Clinical trials: Extremity
Upper Extremity Fracture
Effect of Infraclavicular and Interscalen Block on Oxygenitaon of the Forearm
to research the oxygenitaon effects of infraclavicular and interscalene blocks on the forearm.
- Trial name
- NCT04748211
- Testing
- Infraclavicular Block, Interscalen Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Becker Muscular Dystrophy, Limb-Girdle Muscular Dystrophy, Type 2A (Calpain-3 Deficiency)
Evaluation of Limb-Girdle Muscular Dystrophy
The purpose of this study is to understand the biochemistry of different types of Limb-Girdle Muscular Dystrophy (LGMD) and to determine appropriate outcome measures for future clinical treatment trials for LGMD.
- Conditions
- Becker Muscular Dystrophy, Limb-Girdle Muscular Dystrophy, Type 2A (Calpain-3 Deficiency), Limb-Girdle Muscular Dystrophy, Type 2B (Miyoshi Myopathy, Dysferlin Deficiency), Limb-Girdle Muscular Dystrophy, Type 2I (FKRP-deficiency)
- Trial name
- NCT00893334
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cooperative International Neuromuscular Research Group
Ankle Stability
Acute Effect of Standardized Ankle Taping on Lower Limb Asymmetry During Countermovement Jump in Healthy Judokas
This study aims to evaluate the acute effect of standardized taping of the dominant ankle on lower limb asymmetry during the countermovement jump (CMJ) test in healthy judokas.
- Trial name
- ASAT-CMJ (NCT07688330)
- Testing
- Standardized Ankle Taping, No ankle taping
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Triggerimpulse centar
Polydactyly Toe, Thumb Hypoplasia
Clonidine for Tourniquet-related Pain in Children
This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of…
- Conditions
- Polydactyly Toe, Thumb Hypoplasia, Trigger Finger, Polydactyly; Fingers
- Trial name
- CLOTCH (NCT04564430)
- Testing
- Catapresan, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Phantom Limb Pain
Incidence and Factors Affecting the Development and Outcome of Phantom Limb Pain (PLP) - A Single-centre Prospective Cohort Study.
Phantom limb pain (PLP), defined as pain felt in the missing portion of the amputated limb following amputation, occurs in a significant percentage of patients who undergo limb amputation and it is among the most difficult…
- Trial name
- NCT05005481
- Testing
- NIL intervention
- Where
- Singapore
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Multiple Sclerosis, Breath Tests
The Relationship Between Mechanical Properties of Respiratory and Lower Extremity Muscles and Other Parameters in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic inflammatory disease characterised by deterioration in the mechanics of the lower extremities and respiratory muscles and a decrease in respiratory function.
- Conditions
- Multiple Sclerosis, Breath Tests, MyotonPRO
- Trial name
- NCT07202780
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Sanko University
Chronic Low Back Pain
A Comparative Study: Non-Surgical Spinal Decompression and Spinal Manipulative Therapy- Utilizing a Quantifiable Musculoskeletal Functional Assessment Risk Analysis Tool (MSDR®) in Patients With Chronic Low Back Pain
To administer the MSDR® (Musculoskeletal Disorder Reporting) instrument to document the musculoskeletal profile of patients with chronic low back pain, a prospective, non-randomized, multicenter treatment trial
- Trial name
- NCT00732394
- Testing
- MSDR
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- MedAppraise, Inc.
Foot; Deformity, Valgus, Congenital, Foot; Deformity, Valgus (Acquired)
Effect of Medial Wedge on Static Balance in Pronated Feet
The use of heel wedges is often recommended as a clinical routine in individuals with foot pronation. However, there is a lack of information for examining the immediate effect of supports used to restore foot biomechanics on…
- Conditions
- Foot; Deformity, Valgus, Congenital, Foot; Deformity, Valgus (Acquired), Foot Deformities, Flatfoot
- Trial name
- NCT05437042
- Testing
- Medial calcaneal wedge
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Critical Limb Ischemia
A Safety and Tolerability Study of RJX Drug Product in Healthy Participants
Designed as a single center, two-part, double-blind, placebo-controlled, randomized study to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of RJX in healthy participants.
- Trial name
- NCT03680105
- Testing
- RJX
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Reven Pharmaceuticals, Inc.
Brachial Plexus Blockade
Nociception Level Index After Brachial Plexus Block In Upper Extremity Surgery
The present prospective within-subject observational study will evaluate whether unilateral brachial plexus block (BPB) induces measurable lateralized autonomic modulation, assesses using bilateral Nociception Level (NoL)…
- Trial name
- NCT07620002
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Hypotension
Dexamethasone Blunts the Hypotensive Effect of Spinal Anesthesia in Geriatric Patients Undergoing Lower Limb Orthopedic Surgeries
Based on the data that DEX increases the TPR and may decrease the expression of serotonin the investigator conducted this study to test the hypothesis that the prophylactic intravenous infusion (IVI) of DEX can attenuate the…
- Trial name
- NCT03664037
- Testing
- Dexamethasone phosphate
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
To Assess the Effectiveness of a Focal Vibration Treatment on Squat Power and Speed in Athletes Who Perform Squats
Focal Vibration for Enhancing Athletic Speed and Ppower
A focal vibration device will be used to perform an activation and warm-up protocol before performing a set of 7 repetitions of squat with 60% of your 1RM.
- Trial name
- NCT06671951
- Testing
- Focal Vibration
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Cerebral Palsy
Effect of Kinesio-taping of Lower Limbs
The goal of this clinical trail is to test if kinesio-taping on lower limbs has an effect on balance and gait in children with diplegic cerebral palsy.
- Trial name
- NCT06326164
- Testing
- kinesio-taping., A designed physiotherapy program.
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Lower Extremity Problem
Injury Prevention for Female Lacrosse Athletes
In this pilot study the investigators are testing whether an injury prevention program will help improve quality of movement and decrease number of injuries in collegiate women's lacrosse athletes.
- Trial name
- NCT06255899
- Testing
- Education Program on Injury Prevention, Individualized Feedback + Education Program on Injury Prevention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Older Adults
Effects of Home-based Lower Extremity Muscle Power Training on Functional Muscle and Balance Performance in Older Adults
Background: Muscle power, defined as the rate at which muscular force is generated to produce movement, declines more rapidly with age than muscle strength.
- Trial name
- NCT06901700
- Testing
- Experimental Group, control group
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Diabetic Foot, Lower Limb Wound
Diabetic Foot Care and Limb Preservation Pathway: Developmental Evaluation Study
University Health Network (UHN), working together with local primary care practitioners, patients, and community healthcare services is developing a Diabetic Foot Care and Limb Preservation Care pathway.
- Conditions
- Diabetic Foot, Lower Limb Wound, Diabetes, Amputation
- Trial name
- NCT05446337
- Testing
- Open-Ended Semi-Structured Interview
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Varicose Vein
Effect of Intensive Sports Practice on Lower Limb Varicose Veins
Compare the frequency of varicose veins in the lower limbs in a population exposed to intensive sport compared to individuals matched by sex, age and body mass index (BMI) did not have an intensive sport.
- Trial name
- VARISPORT (NCT02846051)
- Testing
- venous mapping
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Range of Motion
KinectROM Application for Assessing Range of Motion in Upper and Lower Extremity: A Development and Validation Study
The aim of the study is to investigate the validity and reliability of KinectROM application for objectively evaluating range of motion (ROM)
- Trial name
- KinectROM (NCT03731507)
- Testing
- Assessment of Range of Motion with Kinect Controller
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Saime Nilay Arman
Blood Pressure, Pulse Wave Analysis
Association of Synchronous Four-limb blOod pRessure and Pulse Wave velocIty With Cardiovascular Events
A multicenter prospective registry planned to recruit more than 100 000 patients 50 years old and older was carried out in China.
- Conditions
- Blood Pressure, Pulse Wave Analysis, Ankle Brachial Index, Patient Outcome Assessment
- Trial name
- ASORPWICE (NCT03521739)
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Obesity, Morbid, Metabolic Syndrome
Biometabolic Outcomes After Weight Loss Surgery: An Individualized Approach
Variable outcomes after weight loss surgery are likely attributable to complex, poorly understood mechanisms. Due to the significant impact that morbid obesity has on a patient's health, successful management of obesity and its…
- Conditions
- Obesity, Morbid, Metabolic Syndrome, NASH - Nonalcoholic Steatohepatitis
- Trial name
- NCT04841057
- Testing
- 50 cm BP limb length, 100 cm BP limb length, 150 cm BP limb length
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia