Clinical trials: Feasibility Study
Mitral Valve Regurgitation
Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Using Carbon 11(C-11) Acetate Cardiac Positron Emission Tomography Magnetic Resonance Imaging (PET-MRI)
The aim of this pilot imaging study is to investigate the underlying changes in myocardial oxidative metabolism, myocardial inflammation and alterations in extracellular volume in patients with chronic compensated moderate-severe…
- Trial name
- NCT04795856
- Testing
- [11C] acetate
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Validation
Validity and Feasibility of Newborn Bed Monitoring Device - a Clinical Pilot Study
The aim of this clinical pilot study is to evaluate the validity, acceptability and usability of the newborn bed monitoring device among newborns, parents and healthcare professionals in hospital environment.
- Trial name
- NCT06679127
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Anna Axelin
Healthy Volunteers
Safety and Feasibility of St. Mark's Electrode for the Hypoglossal Nerve and Cortico-lingual Pathway Study
The possibility of registering the M-response and the motor evoked potential (MEP) from the muscles of the tongue by using the St. Mark's electrode will be evaluated. The safety of method will be confirmed.
- Trial name
- NCT05070273
- Testing
- Hypoglossal nerve conduction study, Transcranial magnetic stimulation of hypoglossal nerve
- Where
- Russia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Dental Fear
Dental Fear Among Children With Autism Spectrum Disorders
Specific Aims Our study objective is to investigate if video peer modeling before the visit, plus immersive virtual reality during a preventive dental visit, reduces dental fear and uncooperative behaviors among children with…
- Trial name
- NCT01784276
- Testing
- Video
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cancer Survivors, African Americans
Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors
This pilot study will assess the feasibility of a gratitude intervention to promote physical activity, and well-being and positively impact biomarkers of health among older African American breast cancer survivors.
- Conditions
- Cancer Survivors, African Americans, Women, Psychology, Positive
- Trial name
- NCT05473026
- Testing
- Gratitude Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pregnancy Related
Feasibility and Acceptability of Butterfly iQ
The purpose of this study is to investigate feasibility and acceptability of a novel intervention to integrate Butterfly IQ into antenatal care (ANC) service delivery in Malawi.
- Trial name
- FAB-IQ (NCT05054504)
- Testing
- Butterfly iQ
- Where
- Malawi
- Volunteers
- 1,575 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Charcot-Marie-Tooth Disease, Type IA
BALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth Disease
Charcot Marie Tooth (CMT) is the most common inherited neuropathy. It affects the nerves of the hands and feet first, slowly progressing towards the centre of the body.
- Trial name
- BALTiC (NCT02982343)
- Testing
- Falls management plus exercise training, Falls management only
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Aged
The Umeå High-Intensity Training Study
This randomized controlled trial will evaluate the effect of high-intensity training (HIT) in older sedentary people. Seventy older people, aged 65 and over, will be randomized to HIT or moderate-intensity continuous training…
- Trial name
- Umeå HIT (NCT03765385)
- Testing
- High-intensity training, Moderate-intensity continuous training
- Where
- Sweden
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Umeå University
Stoma
Lipomodelling for Symptomatic Peri-stomal Skin Contour Abnormalities: a Pilot and Feasibility Study
In this study a technique called 'lipomodelling' is being studied to find out if it is beneficial around the stoma site in patients who have difficulty with securing their stoma bags which may lead to leakage and frequent soiling…
- Trial name
- LiSPA (NCT02090985)
- Testing
- Lipomodelling of symptomatic peri-stomal skin contour abnormalities
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Sussex Hospitals NHS Trust
Low Tidal Volume Ventilation
A Feasibility Study of a Low Tidal Volume Ventilation Strategy in One Lung Ventilation
A study of two ventilatory strategies for low tidal volume ventilation compared to a control group to elucidate if low tidal volumes of 3ml/kg or 4ml/kg were feasible for one lung ventilation.
- Trial name
- NCT03467607
- Testing
- tidal volume ventilation
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Hypovitaminosis D
Comparing a Novel Phototherapy Kiosk to Oral Vitamin D Supplementation
The purpose of this project is to demonstrate the capability of a standing phototherapy kiosk (SPK) to stimulate cutaneous vitamin D3 and subsequent production of 25 Hydroxyvitamin (OH) D safely and as efficiently as an oral…
- Trial name
- NCT04556136
- Testing
- Standing Phototherapy Kiosk, D3 Oral supplement
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Contraception Behavior, Sexual Behavior
Evaluating the Impact of CHOICE-AYA on Contraceptive Use, Continuation and Satisfaction
This is a prospective study involving two phases: 1) adaptation and 2) intervention, in adolescents aged 14-21 experiencing homelessness.
- Conditions
- Contraception Behavior, Sexual Behavior, Reproductive Behavior
- Trial name
- CHOICE-AYA (NCT05022134)
- Testing
- CHOICE-AYA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Deep Vein Thrombosis
Feasibility Study of Exercise in Patients With Leg Blood Clots
The purpose of this pilot study is to assess the feasibility of determining the effects of a structured exercise program started two to four weeks after diagnosis of a first episode lower-extremity deep vein thrombosis (DVT) for…
- Trial name
- EXPERT (NCT00910364)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Dementia Alzheimers
Feasibility Study of Game Technology in the Early Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
This study will test G:DATA, a simple computer game designed to diagnose Alzheimer's Disease, in three different groups of people, some of whom have Alzheimer's Disease.
- Trial name
- G:DATA (NCT06047340)
- Testing
- G:DATA, dementia screen videogame
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ascentys Ltd
Autism Spectrum Disorder
A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder
The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level…
- Trial name
- NAC (NCT03008889)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emory University
Retinopathy, Retinal Vein Occlusion
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
The objective of this study is to evaluate the safety and image quality of the investigational dye, MB-102, compared to the control dye (fluorescein sodium) in healthy and diseased eyes using fluorescent angiography for retinal…
- Conditions
- Retinopathy, Retinal Vein Occlusion, Diabetic Retinopathy, Macular Degeneration
- Trial name
- NCT04008121
- Testing
- Fluorescein sodium and Zeiss FF450 fundus camera, MB-102 and Zeiss FF450 fundus camera, Fluorescein sodium and commercially available optical angiography imaging system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Melanoma (Skin), Moles Multiple Benign
MoleGazer Development Feasibility Study
Melanoma (skin cancer) frequently develops from existing moles on the skin. Current practice relies on expert dermatologists being able to successfully identify new/changing moles in individuals with multiple moles.
- Trial name
- NCT05015816
- Testing
- Total body photography
- Where
- United Kingdom
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Type1diabetes
CGMIS 48-hour Feasibility Study
This is a single center, single arm non-randomized study of 48-hour CGMIS wear duration incorporating two meal-challenge tests to explore the performance of a single insertion combined glucose-sensing insulin delivery cannula.
- Trial name
- NCT05562206
- Testing
- CGMIS (Continuous Glucose Monitoring Infusion Set)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pacific Diabetes Technologies
Caregiver, Caregiver Mental Health
Friends/Family of Individuals at Risk of Suicide Training Program
The Friends/Family of Individuals at Risk of Suicide Training (FIRST) program is a six-week program designed to provide knowledge and practical skills to help caregivers care for their loved one while also supporting their own…
- Conditions
- Caregiver, Caregiver Mental Health, Caregiver Stress, Suicide
- Trial name
- FIRST (NCT07902089)
- Testing
- FIRST Program
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Prostate Cancer
The CArdiovascular Risk Evaluation in Men With Prostate Cancer Study (CARE-PC) Pilot Feasibility Study
The overarching goal of this trial is to develop mechanisms to improve cardiovascular care among such prostate cancer patients receiving ADT by increasing patient awareness of individualized cardiovascular risk estimates and…
- Trial name
- NCT06064149
- Testing
- CARE-PC Web-Based Application
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vivek Narayan
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