Clinical trials: Extremity
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Healthy Adolescents
Comparison of Upper and Lower Extremity Isometrics on Cognition in Healthy Adolescents
This study aims to compare the effects of upper and lower-extremity isometrics on cognition in healthy adolescents.
- Trial name
- NCT06047743
- Testing
- Alternating unilateral Isometric Handgrip Exercise, Dominant knee extension Isometric Exercise
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Amputation
Quantification of Motor Compensation Following Biomechanical, Proprioceptive and Physiological Alterations Post-lower Limb Amputation.
Lower limb amputation causes segmental loss that alters locomotor organization. The human body, designed to function in a multisegmental manner, must adapt to this new configuration where segments are missing, depending on the…
- Trial name
- QAMPA (NCT06780943)
- Testing
- Biomechanics, Physiological, Proprioceptive
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Unilateral Spastic Cerebral Palsy
"Be an Airplane Pilot": A Bimanual 3D Motion Analysis in Children With Unilateral Cerebral Palsy
Cerebral Palsy, in particular in its unilateral spastic form (uCP), is the main cause of motor disability in children, with a prevalence of 2/1000 births.
- Trial name
- BE-API (NCT03888443)
- Testing
- Bimanual 3D Motion Analysis " Be-API "
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Coordination and Balance Disturbances, Healthy
Effect of Lower Extremity Joint Manipulation on a Lower Extremity Somatosensory Illusion
The purpose of this study is to examine the influence of extremity manipulation on individual's center of pressure after they adapt to an ankle based illusion.
- Trial name
- NCT05226715
- Testing
- chiropractic manual therapy
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Parker University
Amputation
Detecting Change in Muscle Parameters, Pain, and Function With NMES for TTA
The proposal aims to investigate a non-invasive, cost-effective method for rebuilding muscle mass in individuals with transtibial limb loss.
- Trial name
- NCT06830876
- Testing
- Chattanooga Continuum Device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sara Peterson-Snyder
Healthy Volunteers
To studyJUV-161 Administered to Healthy Volunteers Undergoing Unilateral Lower Limb Immobilization (ULLI)
This is a double-blind, placebo-controlled, randomized study of 96 days total duration to assess the effect of JUV-161 on muscle disuse atrophy.
- Trial name
- NCT07397468
- Testing
- JUV-161
- Where
- 2 sites in New Zealand
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Juvena Therapeutics
Healthy Volunteers
Effects of tDCS on Anaerobic Power of Lower Limb Muscles
Anaerobic power and capacity are essential in many human activities, especially during sports practice that demand a high strength and power of the limbs.
- Trial name
- NCT04467476
- Testing
- Transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Piauí
Normal Weight Obesity, Metabolically Obese Normal Weight
Metabolic Obesity in Normal Weight (MONW): Diagnostic Markers Stud
Metabolically Obese Normal Weight (MONW) represents a phenotype affecting individuals with a normal Body Mass Index (BMI) but characterized by excessive adipose tissue accumulation.
- Conditions
- Normal Weight Obesity, Metabolically Obese Normal Weight, Metabolic Syndrome
- Trial name
- NCT07358533
- Where
- Poland
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Hyperthermia, Weather; Heat
Mitigating Heat-induced Physiological Strain and Discomfort in Older Adults Via Lower Limb Immersion and Neck Cooling
The incidence and severity of hot weather and extreme heat events (heat waves) is increasing. As such, there is an urgent need to develop heat-alleviation strategies that can provide targeted protection for older adults who are…
- Conditions
- Hyperthermia, Weather; Heat, Heat Stress, Heat Syncope
- Trial name
- NCT05601713
- Testing
- No cooling (control), Lower limb immersion, Lower limb immersion + neck cooling
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Physical Fitness
Task Oriented Basketball Training and Physical Fitness in Children
This study investigates the impact of task-oriented basketball training on physical fitness and upper extremity endurance in school children aged 9-12 in Lahore.
- Trial name
- NCT07729813
- Testing
- Medicine Ball Throw/Basket Ball, General Physical Activity
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Functional Deficits, Manipulation
Effects of Mobilization in Conjunction With Therapeutic Exercise in Participants With a History of Ankle Sprain
Our purpose was to examine the combined effects of thrust mobilization of the proximal and distal ankle joints in conjunction with a six-week rehabilitation program on ankle function in subjects reporting chronic ankle…
- Conditions
- Functional Deficits, Manipulation, Rehabilitation
- Trial name
- NCT02945943
- Testing
- High Velocity Low Amplitude mobilization, Exercise Protocol
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Shenandoah University
Sport Injury, Osteoarthritis, Knee
Biometric Recognition and Rehabilitation Assessment of Lower Extremity Sports Injury Based on Gait Touch Information
The current common clinical methods cannot truly reflect the biomechanical status of the knee joint. Based on the foot-knee coupling mechanism, the simple and practical dynamic gait touch information provided by the 3D force…
- Trial name
- NCT04462913
- Testing
- no intervention
- Where
- China
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Stroke, Movement, Abnormal
Effect of Virtual Reality Game on Upper Limb Movement in Individuals With Stroke
Individuals with stroke show abnormal movement pattern of upper limb. The movement pattern needs to be corrected. There are several methods to train normal movement.
- Trial name
- VRULS (NCT03277950)
- Testing
- Virtual reality with feedback, Virtual reality without feedback, Healthy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Vimonwan Hiengkaew
Neck Pain, Musculoskeletal Diseases
Effectiveness of Scapula Mobilization on Mechanosensitivity of Upper Limb Neural Test 1 in Mechanical Neck Pain
Between 45% and 70% of the general population suffers neck pain at some point in their lives, making it one of the most frequent reasons for taking sick leave.
- Trial name
- ULNT1 (NCT04168476)
- Testing
- Interscapular muscle release or scapular mobilization technique as described by Travell and Simons., Calcaneus abduction and adduction mobilization technique
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aitor Vaquero Garrido
Elbow
Rigid Taping for Increased Elbow Valgus
This study aims to investigate the acute effects of rigid taping based on the Mulligan Concept on elbow valgus angle, hand grip strength, and pinch strength in healthy young adults with an elbow valgus angle of 15 degrees or…
- Trial name
- NCT07864610
- Testing
- Rigid Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Gazi University
Adjuvants, Anesthesia, Subarachnoid Block
Intrathecal Nalbuphine Versus Intrathecal Tramadol in Subarachnoid Block for Lower Limb Orthopaedic Surgeries
This study compares the use of intrathecal nalbuphine versus intrathecal tramadol as adjuvant agents to local anaesthetics in subarachnoid block for lower-limb orthopaedic surgeries.
- Trial name
- NCT07294352
- Testing
- Intrathecal tramadol with spinal anesthsia, Intrathecal nalbuphine and spinal anesthesia
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Myofascial Trigger Point, Gastrocnemius Muscle
Effects of Myofascial Induction Pressure Pain Threshold in Trigger Points of the Proximal Muscles of Gastrocnemius
In the present study we will test the effects of myofascial induction technique in the muscles close to the application in the gastrocnemius muscle.
- Conditions
- Myofascial Trigger Point, Gastrocnemius Muscle, Manual Therapy, Pain Threshold
- Trial name
- NCT06499493
- Testing
- Myofascial induction in gastrocnemius muscle
- Where
- Spain
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mayuben Private Clinic
Amputation Wound, Traumatic Amputation of Toe
Longitudinal Study of Weight Change Following Lower Limb Amputation
The purpose of this study is to assess weight change in a population of Veterans with amputations. Little is known about the how weight changes following an amputation.
- Conditions
- Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
- Trial name
- NCT00932399
- Where
- United States
- Volunteers
- 4,549 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Ankle Sprains, Patellofemoral Pain Syndrome
Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders
Lateral ankle sprain (LAS) and patellofemoral pain syndrome (PFPS) are common musculoskeletal conditions associated with postural instability.
- Trial name
- LAS-PFPS (NCT07508163)
- Testing
- diagnosis of APSI, MLSI, OASI
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University