Clinical trials: Eye Disorders
Eye Cancer
Social-Psychological Aspects of Orbital Exenteration
The goal of this research study is to learn about the social and emotional factors that may affect the quality of life of patients with cancer of the eye or eye area who have had their facial appearance changed due to an orbital…
- Trial name
- NCT00601744
- Testing
- Audio-Taped Interview, Questionnaire
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Rheumatoid Arthritis, Systemic Lupus Erythematosus
A Trial in Healthy Adult Participants and Adults With Autoimmune Disease to Test How HBM7020 is Tolerated and Absorbed in the Body
This first-in-human study evaluates the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of HBM7020.
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Systemic Sclerosis, Sjögren's Disease
- Trial name
- NCT07649265
- Testing
- HBM7020
- Where
- Australia
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Allergic Conjunctivitis
A Study of MDI-1228_mesylate Ophthalmic Solution in Healthy Adults
The main goal of this clinical trial is to evaluate the safety, tolerability and pharmacokinetics (PK) profiles* of MDI-1228_mesylate Ophthalmic Solution in healthy adult participants.
- Trial name
- NCT05969236
- Testing
- MDI-1228_mesylate Ophthalmic Solution
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Medinno Pharmaceutical Technology Co., Ltd.
Age-related Macular Degeneration (AMD), Central Retinal Vein Occlusion (CRVO)
Evaluation of Physician Knowledge of Safety and Safe Use Information for Aflibercept in Canada
The primary objective of this study is to measure physician knowledge and understanding of the key safety information contained in the Eylea vial preparation instruction card, the intravitreal injection procedure video, and the…
- Conditions
- Age-related Macular Degeneration (AMD), Central Retinal Vein Occlusion (CRVO), Diabetic Macular Edema (DME)
- Trial name
- NCT02585401
- Testing
- Eylea (Aflibercept, VEGF Trap-Eye, BAY86-5321)
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bayer
Normal Healthy Subjects With No Known Ocular Diseases, Glaucomatous Eyes
Clinical Study of the Optic Disc Parameters
Assess the repeatability and agreement of the Optic Disc Parameters, Retinal Nerve Fiber Layer (RNFL) Thickness, and Full Retinal Thickness between the Maestro and iVue OCT devices
- Conditions
- Normal Healthy Subjects With No Known Ocular Diseases, Glaucomatous Eyes, Eyes With Retinal Diseases
- Trial name
- NCT02277119
- Testing
- Maestro, iVue
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Topcon Medical Systems, Inc.
Eye Diseases, Severe Loss of Vision
Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases
Rare Eye Diseases (RED) are the leading cause of severe visual impairment/ blindness (SVI/B) in children in Europe. This sensory disability with its accompanying psychological distress hugely impacts their lives and their…
- Conditions
- Eye Diseases, Severe Loss of Vision, Blindness, Quality of Life
- Trial name
- SeeMyLife (NCT06070467)
- Testing
- Mixed Methods Research (MMR) using quantitative (QUAN) and qualitative (QUAL) tools
- Where
- France
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Dry Eye Syndrome, Diabetes Mellitus Type 2
Comparison of Ocular Surface Features in Patients With Diabetes and Dry Eye Syndrome
The study aims to compare the differences of ocular surface features in controls and patients with diabetes and dry eye syndrome, to thoroughly evaluate the ocular surface health of diabetics, and to find out the relationship…
- Trial name
- NCT03576300
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Presbyopia
Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IOLs
Primary objective of this study is to introduce a modified luminous efficiency function that addresses the distinct total eye light transmittance of patients who underwent pseudophakic presbyopic correction with extended-depth of…
- Trial name
- V(λ)'_EDOF (NCT07077967)
- Testing
- Phacoemulsification with EDOF IOLs
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Presbyopia
Mix and Match Study of Two Multifocal Intraocular Lens With Different Add Power
To assess postsurgical visual acuity (distant, intermediate, near), refractive errors, contrast sensitivity, visual function and patient satisfaction after implantation of multifocal IOLs of different add power contralaterally.
- Trial name
- NCT02556944
- Testing
- Phacoemulsification with multifocal intraocular lens
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- tae-young chung
Infectious Disease, Neoplasms
AnovaOS Network Powered Patient Registry
The objective of this study is the development, implementation and management of a registry of patient data that captures clinically meaningful, real-world, data on the diagnosis, nature, course of infection, treatment(s) and…
- Conditions
- Infectious Disease, Neoplasms, Diseases of the Blood and Blood-Forming Organs and Certain Disorders Involving the Immune Mechanism (D50-D89), Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- Trial name
- NCT05013944
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Anova Enterprises, Inc
Eye Health, Age-related Macular Degeneration
Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults
Aging epidemics in Singapore are rapidly increasing and Age-related macular degeneration (AMD) prevalence is significantly associated with older age.
- Trial name
- NCT05064865
- Testing
- Freeze-dried table grape powder
- Where
- Singapore
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Noninfectious Uveitis
The Microbiome in Uveitis and Pediatric Inflammatory Diseases
Chronic, noninfectious uveitis in children, associated with various systemic inflammatory diseases, carries a high risk of vision loss.
- Trial name
- MUMIP (NCT07885501)
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Optic Neuritis
Pupillometry Dynamic Measures in Patients Without Ocular or Neurological Disease
Retrobulbar optic neuritis (NORB) is the damage to the optic nerve caused by inflammation. It causes a rapidly progressive and painful visual loss, often among young subjects.
- Trial name
- PCT (NCT02894281)
- Testing
- pupillary light reflex
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Dry Eye Syndrome
Efficacy Comparative Study Between Tears Again®, Opticol® and Optive®
Primary Purpose: To compare the efficacy in treating dry eye syndrome in contact lens wearers or computer users of Tears Again® versus Opticol® versus Optive® Secondary Purpose: Subjective evaluation of symptomatology Evaluation…
- Trial name
- NCT00893243
- Where
- Portugal
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital de Sao Sebastiao
Cataract
Efficacy of the AkkoLens IOL in Patients With Cataract
The goal of this observational study is to learn about the verification of the effectiveness and visual acuity of LUMINA in patients after lens replacement due to cataracts.
- Trial name
- NCT06231784
- Testing
- LUMINA IOL
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Vissum, Instituto Oftalmológico de Alicante
Presbyopia
Productivity Study of Presbyopia Improvement in Textile Workers
To establish, using a randomized, controlled design, the impact of near vision correction on the productivity of presbyopic textile workers in China, as measured by the change of monthly income.
- Trial name
- NCT04172935
- Testing
- Presbyopic Glasses/ Intervention Group
- Where
- China
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Corneal Endothelial Cell Loss, Secondary Intraocular Lens
Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes
This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).
- Trial name
- NCT04072978
- Testing
- Intraocular lens implantation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Glaucoma
Intraocular Pressure (IOP) Changes Associated With Muslim Prayer Postural Changes
Elevated intraocular pressure is widely accepted as a risk factor for glaucoma and controlling the pressure remains the cornerstone of effective treatment.
- Trial name
- NCT00454025
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Medication Adherence, Glaucoma
A Universal Eye Drop Adherence Monitor to Measure and Improve Adherence to Ocular Medications
Glaucoma is the second leading cause of visual impairment worldwide. Eye drop medications reduce vision loss from glaucoma by at least 60%, but eye drops must be taken every day to be effective.
- Trial name
- NCT03506568
- Testing
- Devers Drop Device (D3) app
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universal Adherence LLC
Cataract, Lens Opacities
Clinical Outcomes of MICROPURE and PodEye Monofocal Intraocular Lenses
Prospective, non-randomised, open, controlled, single-center post-market clinical follow study about Micropure 1.2.3. and PODEYE intraocular lenses.
- Trial name
- PHY1803 (NCT03796624)
- Testing
- Micropure 1.2.3., PODEYE
- Where
- Czechia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.