self-Reports of Executive Functions in Persons With Parkinson's Disease and Their Significant Others
The investigators are conducting a study to compare the self-reports of executive functions (that is to say, what role cognitive processes such as working memory and attention) in persons with Parkinson's Disease to the reports…
- Trial name
- NCT04928027
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Attention Deficit Hyperactivity Disorder
Contribution of Attachment and Educational Practices in the Expression of ADHD in School-aged Children
ADHD is a neurodevelopmental disorder characterized by the presence of persistent signs of associated hyperactivity-impulsivity and/or inattention that impair the child's functioning or development.
- Trial name
- CASPI-ADHD (NCT04337125)
- Testing
- Neuropsychological and attachment/parenting assessment
- Where
- 2 sites in Belgium
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Queen Fabiola Children's University Hospital
Child Development, Under Nutrition
Impact of Graduation on Child Development in Uganda - Wave 2 (Ancillary/Extension)
This ancillary/extension study ("Wave 2") measures child development and school readiness outcomes among children residing in households within host communities that participated in the Graduation to Resilience (G2R) randomized…
- Conditions
- Child Development, Under Nutrition, School Readiness, Anemia
- Trial name
- NCT07212374
- Testing
- Graduation
- Where
- Uganda
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Attention Deficit Hyperactivity Disorder
Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices
A new company called CogCubed has created a new game based on the Sifteo Cube (http://www.sifteo.com) platform. These new hands-on digitized cubes are unique, motion-sensitive wireless blocks that contain multiple sensors that…
- Trial name
- NCT01711372
- Testing
- Groundskeeper game for controls, Groundskeeper game for ADHD
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- CogCubed, Corp