Clinical trials: FMT
Fecal Microbiota Transplantation
Profiling Fecal Samples for Selection of Donors of Feces
Fecal microbiota transplantation (FMT) represents a promising therapeutic in numerous clinical situations associated with dysbiosis.
- Trial name
- PROFIT (NCT04078581)
- Testing
- Questionnaire and fecal sample collection
- Volunteers
- healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hepatic Encephalopathy, Fecal Microbiota Transplantation
Fecal Microbiota Transplantation for the Treatment of Refractory Hepatic Encephalopathy After TIPS Surgery
This is a single-center, prospective, open-label, parallel-group exploratory clinical study designed to evaluate the safety and preliminary efficacy of fecal microbiota transplantation combined with standard medical therapy in…
- Conditions
- Hepatic Encephalopathy, Fecal Microbiota Transplantation, TIPS, Refractory Hepatic Encephalopathy
- Trial name
- NCT07683936
- Testing
- Fecal Microbiota Transplantation, Rifaximin、Lactulose, Dietary Fiber Prebiotic
- Where
- China
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
IBS - Irritable Bowel Syndrome, Microbial Substitution
The Optimal Route of Fecal Microbiota Transplantation for Irritable Bowel Syndrome
The object of this study is to find out is there an optimal route for the fecal microbiata transplant (FMT) in patients that suffer from irritable bowel syndrome.
- Trial name
- NCT05874830
- Testing
- Fecal microbiota transplant or plasebo through endoscopy
- Where
- 3 sites in Finland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Hepatic Encephalopathy
Microbiota, Sarcopenia, and Hepatic Encephalopathy Change in Cirrhotic Patients Before and After Rehabilitation
Through this plan, it will provide many benefits to patients with liver cirrhosis complicated with sarcopenia and/or hepatic encephalopathy, their family members, and the government in Taiwan: 1.
- Trial name
- NCT06040814
- Testing
- Rehabilitation Training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Constipation - Functional, Depressive Symptoms
FMT Treating Constipation Patients With Depression and/or Anxiety Symptoms - Clinical Efficacy and Potential Mechanisms
Constipated patients often have mental problems such as depression and anxiety due to difficult defecation. Our previous studies have proved the efficacy of FMT treating constipation.
- Conditions
- Constipation - Functional, Depressive Symptoms, Anxiety Symptoms, Gut-Brain Disorders
- Trial name
- NCT03233100
- Testing
- FMT
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jianfeng Gong
Inflammatory Bowel Diseases (IBD), Crohn's Disease (CD)
Fecal Microbiota Transplantation in Pediatric Patients
A disturbance in the diversity of gut bacterial composition could be linked to several immune mediated diseases including inflammatory bowel diseases (IBD).
- Conditions
- Inflammatory Bowel Diseases (IBD), Crohn's Disease (CD), Ulcerative Colitis (UC)
- Trial name
- FMT (NCT02108821)
- Testing
- Fecal Microbiota Transplantation (FMT)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Antibiotic Treatment
Restoration of Antibiotics Related Infant Microbiota Perturbations by Autologous Fecal Transplant
Antibiotics are lifesaving therapeutic drugs which have been used by adults, children, and infants alike for decades. There is an increase in global use of antibiotics over the course of lifetime and earlier in lifetime, with…
- Trial name
- aFMT-babies (NCT06609980)
- Testing
- autologous fecal matter transplant
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Enterobacteriaceae Infections, Fecal Microbiota Transplantation
Pilot Study Using Oral Capsule FMT to Decolonize GI CRE
Carbapenem-Resistant Enterobacteriaceae (CRE) are bacteria that have become resistant to carbapenems by producing enzymes that break down carbapenems.
- Trial name
- NCT03527056
- Testing
- Fecal Microbiota Transplantation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Healthy, Chronic Kidney Diseases
Innovative Approach to Fecal Microbiota Transplantation (FMT) Applied for Chronic Kidney Disease (CKD)
The aim of this PhD project focuses on the relationship between intestinal microbiota and health in the background of Chronic Kidney Disease (CKD).
- Trial name
- NCT04222153
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Antibiotic Resistant Strain
A Trial of Encapsulated Fecal Microbiota for Vancomycin Resistant Enterococcus Decolonization
The objective of this study is to provide preliminary insight into the safety and efficacy of fecal microbiota transplantation (FMT) for the eradication of gastrointestinal carriage of vancomycin-resistant Enterococcus.
- Trial name
- NCT03063437
- Testing
- Encapsulated fecal microbiota preparation
- Where
- 2 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Microbiome Health Research Institute
Fecal Microbiota Transplantation
Fecal Microbiota Transplantation in the Treatment of Inflammatory Bowel Disease
Fecal microbiota transplantation (FMT), defined as infusion of feces from healthy donors to affected subjects, is a method to restore a balanced gut microbiota and has attracted great interest in recent years due to its efficacy…
- Trial name
- FMT-IBD (NCT04436874)
- Testing
- endoscopy
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Crohn's Disease
Impact of the Fecal Flora Transplantation on Crohn's Disease
Crohn's disease is a chronic and relapsing inflammatory bowel disease. Many data show that the intestinal flora is involved in the disease and it has been show that patients with Crohn's disease exhibit an abnormal fecal flora…
- Trial name
- IMPACT-Crohn (NCT02097797)
- Testing
- Fecal Transplantation
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gastro-Intestinal Disorder
Healthy Stool Volunteer Donors for Fecal Microbiota Transplantation Trials
Currently, ANSM recommendations govern FMT (Fecal Microbiota Transplantation) in clinical trials. The collection and validation of these stool donations as part of the trials is complex and not very efficient.
- Trial name
- VIOLONSEL (NCT06478823)
- Testing
- Stools donation
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Attention-deficit/Hyperactivity Disorder
Washed Microbiota Transplantation for Attention-deficit/Hyperactivity Disorder
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by inattention and hyperactivity-impulsivity.
- Trial name
- WMT for ADHD (NCT06376331)
- Testing
- washed microbiota transplantation
- Where
- 2 sites in China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Clostridium Difficile
Fecal Transplant for Relapsing C. Difficile Infection
There has been an alarming increase in the incidence and severity of Clostridium difficile infection (CDI) in North America over the past decade.
- Trial name
- NCT01703494
- Testing
- Fecal Microbiota Transplantation
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Colleen Kelly
Ulcerative Colitis, Irritable Bowel Syndrome
Fecal Microbiota Transplantation for Health Improvement (TFM3)
Search for mechanisms of the effect of fecal transplantation on a healthy organism and various nosological forms.
- Conditions
- Ulcerative Colitis, Irritable Bowel Syndrome, Crohn Disease, Irritable Bowel
- Trial name
- TFM3 (NCT04011943)
- Testing
- Fecal Microbiota Transplantation
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federal Research and Clinical Center of Physical-Chemical Medicine
Biliary Atresia
Gut Microbiome in Biliary Atresia
The investigator will investigate the gut-microbiome and liver elasticity of the Biliary Atresia (BA)-patients before and after Kasai operation.
- Trial name
- NCT04260503
- Testing
- Monitoring of the gut-microbiome and ultrasound elasticity., Monitoring of the gut-microbiome, Monitoring of the gut-microbiome.
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Morbid Obesity, Metabolic Syndrome
FMT in Obesity: RYGB vs. LEAN vs. Autologous FMT
This double-blinded proof-of-concept study is proposed to explore the effects of fecal microbiota transfer (FMT) in human subjects.
- Conditions
- Morbid Obesity, Metabolic Syndrome, Diabetes, PreDiabetes
- Trial name
- DACH (NCT06268990)
- Testing
- Fecal microbiota transplantation
- Where
- Austria
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Wiebke Kristin Fenske
Obesity; Familial
Assessment of the Health Improvement of Obese Patients After Fecal Microbiota Transplantation (FMT)
Search for mechanisms of the effect of fecal microbiota transplantation on patients with obesity
- Trial name
- NCT04579263
- Testing
- Fecal microbiota
- Where
- 2 sites in Russia
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Federal Research and Clinical Center of Physical-Chemical Medicine
Inflammatory Bowel Disease, Ulcerative Colitis Type
A Multicenter Clinical Trial: Efficacy, Safety of Fecal Microbiota Transplantation for Inflammatory Bowel Disease
There are many limitations in the current treatments of Inflammatory bowel disease(IBD). Some patients have no or little reaction to the traditional drugs.
- Trial name
- NCT04521205
- Testing
- fecal microbiota capsule
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital Xiamen University