Clinical trials: Experience
Adverse Childhood Experience, Endothelial Function (FMD)
Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity
Adverse childhood experiences (ACEs) represent highly stressful events in the first 18 years of life that include abuse, neglect, and household and community-level dysfunction.
- Conditions
- Adverse Childhood Experience, Endothelial Function (FMD), Endothelial Injury, Mitochondrial Function
- Trial name
- PROMISE (NCT07244809)
- Testing
- Mitoquinone mesylate (MitoQ)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Cognitive Health, mHealth Application
Cognitive Training RCT for Older Chinese Americans
The purpose of this study is to develop and pilot test a mHealth intervention for cognitive training that is culturally and linguistically relevant to older Chinese Americans
- Conditions
- Cognitive Health, mHealth Application, Experience-based Co-design, Cognitive Training
- Trial name
- NCT05355870
- Testing
- Cognitive Training Intervention
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Duke University
Maternal Breastfeeding Experience, Maternal Breastfeeding Comfort
Laid Back Breastfeeding Position on Breastfeeding Experience
The goal of this clinical trial is to evaluate the effect of laid back breast feeding position on breastfeeding experience among multiparous women.
- Trial name
- LBB/PBE (NCT07196202)
- Testing
- Laid-Back position training, Standard Postpartum Care
- Where
- 2 sites in Egypt
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Mental Health Outcomes, Adverse Childhood Experiences
School Violence Exposure as an Adverse Childhood Experience
This study hypothesize that school safety strategies may contribute to poor mental health and distress among various school populations and proposes the following research questions to be answered through this study: 1.
- Conditions
- Mental Health Outcomes, Adverse Childhood Experiences, Perceived School Safety, Educational Outcomes
- Trial name
- NCT06153316
- Testing
- School shooting incident
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Preschool Age Children, Preschool Education
The Building Resilience Program: Examining Self-Regulation, Behavior, and Resilience in Under-Resourced Preschoolers With ACEs
# Brief Summary The goal of this clinical trial is to learn if a occupational therapy-led trauma-informed care intervention can improve resilience, self-regulation, coping skills, and emotional health in preschoolers ages 2-4…
- Conditions
- Preschool Age Children, Preschool Education, Adverse Childhood Experience, Mental Health
- Trial name
- NCT07170605
- Testing
- Mental health, positive coping strategies promoting self-regulation and adaptive skills, Standard care/School Readiness Condition
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cleveland State University
Adverse Childhood Experiences
Implementation of Adverse Childhood Experiences (ACEs) Policy
Adverse Childhood Experiences (ACEs) are pervasive among children with 45% experiencing at least one ACE and 10% experiencing three or more, placing them at high risk for toxic stress and symptomatology.
- Trial name
- NCT04916587
- Testing
- Implementation Strategy of ACEs Screenings, Usual Care
- Where
- United States
- Volunteers
- 7,645 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Suicide Prevention, User Experience
User Evaluation of Zelfmoord1813.be and Its Related Websites
Monitoring the availability and accessibility of suicide prevention information in Flanders remains crucial. In 2022, 1,024 people died by suicide in Flanders, and approximately 10,000 individuals required emergency care…
- Trial name
- NCT07071922
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Mental Health Issue, Adverse Childhood Experience
Chinese Community Sample of Hierarchical Model of Psychopathology
By validating Hierarchy Model of psychopathology(HiTOP) in Chinese community samples, this study aims for illumating the problem of diagnostic heterogeneity and high comorbidity within existing psychiatric classification systems…
- Trial name
- NCT06105970
- Testing
- No intervention
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Perception Disturbance, Visual Suppression
Visual Surround Suppression and Perceptual Expectation Under Psilocybin
The prospective pilot study will address the critical need for more precise characterizations of the acute visual effects of the drug psilocybin by measuring the impact of acute psilocybin intoxication on a perceptual task known…
- Conditions
- Perception Disturbance, Visual Suppression, Psychedelic Experiences
- Trial name
- NCT04424225
- Testing
- Psilocybin, Niacin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Work-Related Stress, Coping Behaviour
Qualitative Exploration of a Mobile Stress Management Intervention for Mental Health Workers
The goal of this qualitative intervention study is to explore the experiences of mental healthcare workers using the STAPP@Work app to manage work-related stress.
- Conditions
- Work-Related Stress, Coping Behaviour, User Experience of Mobile Application
- Trial name
- NCT06991439
- Testing
- A self-monitoring mobile application for stress management at work
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Sevda Demirel
Healthy, Psychedelic Experiences
Consciousness, Psilocybin, and Well-Being
This study is being done to identify a dosing strategy that will allow IV psilocybin to be administered to sleeping participants without awakening them.
- Conditions
- Healthy, Psychedelic Experiences, Sleep
- Trial name
- CoPE Pilot (NCT05592379)
- Testing
- Psilocybin, Clonidine, Saline
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
ANXİETY, EFT
EFT and First Clinical Experience Anxiety for Nursing Student
It was planned as a randomized controlled study to determine the effect of Emotional Freedom Technique (EFT) on Nursing Students' Pre-First Clinical Experience Anxiety.
- Conditions
- ANXİETY, EFT, CLİNİCAL EXPERİENCE, NURSİNG STUDENT
- Trial name
- EFT (NCT06950450)
- Testing
- EMOTİONAL FREE TECHNIQUE
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Adverse Childhood Experiences
ACEs Referral From PED
Adverse childhood experiences (ACEs) are traumatic exposures that can cause many negative health impacts across life. ACEs are common in patients who seek out care in pediatric emergency departments (PEDs); this is an opportunity…
- Trial name
- NCT06574633
- Testing
- In-person therapy, Telehealth therapy
- Where
- 4 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Emory University
Caries Experience
Comparison of CAMBRA123 and AAPD (CAT) for Caries Risk in Egyptian Children
This study goal is to compare two indices in Egyptian children aged 3-6 years in caries detection and time needed for assessment which will contribute to variable data for pediatric oral health assessment locally and globally.
- Trial name
- NCT06932939
- Where
- Egypt
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Cairo University
Personal Experience of Substance-assisted Therapy Using Psilocybin, MDMA, and LSD
The Role of Personal Experience for the Therapeutic Attitude in the Context of Substance-assisted Therapy Training
The study investigates two groups of participants of the SÄPT therapist's training starting in October 2022. The overall objective is to investigate the risks and benefits of personal experience (PE) with substance-induced…
- Trial name
- TherPsySE (NCT05570708)
- Testing
- MDMA, LSD, psilocybin
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Felix Mueller
Labor Dystocia, Labor Complication
The Norwegian World Health Organisation Labour Care Guide Trial (NORWEL)
Appropriate and timely care during birth is critical to the survival and health of women and their babies. In 2020, the World Health Organization (WHO) presented the Labour Care Guide (LCG) as the new recommended tool for…
- Conditions
- Labor Dystocia, Labor Complication, Labor Onset and Length Abnormalities, Labor (Obstetrics)--Complications
- Trial name
- NORWEL (NCT05791630)
- Testing
- the labour care guide (LCG)
- Where
- 10 sites in Norway
- Volunteers
- 23,650 people, healthy volunteers welcome
- Sponsor
- Ostfold Hospital Trust
Orthodontic Patient Experience
Orthodontic Patient Experience of Intraoral Scans Versus Alginate Impressions
CONTEXT: Digital scanning systems are becoming more and more popular with the advent of the COVID-19 pandemic. The risks surrounding aerosol-generating procedures (AGP) has resulted in practitioners changing their normal practice…
- Trial name
- OPESI (NCT05194956)
- Testing
- Intraoral scan, Alginate impressions
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
Feasibility, Acceptability
A Digital Resilience Intervention for Emergency Medical Service Workers
Emergency medical service (EMS) workers (i.e., ambulance service providers) experience triple the risk for anxiety, depression, and posttraumatic stress disorder (PTSD) compared to the general U.S. population.
- Conditions
- Feasibility, Acceptability, Adoptability, Meaning Made
- Trial name
- NCT06861400
- Testing
- Self-Reflective Resilience-Recovery Activity Promotion Training
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Syracuse University
Caries Experience
Evaluation of Dental Caries Using Caries Assessment Spectrum and Treatment Need (CAST) Index, International Caries Detection and Assessment System (ICDAS) Index and World Health Organization (WHO) Index
This study goals is to compare the three indices in Egyptian children aged 4 to 6 years in caries detection and time needed for the assessments which will contribute to valuable data for pediatric oral health assessments both…
- Trial name
- CAST/ICDAS/WHO (NCT06858462)
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adverse Childhood Experiences, Domestic Violence
The Impact of an Adapted Version of the Strengthening Families Program on IPV Among Caregivers and ACEs Among Children
Adverse childhood experiences (ACEs) are unfortunately common and the known outcomes are concerning. However, very little is currently known about programs that may prevent ACEs among children, such as witnessing intimate partner…
- Trial name
- NCT05129501
- Testing
- Experimental
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln