Clinical trials: Exogenous Obesity
Ketogenic Diet, Weight Loss
Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.
This project will be a three-group controlled 6-wk feeding study where all meals are prepared and provided to obese participants. All participants will be fed a 25% energy-restricted diet.
- Trial name
- STAK (NCT06449287)
- Testing
- Diet, Blood Draw, Ketone/Glucose Monitoring
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Metabolic Syndrome
Ketone Esters for Appetite, Cognition, and Cardiovascular Function in Individuals With Obesity and Insulin Resistance
The goal of this single-blind randomized placebo-controlled trial is to test the effects of an oral ketone supplement on appetite, cognition, metabolism, and cardiovascular function in individuals with obesity and insulin…
- Trial name
- NCT05651243
- Testing
- Ketone Ester Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern Mississippi
Appetite, Obesity
Exogenous Ketones and Appetite
People with obesity have different appetitive responses to stimuli compared to people without obesity. For example, people with obesity have a blunted postprandial ghrelin ('hunger' hormone) response, lower glucagon-like peptide…
- Conditions
- Appetite, Obesity, Ketones, Appetitive Behavior
- Trial name
- NCT06327464
- Testing
- Exogenous ketones
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Obesity
Incretin Effect in People With Impaired Fasting Glucose
Regulation of endogenous glucose production (EGP) and insulin secretion are major actions of glucagon-like peptide-1 (GLP-1). Determining whether alterations in GLP-1 may contribute to abnormal EGP and insulin secretion in people…
- Trial name
- 1651 (NCT00795275)
- Testing
- Sitagliptin Phosphate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Exogenous Obesity
Video Game Playing on Lunch-time Food Intake in Children
The purpose of this experiment is to investigate the effect of video game playing for 30 minutes on food intake and subjective appetite. The investigators hypothesize that video game playing will affect food intake in children.
- Trial name
- NCT01750151
- Testing
- Glucose Beverage, Video Game Playing, Control Beverage
- Where
- 2 sites in Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Obesity, Menopause
A Cohort Research of Genetic Susceptibility for Common Obesity in Women
Not many studies examined genetic determinants of obesity in women. As pre-menopausal and post-menopausal women appear to have different propensities for fat deposition, genetic loci linked with obesity-related phenotypes might…
- Trial name
- CROWN (NCT01488903)
- Where
- Taiwan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Child Obesity
More Outside Your Door: a Diet/physical Activity Intervention to Decrease Risk of Obesity in Alaska Native Preschoolers
The preschool age is a crucial period of growth and an optimal time to begin to establish healthy eating and physical activity habits leading to better food and activity choices into adulthood, thereby minimizing risk for…
- Trial name
- MOYD (NCT06303544)
- Testing
- Wedge 1
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Alaska Native Tribal Health Consortium
Simple Obesity
Nutritional Video Intervention Using Mindfulness-based Principles
The purpose of this study is to access the acceptability and potential utility of nutritional intervention videos in 1) changing knowledge and attitudes about healthy eating, 2) improving healthy food shopping practices, and 3)…
- Trial name
- NCT02494661
- Testing
- Healthy Cart and Stress Management Videos, Healthy Cart Video
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Exogenous Obesity
Sedentary Screen Time Activities on Food Intake
The purpose is to investigate the effect of sedentary screen time activities on food intake and subjective appetite in 9- to 14-year old normal weight and overweight/obese girls.
- Trial name
- NCT01750177
- Testing
- Television Viewing before mealtime, Video Game Playing, Computer Use
- Where
- 2 sites in Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Diabetes Mellitus, Obesity
Gymnema Sylvestre vs Berberine in Obesity Gene Expression of Adipokines
Obesity is a disease that affects a large part of the world's population and is a risk factor for the development of metabolic, cardiovascular, oncological, and neurodegenerative diseases.
- Trial name
- GS VS BBR A (NCT06426966)
- Testing
- Berberine, Gymnema sylvestre
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Polytechnic Institute, Mexico
Children, Exogenous Obesity
The Feeding Dynamic Intervention: Self Regulation of Intake in Preschoolers
In this study the investigators will examine the Feeding Dynamic Intervention (FDI) as a tool to prevent obesity in young children.
- Conditions
- Children, Exogenous Obesity, Eating Behavior
- Trial name
- FeeDIn (NCT01515254)
- Testing
- lifestyle counseling, parental feeding
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Obesity, Cardiovascular Disease
Role of Cardiometabolic Risk Factors in Childhood Bone Development
The proposed research brings together complementary expertise to systematically elucidate the longitudinal effects of (1) total and regional body fat and (2) the metabolic impairment that accompanies obesity on bone development…
- Conditions
- Obesity, Cardiovascular Disease, Type 2 Diabetes, Osteoporosis
- Trial name
- NCT02355717
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Augusta University
Obesity, Overweight
Gene Modulation of NLRP3, IL-1β and TNF-α in Peripheral Blood of Patients With Exogenous Obesity Treated With Berberine
The patients will be invited to participate in a research study aimed at determining the Gene Modulation of NLRP3, IL-1β and TNFα in peripheral blood of patients with exogenous obesity treated with berberine.
- Conditions
- Obesity, Overweight, Berberine
- Trial name
- Obesity-Berber (NCT06703086)
- Testing
- Berberine Hydrochloride group, nutritional plan, controlled moderate aerobic exercise
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Polytechnic Institute, Mexico
Obesity
Whole Body Vibration and External Load Exercise Training on Cardiovascular and Autonomic Function in Obese Individuals
Obesity is directly related to arterial dysfunction and negatively associated to muscle strength. High-intensity resistance exercise is the favored modality to offset muscle weakness, yet, adverse effects on arterial function…
- Trial name
- NCT02679898
- Testing
- Unloaded-Whole Body Vibration (WBVT), Loaded-Whole Body Vibration (WBVT)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Florida State University
Obesity, Childhood, Obesity, Adolescent
PROBESITY-2: Synbiotics in Pediatric Obesity
The global obesity epidemic presents an unprecedented challenge to the public health worldwide. The factors associated with obesity are complex, and include health behaviours, such as eating habits and daily physical activity…
- Trial name
- PROBESITY-2 (NCT05162209)
- Testing
- Synbiotic
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Weight Loss, Simple Obesity
A Clinical Trial of Thread-embedding Therapy at Acupuncture Point for Simple Obesity
Thread-embedding Therapy has been used for treating Obesity in recent years. This research is aimed to observe the clinical effect of thread-embedding therapy in treating Simple Obesity.
- Trial name
- NCT03325179
- Testing
- Thread-embedding Therapy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Simple Obesity
Research on Mechanism of Massage Therapy on Energy Metabolism Disorder of Simple Obesity
This project is to penetrate and consummate the research mechanism of massage therapy on simple obesity. Latest researches indicate that the energy regulation network system of hypothalamus and metabolic disorders on adipocyte…
- Trial name
- NCT02339480
- Testing
- Massage therapy
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Guiyang College of Traditional Chinese Medicine
Wound Dehiscence
External Negative Pressure Dressing System vs. Traditional Wound Dressing for Cesarean Section Incision in Obese Women.
Obesity is associated with increased cesarean section delivery rates and surgical site infections with associated increased post-operative morbidity, post-operative pain and length of hospital stay.
- Trial name
- NCT04434820
- Testing
- External negative pressure dressing system (Yuwell 7E-A portable suction unit)
- Where
- Egypt
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Fractures
Influence of External Factors on Skeletal Growth in Youth
Objective: Prospective study regulation in bone mass, size, architecture, cortical, trabecular bone, soft tissues and risk factors for cardiovascular disease at growth. Determine regulation by environmental factors.
- Trial name
- NCT00633828
- Testing
- Increased physical education in primary school (daily)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Region Skane
Fetal Developmental Abnormality, Fetal Development
Scottish Advanced Fetal Research Study
In-utero exposure to drugs and chemicals through maternal smoking, alcohol use, drug abuse, prescription medicines and occupational/lifestyle exposures is widespread.
- Conditions
- Fetal Developmental Abnormality, Fetal Development, Human, Life Style
- Trial name
- SAFeR (NCT04613583)
- Testing
- SAFeR fetuses
- Where
- United Kingdom
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen