Clinical trials: Eye Disorders
Injury Brain, Eye Abnormalities
Reading Problems Associated With Central Nervous System (CNS) Pathologies.
This project aims to analyse eye movements, their alterations and influence in reading performance in patients with acquired CNS diseases and compare them with people of the same age, without neurological or ocular pathology and…
- Conditions
- Injury Brain, Eye Abnormalities, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT04937725
- Testing
- eye tracking
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Glaucoma
Analysis of the Eye in Patients With Primary Open-Angle Glaucoma and a Visual Field Defect in One Eye
The study aims to further understand glaucoma pathogenesis and progression by utilizing enhanced depth imaging optical coherence tomography to visualize and measure lamina cribrosa in vivo and segmentation technology to…
- Trial name
- NCT02622191
- Testing
- Spectral domain Optical Coherence Tomography
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Dry Eyes
Ocular Surface Dry Eye Microbiome
The investigators seek to characterize the identity of all microorganisms residing on the eye's surface (conjunctiva) in healthy eyes and those with dry eye syndrome, using a combination of analyses.
- Trial name
- NCT02306668
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pterygium of the Conjunctiva and Cornea
Randomized Controlled Trial of Subconjunctival Bevacizumab Injection in Impending Recurrent Pterygium
Hypothesis: Subconjunctival bevacizumab injection may potentially suppress neovascularization in pterygium, preventing or retarding the progression of recurrence.
- Trial name
- NCT01288404
- Testing
- Fluorometholone, Bevacizumab
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Pinhole
Functional and Physiological Changes Induced by Pinhole Glasses in Presbyopia
This study is aimed at presbyopic patients that do not require magnifying glass at close rage. The purpose of this study is to investigate the functional and physiological changes in eye induced by pinhole glass.
- Trial name
- NCT02722291
- Testing
- Trayner Pinhole Glasses (Trayner Glasses, Ivybridge Devon, U.K.)
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chung-Ang University Hospital
Pseudotumor Cerebri
Optic Nerve Sheath Diameters in Idiopathic Intracranial Hypertension Patients
Idiopathic intracranial hypertensionis a type of increased intracranial pressure. Diagnosis is made by lumbar puncture, which is an invasive technique.
- Trial name
- NCT04603118
- Testing
- Optic ultrasonography, Lumbar puncture
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Ege University
Central Serous Chorioretinopathy
Mindfulness for Central Serous Chorioretinopathy
The primary goal of this clinical trial is to test whether a mindfulness-based treatment is effective at shortening the duration of, and improving the features of, central serous chorioretinopathy in adults.
- Trial name
- MIND'S EYE (NCT07767058)
- Testing
- Mindfulness
- Where
- 6 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Multiple Sclerosis
Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis
The investigators principal hypothesis is that INO and optic neuritis are objective, quantitative, and reproducible models for corroborating the hypothesis that changes in core body temperature are associated with the reversible…
- Trial name
- NCT00854750
- Testing
- ACTHAR
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Elliot Frohman
Diplopia, Monocular
VisionApp - Ghosting
Recent Android mobile device technology is available which allows user-measured refractive error and reading add power. This technology could be quite useful to the clinical and research community.
- Trial name
- NCT07571538
- Testing
- Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Indiana University
Keratoconus
A Novel Method to Assess the Cornea Biomechanical Properties With Schiotz Tonometer
This study aims to use Schiotz tonometer to evaluate the corneal biomechanical properties. The administration of Schiotz tonometer is according to the routine protocol which is use to measure intra-ocular pressure.
- Trial name
- NCT02475343
- Testing
- Schiotz tonometer, UVA/riboflavin, femto-LASIK
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Zhiwei Li
Anesthesia, Intraocular Pressure
Establishment of an Anaesthetic Protocol for Examinations for Children With Glaucoma or Suspected Glaucoma
Correct measurement of the intraocular pressure of children with glaucoma or suspected glaucoma is essential for diagnosis and therapy.
- Conditions
- Anesthesia, Intraocular Pressure, Glaucoma, Suspect, Pediatric Glaucoma
- Trial name
- eyeBIS (NCT03972852)
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Myopia, Hyperopia
Safety and Efficacy Study of Topography-Guided LASIK to Treat Myopia and Hyperopia
This purpose of this study is to evaluate the safety and effectiveness of a topography-based custom ablation treatment using the ALLEGRETTO WAVE® Eye-Q 400 Hz laser system for treating myopia and hyperopia.
- Trial name
- NCT01028378
- Testing
- T-CAT topography-guided LASIK treatment with the Allegretto Wave Eye-Q 400 Hz Excimer Laser
- Where
- 10 sites in United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Clinical Research Consultants, Inc.
Hearing Impairment
Do Bluetooth Noise Cancelling Headphones Improve the Quality of Care in Hearing Impaired Patients?
Participants will be recruited by performing chart reviews of patients to be seen at University of Texas Medical Branch at Galveston Ophthalmology and Optometry Clinic. A sample size of at least 30 patients is needed (60 eyes).
- Trial name
- NCT05420038
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cataract, Refractive Errors
Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery
The two main objectives of this study are to demonstrate safety and effectiveness of implanting the PanOptix Trifocal IOL in patients who have had previous myopic Lasik.
- Trial name
- NCT04698278
- Testing
- PanOptix Trifocal Intraocular Lens
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Parkhurst NuVision Clinical Research LLC
Pupillary Dilation Effect During Cycloplegic Refraction
Comparing Efficacy and Safety of CTO0303 in Pediatric Subjects
This is a prospective randomized study compared with active control arm.
- Trial name
- NCT06609525
- Testing
- CTO0303-A, CTO0303-B, CTO0303-C
- Where
- South Korea
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Taejoon Pharmaceutical Co., Ltd.
Vitreomacular Adhesion
Prevalence of Vitreomacular Adhesion in Patients 40 Years and Older
The purpose of this study is to evaluate the prevalence of vitreomacular adhesion (VMA) in patients 40 years and older using Spectral Domain Optical Coherence Tomography.
- Trial name
- VAST (NCT02160340)
- Where
- 18 sites in United States
- Volunteers
- 1,584 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Eye Infections, Bacterial
Azithromycin Level in Tears and in Conjunctiva in 36 Healthy Volunteers
To evaluate azithromycin ocular conjunctiva concentrations 7 and 14 days after treatment initiation. To assess ocular and systemic tolerance/safety and azithromycin tear concentrations on Day 7
- Trial name
- NCT00356772
- Testing
- Azithromycin
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratoires Thea
Blepharoptosis, Ecchymosis; Eyelid
Fibrin Sealant in Eyelid Surgery
This study is looking at the effect of Tisseel in eyelid surgery. Fibrin sealants (Tisseel) cause there to be less bleeding during surgery. Surgeons have used Tisseel for over two decades to reduce bruising.
- Trial name
- NCT05358977
- Testing
- Tisseel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Presbyopia
The Light Sword Lens for Presbyopia Compensation
Clinical assessment of a new optical element for presbyopia compensation - the Light Sword Lens.
- Trial name
- NCT03716271
- Testing
- Visual Acuity Examination with a novel lens
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute
Diabetes (DM)
Feasibility Trial of a Sub-conjunctival Insert
The purpose of this single-centre, open label prospective study is to investigate a novel ocular mini insert (OMI) for detection of blood glucose levels in human subjects.
- Trial name
- OMI (NCT07105332)
- Testing
- OMI and Photometer
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- EyeSense GmbH
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