Clinical trials: Exercise Metabolism
Obesity
Resistance Exercise and Muscle Protein Synthesis in Obese Adults
Obesity has numerous comorbidities that are associated with exceedingly high healthcare costs. In addition to well- characterized impairments in lipid and glucose metabolism, obesity is associated with altered protein metabolism.
- Trial name
- NCT03411681
- Testing
- Resistance Exercise
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Obesity, Hypertension
Physical Activity, Functional Capacity and Quality of Life in Older Patients With Chronic Comorbidities
The prevalence of obesity, hypertension (HT) and type 2 diabetes (T2D) is increasing. The adoption of an increasingly sedentary lifestyle is one of the main factors contributing to the increased incidence of chronic diseases such…
- Conditions
- Obesity, Hypertension, Type 2 Diabetes
- Trial name
- NCT06535295
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Biruni University
Physical Activity
ILSI Energy Balance Study
The purpose of this study is to apply measurement error techniques on consumer devices to assess rate of energy storage [ES] and energy expenditure [EE], then estimate EI using the intake-balance technique.
- Trial name
- NCT04142281
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Sedentary Lifestyle, Metabolic Disturbance
Sedentary Behavior and Health Outcomes Study
This study is a randomized crossover trial to compare the effectiveness of interrupting SB on glucose homeostasis in the lab and free-living settings.
- Conditions
- Sedentary Lifestyle, Metabolic Disturbance, Pediatric Obesity, Physical Activity
- Trial name
- SBHO (NCT03153930)
- Testing
- Walking breaks, Sitting only
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Type 2 Diabetes Mellitus, Primary Prevention
The Impact of a Diabetes Risk Prediction Model in Primary Care.
Little evidence exists on the impact of diabetes risk scores, e.g. on physicians and patient's behavior, perceived risk of persons, shared-decision making and particularly on patient´s health.
- Trial name
- NCT03234322
- Testing
- external validated risk prediction model
- Where
- Germany
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Sarcopenia, Obesity
Citrulline Supplementation Combined With Exercise: Effect on Muscle Function in Elderly People (CITEX Study)
The main objective of this study is to determine if oral supplementation of Citrulline, when combined with HIIT, can produce significant changes in body composition, muscle quality, muscle metabolism and functional capacity in…
- Trial name
- CITEX (NCT02417428)
- Testing
- Citrulline, Exercise, without exercise
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Placebo, Tetraselmis Chuii
TetraSOD® Supplementation and Skeletal Muscle Redox Gene Expression
Tetraselmis chuii (TetraSOD) is a marine microalgae that has been reported to improve antioxidant responses in human skeletal muscle cells treated with TetraSOD and to improve recovery from muscle damaging exercise in humans…
- Trial name
- NCT06822556
- Testing
- Tetraselmis chuii
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Weight, Physical Activity
A Virtual Support Pilot Program for Weight Loss Surgery Patients
Obesity affects over one-third of the US population, and is associated with serious medical problems like diabetes and heart disease.
- Trial name
- NCT01770366
- Testing
- Weight and Exercise Lifestyle Support (WELS), Usual Care
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Osteoporosis
Effect of Two Exercise Programs on Bone Strength and Architecture
Bone responds according to the load placed on it. In this study, investigators want to know if exercise that loads the body in exercises, like walking or jogging (Ground Reaction Forces: GRF), affects bone differently than…
- Trial name
- NCT02636530
- Testing
- Ground Reaction Forces, Joint Reaction Forces
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type 2
Whole Body Vibration and Diabetes Type 2
Diabetes generates a great impact on society, as well as a concern for health professionals due to its high and increasing prevalence; there are more and more studies that demonstrate the effectiveness of vibration platforms and…
- Trial name
- WBV (NCT05968222)
- Testing
- Vibration exercise
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Type 2 Diabetes Risk Reduction in Young Adults
Holistic Lifestyle mHealth Intervention for Risk Reduction of Type 2 Diabetes Mellitus in Young Adults
The goal of this clinical trial (randomized controlled trial) is to examine the effectiveness of a holistic lifestyle mHealth intervention in reducing the risk of type 2 diabetes mellitus.
- Trial name
- NCT07604012
- Testing
- Holistic mHealth Intervention
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Osteoporosis, Obesity
Breastfeeding and Exercise for Healthy Infants and Postpartum Moms Too!
Approximately 8 million American women suffer from osteoporosis, and one out of every two women over the age of 50 will have an osteoporotic-related fracture in their lifetime (42).
- Conditions
- Osteoporosis, Obesity, Weight Loss
- Trial name
- BEHIP (NCT00966381)
- Testing
- Exercise and weight loss intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Pregnancy, Overweight and Obesity
Pregnancy Exercise Mode Effect on Childhood Obesity
The overall objective of this proposal is to conduct a longitudinal prospective study of overweight/obese (OW/OB) pregnant women and their offspring to determine which prenatal exercise mode will have the greatest impact on…
- Trial name
- NCT04805502
- Testing
- Exercise Modes
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Metabolic Syndrome
Exercise and Carotid Artery Function in Metabolic Syndrome
The purpose of this study is to determine 1) if young adults with metabolic syndrome display endothelial dysfunction of the internal carotid artery in a sex-specific fashion and 2) if this endothelial dysfunction can be acutely…
- Trial name
- NCT07430839
- Testing
- exercise, Diagnostics, Inhaled CO2-mixed air
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Cardiovascular Risk Factor, Metabolic Disease
Effects of Shockwave Therapy Versus Radiofrequency
The main objective of this study is to compare the effect of 6 sessions of shock wave therapy versus radiofrequency followed by a protocol of moderate aerobic exercise, in the reduction of adiposity and abdominal flaccidity, in…
- Conditions
- Cardiovascular Risk Factor, Metabolic Disease, Photoaging
- Trial name
- NCT04282057
- Testing
- Radiofrequency, Aerobic exercise, Shock wave therapy
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Overweight, Obese
UCSD Take Charge Study
The purpose of the Take Charge Study is to determine among overweight and obese men and women with type 2 diabetes whether 1) participating in a commercial weight loss program promotes great weight loss and weight loss…
- Conditions
- Overweight, Obese, Obesity, Diabetic
- Trial name
- NCT01345500
- Testing
- Higher Carbohydrate, Lower Fat Diet, Lower carbohydrate, Higher fat diet, Individualized Counseling
- Where
- 2 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Type 1 Diabetes, Cardiovascular Risk Factor
Determinants of Cardiovascular Disease Risk Factors Among Youth With Type 1 Diabetes
Type 1 diabetes mellitus (T1D) is the most common form of diabetes among children and youth, and it is increasing around the world, particularly among children under 5 years.
- Trial name
- CARDEA (NCT04304729)
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Homocystinuria
Effects of Exercise on Metabolic Parameters in Classical Homocystinuria
The aim of this research project is to compare the effect of an aerobic exercise session in two different populations. Sampling biological material and collecting health-related personal data entails minimal risks and burdens.
- Trial name
- NCT04021732
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Energy Metabolism
Lactate Profile and Fat Oxidation During Exercise
The goal of this clinical trial is to test whether changes in lactate kinetics during exercise (due to glycogen depletion or hyperthermia) alter the pattern of fat oxidation during a maximal incremental cycle ergometer test in…
- Trial name
- LacFat (NCT05703100)
- Testing
- Incremental exercise test, Incremental exercise test under hyperthermia, Incremental exercise test under glycogen depletion
- Where
- Spain
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Heart Failure With Normal Ejection Fraction
Abnormal Vascular, Metabolic, and Neural Function During Exercise in Heart Failure With Preserved Ejection Fraction
Heart failure with preserved ejection fraction (HFpEF) accounts for approximately half of the heart failure population in the United States.
- Trial name
- NCT03465072
- Testing
- Exercise training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
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