Clinical trials: Facial Aging, active
Wrinkles, Anti Aging
PER-SAF_PDOS (Performance and Safety of Polydioxanone Suture)
This clinical investigation aims to confirm the safety and efficacy of the ID in facial soft tissue reconstruction, specifically for non-incision surgery to tighten and lift the facial skin for a rejuvenated facial appearance.
- Conditions
- Wrinkles, Anti Aging, Face-lift
- Trial name
- PER-SAF_PDOS (NCT07068061)
- Testing
- PDO suture
- Volunteers
- 50 people
- Sponsor
- 21 Century Medical Co., Ltd.
Skin Aging, Dry Skin
Effects of Probiotics on Skin Health in Healthy Women
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Trial name
- NCT07887841
- Testing
- Probiotics
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Probi AB
Facail Skin Aging
Facial Exercise and Daily Habit Modification Program for Skin Quality and Wrinkle Severity in Middle-Aged Women
This randomized controlled trial will evaluate the effectiveness of a 12-week program combining facial muscle exercises and daily habit modification for improving skin quality and reducing wrinkle severity in middle-aged women.
- Trial name
- NCT07792460
- Testing
- Facial Exercise and Daily Habit Modification Program
- Where
- Iraq
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Facial Skin Aging, Facial Volume Loss
Comparing Facial Aging Between Identical Twins With 3D Imaging
Identical twins share the same genes, which makes them a powerful way to study how lifestyle and environment - rather than genetics - affect how faces age.
- Conditions
- Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
- Trial name
- NCT07760532
- Testing
- GLP-1 Receptor Agonists
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ponsky Facial Aesthetics And Plastic Surgery, Llc
Quality of Life, Breast Neoplasms
Improved Facial Skin Quality and Quality of Life After VYC-12L Treatment in Breast Cancer Survivors
Systemic treatments such as chemotherapy or monoclonal antibodies are an essential part of oncological treatment in breast cancer, which have demonstrated a survival benefit (1,2,3,4,5).
- Conditions
- Quality of Life, Breast Neoplasms, Skin Aging, Hyaluronic Acid
- Trial name
- ONCO AESTHETIC (NCT07917117)
- Testing
- Intradermal injection
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Facial Aging, Skin Laxity
Quantified Evaluation of Noninvasive System Delivering Microwave Energy for Unwanted Fat Reduction and Skin Tightening in Asians.
The goal of this observational study is to evaluate the effectiveness and safety of microwave-assisted heating technology in facial fat reduction and skin tightening in Asians. The main questions it aims to answer are: 1.
- Conditions
- Facial Aging, Skin Laxity, Cheek Wrinkles
- Trial name
- NCT06925074
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chang Chang Cheng
Facial Skin Aging and Wrinkle Severity
Antioxidant Nutrition and Facial Exercise for Skin Aging
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women.
- Trial name
- NCT07792447
- Testing
- Combined Antioxidant Nutrition and Facial Exercise Program
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Skin, Skin Ageing
Clinical Trial to Assess the Efficacy and Safety of a Cosmetic Product in Individuals Showing Signs of Cutaneous Aging.
This clinical study investigates the effects and safety of a topical cosmetic product containing postbiotics (Bifida ferment extract and Pediococcus ferment extract) in women aged 35-60 with visible signs of skin aging.
- Conditions
- Skin, Skin Ageing, Fine Lines, Face Aging/Photo Aging of Moderate Grade
- Trial name
- SkinMeter (NCT07343544)
- Testing
- Active cream
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Aesthetic Procedures, Cosmetic Techniques
MENA Consensus on Poly-L-Lactic Acid (PLLA) Biostimulator Use in Aesthetic Dermatology
This study aims to develop expert consensus on the safe and effective use of poly-L-lactic acid (PLLA) biostimulators in aesthetic dermatology across the Middle East and North Africa (MENA) region.
- Conditions
- Aesthetic Procedures, Cosmetic Techniques, Skin Aging, Rejuvenation
- Trial name
- NCT07261748
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Research Center
Pain, Aging
RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)
This is a randomized, controlled, double-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA® Redensity with new anesthetic agent is non-inferior to RHA® Redensity with lidocaine in…
- Trial name
- NCT06378086
- Testing
- RHA® Redensity with new anesthetic agent, RHA® Redensity with lidocaine
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Aging, Dry Skin
Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Aging
This is a single-center, double-blinded, placebo-controlled, split-face, prospective clinical study to evaluate the anti-ageing efficacy and safety of a topical cosmetic formulation containing a botanical extract.
- Trial name
- NCT07780799
- Testing
- Cosmetic Topical Formulation 1, Cosmetic Base of Topical Formulation 1, Cosmetic Topical Formulation 2
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Photodamage of the Face, Anti Aging
Evaluation of the Efficacy and Tolerability of the LED Mask With or Without the Serum Formula on the Signs of Facial Photodamage .
Main objective : To evaluate the anti-aging effectiveness of the LED mask alone on at least one studied anti-aging parameters (including some targeted wrinkles) after 3 months versus baseline Secondary objectives: Anti-aging…
- Trial name
- NCT07661004
- Testing
- MASK LED, LED MASK AND COSMETIC FORMULA
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- L'Oreal
Aging, Facial Aging
Artificial Intelligence-Based Health Assessment From Face Photographs - Healthy Volunteer Study
The investigators aim to examine how FaceAge estimates (a measure of biological age based on facial features) change across different time points and identify factors that may influence these changes.
- Trial name
- FaceAge (NCT07719049)
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Skin Aging
Ultraformer MPT Combined With Fractional CO2 Versus Fractional CO2 Alone for Facial Rejuvenation
This pilot study compares fractional CO2 laser resurfacing alone with the same laser combined, in the same session, with micro-focused ultrasound (Ultraformer MPT) for signs of facial skin aging in women aged 50 to 65.
- Trial name
- ULTRA-CO2 (NCT07896512)
- Testing
- Ultraformer MPT, SmartXide Tetra Pro fractional CO2 laser
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinique Face MD
Facial Aging, Wrinkles
Effect of Single Facial Acupuncture on Dermal Structure and Appearance Satisfaction
This study aims to investigate the effects of a single session of facial rejuvenation acupuncture on skin structure and personal satisfaction with facial appearance.
- Conditions
- Facial Aging, Wrinkles, Skin Aging
- Trial name
- FRA (NCT07664280)
- Testing
- Facial Rejuvenation Acupuncture (FRA)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Skin Aging
Study on Safety and Efficacy of Monopolar Radio Frequency Device for Facial Skin Tightening
Objective: The goal of this clinical trial is to evaluate the safety and efficacy of the VOLNEWMER monopolar radiofrequency device developed by CLASSYS Inc.
- Trial name
- NCT06816069
- Testing
- VOLNEWMER
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Hair Care, Hair Loss
Olistic_2025 for Hair Loss, Hair Growth, and Skin Improvement
The goal of this randomized, double-blind, placebo-controlled clinical trial is to find out whether daily oral intake of the nutraceutical Olistic Next Women can reduce hair loss, improve hair growth and quality, and improve…
- Conditions
- Hair Care, Hair Loss, Female Pattern Hair Loss
- Trial name
- NCT07300813
- Testing
- Olistic Next Women
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bionos Biotech S.L.
Skin, Skin Microbiome
Examine Impact of Topical Application of Active Versus Placebo on the Skin Microbiome in Sensitive Skin.
The purpose of this study is to build insights to understand how the placebo and active impacts the skin microbiome in women with high skin sensitivity (SS10 > 13) and sun exposure.
- Conditions
- Skin, Skin Microbiome, Skin Microbiota, Skin Ageing
- Trial name
- SkinBiome (NCT07454525)
- Testing
- Active Cream
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Facial Wrinkles, Skin Aging
Evaluation of MD60002 Device for Facial Skin Aging
This single-center, non-controlled, single-arm clinical study is designed to evaluate the performance and safety of the Class III investigational device MD60002 (composed of highly purified polynucleotides at 3%) for aesthetic…
- Conditions
- Facial Wrinkles, Skin Aging, Skin Imperfections
- Trial name
- CIP-02-25 (NCT07881926)
- Testing
- Device: MD60002
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Promoitalia Group Spa