Clinical trials: Face
Bruxism, Face Pain
Effect of Cervical Manipulation on Mouth Opening
Objectives: To compare the effects of cervical manipulation on the ranges of motion of mouth opening and painful pressure points in the masseter and temporal muscles after of cervical manipulation compared to the control group.
- Trial name
- NCT05416788
- Testing
- cervical manipulation
- Where
- Chile
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Americas - Chili
Facial Wrinkles, Skin Hydration
Oral Supplementation With Active Collagen Peptides and Skin Health Improvement
The present study aims to investigate the efficacy of daily supplementation with COLLinstant® LMW over a 6-week period in improving visible signs of aging.
- Trial name
- NCT06321770
- Testing
- Bioactive collagen peptides
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Gala Servicios Clinicos S.L.
Peripheral Nerve Transections, Acute or Planned in Upper Extremity and Facial Nerves
NTX-001 to Repair Peripheral Nerve Transection(s)
The proposed use of NTX-001 for transections of upper extremity and facial peripheral nerves, acutely or planned.
- Trial name
- NCT05565846
- Testing
- NTX-001
- Where
- 2 sites in United States
- Sponsor
- Neuraptive Therapeutics Inc.
Maxillary Transverse Deficiency
Three-Dimensional Facial Soft Tissue Changes and Clinical Perception Following MARPE
This prospective, controlled observational study aims to evaluate three-dimensional (3D) facial soft tissue changes following miniscrew-assisted rapid palatal expansion (MARPE) and determine whether these changes are clinically…
- Trial name
- NCT07858370
- Testing
- Miniscrew-Assisted Rapid Palatal Expansion (MARPE)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Adiyaman University
Corneal Diseases
Ocular Surface Disorders in Patients in Intensive Care Units, a Comparative Study of Three Preventive Approaches
60% of the patients hospitalized in intensive care and sedated suffer from insufficient inferior eyelid occlusion. Thus, they are at risk for corneal damage (estimated risk 20% to 57%).
- Trial name
- OCUREA2 (NCT02348242)
- Testing
- Aqueous Gel, Eyelid Occlusion Dressing, Artificial Tears
- Where
- France
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Skin Manifestations
Tolerability Comparison of Differin® Cream 0.1% Versus Differin® Lotion 0.1% in Subjects With Healthy Skin
The purpose of this study is to compare the tolerability of Differin® (adapalene) Cream, 0.1% to Differin® Lotion, 0.1% in subjects with healthy skin treated once a day for three (3) weeks.
- Trial name
- NCT01046396
- Testing
- adapalene cream 0.1% and adapalene lotion 0.1%, adapalene lotion 0.1%
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06366503
- Testing
- Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Dynamic Wrinkles
ANTI-DYNAMIC LINE Test for Cream
The goal of this clinical trial is to find out whether a new cream (Formula# 899675 44A) can help reduce dynamic facial and neck wrinkles in young Chinese women.
- Trial name
- NCT07067073
- Testing
- Anti-Dynamic Line Cream
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Trigeminal Neuralgia
Pathophysiological Mechanisms of Trigeminal Neuralgia - Neurophysiological Assessment of the Blink-reflex
This study aims to increase the understanding of the pathophysiology of trigeminal neuralgia by investigating the potential association between blink reflex abnormalities and phenotypical traits e.g.
- Trial name
- TNBR (NCT05328661)
- Testing
- Blink reflex
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Headache Center
Actinic Keratosis
Controlled Study of the Occurrence of Actinic Keratosis on the Face After Cryotherapy + Aminolevulinic Acid (ALA) Photodynamic Therapy
The purpose of this study is to determine if Levulan photodynamic therapy (PDT) is safe and effective in the treatment of actinic keratoses (AK) on the face, following treatment with liquid nitrogen cryotherapy.
- Trial name
- NCT02239679
- Testing
- Aminolevulinic Acid, Topical Solution Vehicle, BLU-U
- Where
- 8 sites in United States
- Volunteers
- 166 people
- Sponsor
- DUSA Pharmaceuticals, Inc.
Facial Nerve Palsy
The Role of a Device to Evaluate the Neuromuscular Function in Assessing Muscle in Facial Paralysis Patients
The objective of the research is to determine whether the MyotonPRO has a valid and reliable application in facial, head and neck surgery. In addition, the study aims to compare this new technology with current electromyography.
- Trial name
- MyotonPRO (NCT02489162)
- Testing
- MyotonPRO, non-invasive electromyography (EMG)
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Photo-damaging
A Clinical Study to Evaluate the Efficacy and Satisfaction of the Skinceuticals Skin Care Product (CE) for Skin Repair Post Fraxel Laser Treatment
A Prospective, Single-center, Single-blind, Randomized split-face, controlled trial will be conducted. The goal of this clinical trial is to evaluate the efficacy and satisfaction of the Skinceuticals skin care product (CE) for…
- Trial name
- NCT05813483
- Testing
- Skinceuticals skin care product(CE), fraxel laser therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- DeYi Aesthetic Medical Clinic
Nasolabial Fold Correction, Facial Aging
Bridging Technique Validation for Nasolabial Folds JN-BRIDGE-1
The goal of this clinical study is to learn whether the Bridging Technique can safely and effectively treat nasolabial folds (NLF, also known as smile lines) in adults.
- Conditions
- Nasolabial Fold Correction, Facial Aging, Skin Rejuvenation, Wrinkles Such as Nasolabial Folds
- Trial name
- BRIDGING (NCT07178119)
- Testing
- (Bridging) Horizontal Cannula Technique for Treatment of Nasolabial Folds using AILEENE Vol. 2
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Joseph M Novoa Libermann
Aesthetic
"Profile HIT" (Holistic Individualized Treatment)
The "Holistic Individualized Treatment" (HIT) approach is used to identify treatment priorities, focus areas, and appropriate products for soft tissue filler treatments.
- Trial name
- HIT-PRF (NCT05819502)
- Testing
- Restylane line of injectables
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Facial Pain, Comorbidity
Somatosensory Investigation of Orofacial Pain Patients
Orofacial pain, specially neuropathic orofacial pain, is a challenge of diagnosis and treatment in orofacial pain. It is associated with sensory abnormalities.With increasing life expectancy of the population is more and more…
- Conditions
- Facial Pain, Comorbidity, Neuralgia
- Trial name
- QST (NCT02910336)
- Testing
- Quantitative Sensory Testing
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Acne Scars - Atrophic
Stromal Vascular Fraction Enriched PRP in Treatment of Post-acne Scars
in a split face fashion, 30 patients will be randomized into 3 groups: Group A: rt side treated with SVF enriched PRP, lt side treated with prp Group B: rt side treated with SVF enriched PRP, lt side treated with SVF Group C: rt…
- Trial name
- NCT06524011
- Testing
- Stromal vascular fraction (SVF) enriched platelet rich plasma (PRP) versus each alone
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Healthy Volunteers
Investigate the Change in Facial Pain Threshold During Auricular Acupuncture in Healthy Volunteers
Background: The effects and biological mechanisms of auricular acupuncture on the human body have been increasingly observed in clinical and experimental studies, particularly the analgesic effects.
- Trial name
- NCT05213299
- Testing
- AURICULAR ACUPUNCTURE
- Where
- Vietnam
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bui Pham Minh Man
Trigeminal Neuralgia
Analgesic Effect of Ultrasound Guided Maxillary Nerve Block in Trigeminal Neuralgia
This is a study about the dynamics and effects of ultrasound guided maxillary nerve block in trigeminal neuralgia
- Trial name
- NCT06129071
- Testing
- US guided block of maxillary nerve
- Where
- Croatia
- Sponsor
- Varazdin General Hospital
Bell Palsy
EFFECTİVENESS OF PULSED ULTRASOUND TREATMENT ON PATIENTS WITH BELL'S PALSY
Bell's palsy (idiopathic facial palsy) is the most common peripheral lesion of the cranial nerves and the most common mono-neuropathy.
- Trial name
- NCT04412733
- Testing
- Therapeutic Pulsed Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Trigeminal Neuralgia (TN), Orofacial Pain
Identification of Possible Trigeminal Neuralgia
Trigeminal neuralgia (TN) is a severe type of non-dental orofacial pain that can feel like sudden electric shocks in the face and is often mistaken for tooth pain or other dental problems.
- Conditions
- Trigeminal Neuralgia (TN), Orofacial Pain, Dental Pain, Questionnaire
- Trial name
- IDTN (NCT07453511)
- Testing
- Completion of the IDTN Questionnaire
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University College, London
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