Clinical trials: Extraction, Tooth
Pain
Comparing Articaine and Mepivacaine Without Palatal Injection in Pain Assessment During Maxillary Teeth Extraction
This study compares the the efficacy of buccal infiltration of 4% Articaine and 2% Mepivacaine without any palatal injection during extraction of maxillary teeth.
- Trial name
- NCT03470532
- Testing
- buccal infiltration of 4% Articaine with Epinephrine, buccal infiltration of 2% Mepivacaine with Epinephrine
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Impacted Tooth
Impacted Tooth With Immediate Implant Placement
This is a prospective study, in which there are involved four clinical cases of surgical extraction of impacted maxillary canines followed by immediate implant placement and immediate screw-retained temporary crown using a…
- Trial name
- ImmediateIMP (NCT07456553)
- Testing
- Implantology
- Where
- Italy
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Site Preservation, Soft Tissue Healing
Site Preservation Was Performed Through an Open Healing Oral Restorative Membrane
In this study, an open healing oral restoration membrane was used for site preservation in the esthetic area after tooth extraction to maintain the space for tooth extraction and bone formation.
- Conditions
- Site Preservation, Soft Tissue Healing, Anterior Dental Aesthetic Area
- Trial name
- NCT07334067
- Testing
- site preservation surgery with open healing, site preservation surgery with close sutures
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Wound Heal
Porcine Membrane vs Bovine Wound Dressing in Human Tooth Extraction Sites
The purpose of this study is to compare porcine collagen membrane and bovine collagen wound dressing in human tooth extraction sites. The outcomes measured will be soft tissue thickness changes as well as bone density changes.
- Trial name
- NCT05802602
- Testing
- Porcine Collagen Membrane, Bovine Collagen Dressing
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Plaque, Dental
Plaque Removal Efficacy of Four Dentifrices Following a Single Brushing
The purpose of this study is to evaluate and compare plaque removal efficacy of four dentifrices following a single timed tooth brushing.
- Trial name
- NCT04794439
- Testing
- Dentifrices
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Dental Crowding, Alveolar Bone Loss
Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults
This study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces.
- Conditions
- Dental Crowding, Alveolar Bone Loss, Malocclusion
- Trial name
- NCT07716007
- Testing
- Fixed orthodontic appliance, Clear aligners
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Wound Healing After Tooth Extraction
Comparing Cross-Linked and Non-Cross-Linked Hyaluronic Acid for Early Healing After Tooth Extraction
This study compares early healing after a non-surgical tooth extraction in adults. Participants are assigned by chance to one of three groups: cross-linked hyaluronic acid placed in the extraction site using a gelatin sponge…
- Trial name
- NCT07898163
- Testing
- Cross-linked sodium hyaluronate 1%, Non-cross-linked low-molecular-weight hyaluronic acid, Gelatin sponge
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cyprus Health and Social Sciences University
Dry Socket
The Influence of Intra-alveolar Application of Honey on Healing Following Extraction
A prospective randomized parallel trial will be carried out on 100 patients who have extraction of single molar tooth. Teeth extractions will be done under local anesthesia.
- Trial name
- NCT02678104
- Testing
- Tooth extraction, Chlorhexidine mouth wash, Intra-alveolar application of Manuka Honey
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Hemodynamics, Pain
Hemodynamic Effects of Different Vasoconstrictors in Mandibular Exodontia
Title of Study: The Effect of Different Vasoconstrictive Agents on Hemodynamics Among Patients Undergoing Simple Mandibular Exodontia: A Triple-Blind Randomized Controlled Trial Location: King Abdulaziz University Dental Hospital…
- Conditions
- Hemodynamics, Pain, ASA I-II Requiring Simple Dental Extraction of a Mandibular Tooth
- Trial name
- NCT07013071
- Testing
- 2% Mepivacaine with 1:100,000 epinephrine, 2% Mepivacaine with 1:55,000 Epinephrine Bitartrate
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Tooth Abrasion
Enamel Abrasion and Stain Removal Efficacy of Two Whitening Toothpastes: An In-vitro and In-vivo Trial
The aim of the study is to clinically evaluate the efficacy of external stain removal of an activated charcoal based tooth paste versus calcium carbonate /perlite tooth paste.
- Trial name
- NCT05650840
- Testing
- Charcoal based whitening toothpaste (signal charcoal white& Detox toothpaste Unilever Mashreq - Egypt, Calcium carbonate /perlite containing whitening toothpaste (signal whitening moonlight toothpaste Unilever Mashreq - Egypt).
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain Perception of the New Device
Assessment of Maxillary Local Anesthesia Infiltration Using Needle-free Jet vs Conventional Syringe in Tooth Extraction
Managing pain and anxiety during dental anesthesia remains a key concern, particularly in procedures involving needle-sensitive adult patients.
- Trial name
- NCT07498621
- Testing
- needle-free anesthesia jet (Comfort-in™), Conventional dental syringe injection
- Where
- Saudi Arabia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Deep Caries, Pulp Exposure, Dental
Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions
Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions.
- Conditions
- Deep Caries, Pulp Exposure, Dental, Dental Caries
- Trial name
- NCT04052685
- Testing
- Selective removal to soft dentin (SRSD), Selective removal to firm dentine (SRFD)
- Where
- Turkey (Türkiye)
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- burcu gözetici
Dental Plaque, Oral Hygiene
Efficacy of Manual Toothbrushes in Removing Dental Plaque
This clinical methodology development study will evaluate the plaque removal efficacy of four marketed manual toothbrushes, with differing bristle types and brush head designs, in healthy dentate participants.
- Trial name
- NCT04025684
- Testing
- Oral B Indicator 123, Dr Best Original, Dr Best Multi Expert
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Immediate Dental Implant, Implant Osseointegration
Clinical and Radiographic Evaluation of Topical Vitamin D on Immediate Dental Implants
This study evaluates the clinical and radiographic outcomes of topical vitamin D application on immediate dental implants in patients undergoing single-rooted tooth extraction in the anterior mandibular region.
- Conditions
- Immediate Dental Implant, Implant Osseointegration, Vitamin D, Tooth Extraction
- Trial name
- NCT06806423
- Testing
- Immediate Dental Implant Placement without Adjunctive Treatments, Immediate Dental Implant Placement with Topical Vitamin D Gel Application
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Impacted Third Molar Tooth
Comparison of Two Flaps in Surgical Removal of Impacted Lower Third Molar
Project summary The surgical removal of mandibular third molar is one of the most common procedures done in oral and maxillofacial surgery.
- Trial name
- NCT05385679
- Testing
- Surgical Extraction of lower third molar
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ashutosh Kumar Singh
Tooth Loss
Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft
To compare dimensional changes in extraction socket of single rooted teeth, 6 months post extraction, when grafted with xenograft versus allograft.
- Trial name
- PilotXenAllo (NCT04550689)
- Testing
- Bone graft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- UConn Health