Clinical trials: Exposure Occupational, open to volunteers
Body Temperature Changes, Heat Stress
Working in the Heat at Simulated Altitude: Effects of Normobaric Hypoxia on Physiological Strain
Extreme heat events are becoming more frequent, intense, and prolonged, increasing the risk of heat-related illness among workers performing physically demanding work in hot environments.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07664462
- Testing
- Simulated Occupational heat exposure under normoxic conditions, Simulated Occupational heat exposure under hypoxic conditions
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Ottawa
Occupational Exposure
Unloading Maneuvers During Spinal Flexion Exposure
An experimental study, which will aim to investigate the acute effects of unloading maneuvers during an intermittent spinal flexion protocol on changes in trunk mechanical and neuromuscular properties.
- Trial name
- NCT07116720
- Testing
- Unloading maneuvers
- Where
- Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Noise Exposure, Hearing Loss, Noise-Induced
A Multilevel Intervention to Prevent Noise Exposure in Farmworkers
This study will test a program to reduce noise exposure and prevent hearing loss among farmworkers. Farmworkers are often exposed to high levels of noise from machinery, which can lead to hearing loss over time.
- Conditions
- Noise Exposure, Hearing Loss, Noise-Induced, Occupational Exposure
- Trial name
- POP (NCT07554378)
- Testing
- Multilevel Hearing Protection Training
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Psychological Stress, Anxiety
NeuroFinance Human Stress Trial During Financial and Informational Volatility
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven…
- Conditions
- Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction
- Trial name
- NFHST (NCT07622589)
- Testing
- Wearable Physiologic Monitoring Platform
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Body Temperature Changes, Heat Stress
Progressive Heat Exposure and Physiological Strain
Occupational heat-stress guidelines are commonly based on the level of environmental heat exposure and are largely derived from studies conducted under constant environmental conditions.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07847437
- Testing
- Constant Heat Exposure, Progressively Increasing Heat Exposure
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Ergonomics, Occupational Injuries
Effect of the "EMS Back-Up" Ergonomic Program on Paramedics' Manual Handling Safety.
Effect of the "EMS Back-Up" Ergonomic Program on Paramedics' Manual Handling Safety.
- Conditions
- Ergonomics, Occupational Injuries, EMS Exposures or Injuries of EMS Personnel
- Trial name
- NCT07502131
- Testing
- EMS Back-Up Program
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Job Satisfaction, Bullying, Workplace
Mobbing Exposure and Job Satisfaction Among Physiotherapists
Physiotherapists, who hold a significant place in the healthcare sector, are at risk for mobbing and low levels of job satisfaction due to both demanding physical working conditions and emotional stress.
- Trial name
- NCT07402824
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Work-Related Musculoskeletal Disorders, Ergonomic Risk Exposure
Posture Protection Program for Musculoskeletal Disorders and Ergonomic Risk in Hospital Cleaning Staff
Cleaning work, particularly in hospital settings, is an occupation that demands high physical load on both the musculoskeletal and cardiovascular systems.
- Trial name
- POSKOP (NCT07590453)
- Testing
- Posture Protection Program
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Skin Melanoma, Cutaneous Melanoma
Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
The goal of this observational study is to learn about the link between work-related sun exposure and a specific type of skin cancer called melanoma in people living in the Modena area, Italy.
- Trial name
- Mesur (NCT07251335)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia
Lung Cancer
Lung Cancer Screening in a Population Exposed to Occupational Lung Carcinogens
The good clinical practice guidelines for the surveillance of workers after occupational exposure to lung carcinogens were approved by the Haute Autorité de la Santé (French National Authority for Health) and the Institut…
- Trial name
- LUCSO (NCT03562052)
- Where
- 8 sites in France
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Glioblastoma
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
The goal of this observational study is to find out what factors affect the health and risks in adults with glioblastoma (GBM), a grade 4 brain cancer.
- Trial name
- Key LARGO (NCT06625684)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Environmental Exposure, PFAS Exposure
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
This study is designed to evaluate the effect of a probiotic dietary supplement containing Streptococcus salivarius on serum PFAS levels in male firefighters with documented occupational PFAS exposure, following twice-daily use…
- Trial name
- AFCRO202 (NCT07846371)
- Testing
- Streptococcus salivarius 46-SL1
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cambiotics ApS
Interstitial Lung Diseases (ILD), Pulmonary Emphysema
Clinical Utility of LIBS Multi-Element Imaging and the IFF Algorithm in Chronic Lung Diseases
PNEUMO-LIBS is a multicenter, non-interventional observational study designed to evaluate whether multi-element tissue imaging by Laser-Induced Breakdown Spectroscopy (LIBS), combined with an artificial intelligence-based…
- Conditions
- Interstitial Lung Diseases (ILD), Pulmonary Emphysema, Chronic Lung Diseases, Occupational Lung Diseases
- Trial name
- PNEUMO-LIBS (NCT07597187)
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Grenoble
Exposure Occupational, Pulmonary Diseases
Use of Anti-CD146 Autoantibodies for the Diagnosis of Pulmonary Diseases Secondary to Occupational Exposure to Silica
This prospective, multicenter study aims to evaluate the relevance of anti-CD146 autoantibodies (AACD146) as biological markers for the early diagnosis of pulmonary diseases related to occupational exposure to silica.
- Trial name
- CD146-SILICE (NCT07376291)
- Testing
- Respiratory function testing, blood sampling, CT scan
- Volunteers
- 110 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Formaldehyde, Pathological Anatomy and Cytology
Experimentation of Formaldehyde Purification by Plants in the Anatomy and Cytology Department
Formaldehyde is notably used as a tissue fixator in pathological anatomy. Despite its toxicity, it continues to be widely used because it is currently not substitutable.
- Trial name
- DETOXANAPATH (NCT07264504)
- Testing
- Biological measurement of urinary formic acid, Plant installation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Noise Exposure, Noise-induced Hearing Loss
Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss
The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia devices for preservation of sensory structures in the cochlea after noise exposure. The main aims of the study are: 1.
- Conditions
- Noise Exposure, Noise-induced Hearing Loss, Noise; Adverse Effect, Mild Therapeutic Hypothermia
- Trial name
- NCT06729632
- Testing
- Cold pack-delivered mild therapeutic hypothermia
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Restorear Devices LLC
Cancer
Occupational Exposures Among Firefighters
This study aims to understand the effect of occupational exposures, including PFAS exposures, among firefighters.
- Trial name
- NCT06173843
- Testing
- PFAS / heavy metal testing, exposures
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Vincere Cancer Center
Microvascular Dysfunction, Endothelial Dysfunction
Nailfold Capillaroscopy and Endothelial Biomarkers in Healthcare Workers Exposed to Chronic Low-Dose Ionizing Radiation
Chronic occupational exposure to low-dose ionizing radiation may lead to subclinical endothelial dysfunction and early microvascular alterations in healthcare workers.
- Conditions
- Microvascular Dysfunction, Endothelial Dysfunction, Occupational Radiation Exposure
- Trial name
- NCT07363187
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Sharps Injuries, Needlestick Injuries
AI-Supported Gamified Training for Sharps Injury Prevention in Nurses
This study aims to evaluate the effect of a Health Belief Model (HBM)-based, artificial intelligence (AI)-supported gamified training program on nurses' knowledge and attitudes toward the prevention of sharps injuries.
- Conditions
- Sharps Injuries, Needlestick Injuries, Occupational Exposure
- Trial name
- NCT07562867
- Testing
- Experimental: Intervention Group, control group
- Volunteers
- 36 people
- Sponsor
- Baskent University