Clinical trials: Feasibility Study
Resistant Major Depression
Study of Transcranial Direct Current Stimulation (tDCS) as add-on Treatment for Resistant Major Depression
The purpose of the study is to investigate the effect of tDCS applied at the anodic left DLPFC of patients with resistant depression compared to patients treated with conventional therapy.
- Trial name
- DEPRESCO (NCT01428804)
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Hip Fracture Surgery, Mobility Limitation
Feasibility of a Co-designed Mobility Intervention After Hip Fracture Surgery
This clinical study examines whether a co-designed mobility intervention can be delivered in routine hospital care after hip fracture surgery.
- Conditions
- Hip Fracture Surgery, Mobility Limitation, Postoperative Rehabilitation
- Trial name
- HIP-ME-UP (NCT07561164)
- Testing
- HIP-ME-UP mobility intervention
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Hvidovre University Hospital
Single Chronic Wound, Lower Limb Wound
Telemonitoring of Chronic Wound Patients Using MyDerm, a Digital Solution: Feasibility Study
The aim of this study is to assess the feasibility of integrating myDerm for remote monitoring of chronic wounds into everyday practice, for patients over 18 years of age suffering from a single chronic wound of the lower limb…
- Trial name
- PIXAPROM (NCT06704087)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Pixacare
Hidradenitis Suppurativa
Mediterranean Dietary Intervention for HS
The goal of this clinical trial is to learn whether a 16-week Mediterranean-style dietary counseling program, called the Med-South Lifestyle Program (MSLP), is practical and acceptable for adults with hidradenitis suppurativa…
- Trial name
- HSMDS (NCT07800416)
- Testing
- Mediterranean Diet Counseling, Mediterranean Food Support
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Pre-Frailty, Aging
Exploratory Study on a Multi-nutrient Supplement and Exercise Program for Improving Health Markers Associated to Longevity in Pre-frail Adults
Frailty is associated with biological changes in the gut microbiome and immune system, along with marked declines in physical and cognitive function, leading to an overall reduction in quality of life.
- Trial name
- RtM (NCT07454616)
- Testing
- Supervised exercise program, a balanced micronutrient blend
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- National University of Singapore
Substance Use
Feasibility of Peer-mentor Delivered Substance Use Brief Intervention for Adolescents in Kenya
Adolescent substance use is prevalent in Kenya and in the US, and is associated with significant negative health and social outcomes.
- Trial name
- NCT05545904
- Testing
- Substance use brief intervention (BI), substance use education intervention
- Where
- Kenya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Moi University
Graft Patency
Study of Feasibility for Surgical Patients Undergoing Heart Surgery With the Mammary Arteries: Reviewing Infection, Occlusion Rates and Pain Assessments.
The Pilot study for the COMFORT Trial is a single centre trial to determine the feasibility of the full COMFORT Trial. The main COMFORT Trial will be a multi-centre trial to investigate the coronary artery bypass grafting…
- Trial name
- COMFORT pilot (NCT07599553)
- Testing
- Skeletonized vs non-skeletonized harvesting of the left internal mammary artery
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Cardiomyopathies, Skeletal Muscle Disorder
Observational Study on Cardiac Biomarkers Testing in Patients with Muscular Dystrophy Cardiomyopathy
The objective of this study is to evaluate acute changes of cardiac troponin (and other cardiac biomarkers) and mid-term biovariability in patients with cardiomyopathy associated with chronic skeletal muscle disease.
- Trial name
- KYMA (NCT05779202)
- Testing
- No intervention is planned.
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- University Hospital Heidelberg
Weight Gain During Pregnancy
BUMP2.0 Feasibility Study
Most women in the UK gain more weight than recommended during pregnancy, which puts them and their babies at risk of medical complications.
- Trial name
- NCT06882837
- Testing
- BUMP app
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Oxford
Healthy
A Pilot Feasibility Study of Detection of IL-11 and Other Cytokines in the Exhaled Breath Condensate (EBC) and Blood of Healthy Volunteers
IL-11 is a receptor previously proven to be highly expressed in human lungs with idiopathic lung fibrosis, and in animal model, IL-11 receptor neutralizing antibody has been shown to prevent the process of fibrosis in…
- Trial name
- NCT05536375
- Testing
- Exhaled breath condensate collection and blood draw
- Where
- Singapore
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Locally Advanced Rectal Carcinoma
Exercise for Improving Radiotherapy Efficacy in Rectal Cancer
This is a single arm feasibility study of exercise for improving short- course neoadjuvant radiotherapy efficacy in people diagnosed with locally advanced rectal cancer.
- Trial name
- NCT06292975
- Testing
- Supervised Vigorous intensity aerobic interval exercise
- Where
- United Kingdom
- Sponsor
- University of Hull
Anesthesia
Closed-loop Fluid Administration System: Pilot Study to Evaluate Feasibility
The investigators want to test during anesthesia the feasibility of a closed-loop automated fluid replacement system using cardiac output monitoring as the input value.
- Trial name
- NCT01882075
- Testing
- Open loop, Closed-loop
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hopital Foch
Multiple Myeloma
Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma
The purpose of the study is to determine the safety of MLN9708 as maintenance therapy following allogeneic stem cell transplant in patients with multiple myeloma.
- Trial name
- NCT02168101
- Testing
- MLN9708
- Where
- 4 sites in United States
- Volunteers
- 9 people
- Sponsor
- SCRI Development Innovations, LLC
Ovarian Cancer Stage IV, Peritoneal Cancer
Neo-adjuvant Pembrolizumab in Primary Stage IV Ovarian Cancer
This is a single arm feasibility study in patients with primary FIGO stage IV serous ovarian, peritoneal, or fallopian tube cancer to evaluate neo-adjuvant + adjuvant pembrolizumab for its capacity to induce and broaden T cell…
- Conditions
- Ovarian Cancer Stage IV, Peritoneal Cancer, Fallopian Tube Cancer
- Trial name
- NCT03126812
- Testing
- Carboplatin, Paclitaxel, Pembrolizumab
- Where
- Netherlands
- Volunteers
- 33 people
- Sponsor
- The Netherlands Cancer Institute
Symptomatic Irreversible Pulpitis
Full Pulpotomy in Mature Teeth With Symptomatic Irreversible Pulpitis as a Routine Treatment in the Primary Care Clinics
The present study has the objective of being a first approach of the full feasibility study in order to find out whether the Full Pulpotomy performed by a general practice dentist in a primary care dental clinic at the public…
- Trial name
- NCT05199181
- Testing
- Full pulpotomy
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- Rubén Domínguez Pérez
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
A Multicenter Feasibility Study With the VERAFEYE Imaging and Guidance System as Anatomical Navigation System
PRISM: A Multicenter Feasibility Study with the VERAFEYE Imaging and Guidance System as Anatomical Navigation System
- Trial name
- PRISM (NCT07686328)
- Testing
- Catheter Ablation
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Primary Progressive Aphasia, Frontotemporal Dementia
Better Living With Non-memory-led Dementia
This is a feasibility study on the effects of an online-based training and education programme for carers of people with posterior cortical atrophy (PCA), primary progressive aphasia (PPA) and behavioural-variant frontotemporal…
- Conditions
- Primary Progressive Aphasia, Frontotemporal Dementia, Alzheimer Disease
- Trial name
- NCT05525377
- Testing
- Better living with non-memory led dementia course
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University College, London
Acute Myocardial Infarction
PAclitaxel-eluting Balloon in Primary PCI in Amsterdam; Pilot Study
This clinical evaluation will study the feasibility and safety of a CE-marked paclitaxel-eluting balloon in primary PCI in patients with a STEMI.
- Trial name
- PAPPA-pilot (NCT01274728)
- Testing
- Percutaneous coronary intervention
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Kidney Cancer, Renal Cell Carcinoma
A Novel Haemostatic Agent for Robotic Partial Nephrectomy
Kidney cancer is one of only a few cancers with an increasing incidence over the past two decades. Renal cell carcinoma (RCC) accounts for over 85% of all kidney tumours, which makes up 2-3% of all adult malignancies.
- Trial name
- PuraBond (NCT07284953)
- Testing
- PuraBond
- Where
- United Kingdom
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Cognitive Impairment, Dementia
Older Adults With Cognitive Impairment Doing Sit to Stands, Walking in Transitional Care Programs: A Feasibility Study
The goal of this intervention study is to test the effects of a nurse-led mobility intervention (known as the OASIS Walking Intervention (Older Adults performing Sit to Stands and Walking Intervention)) in older adults with…
- Conditions
- Cognitive Impairment, Dementia, Delirium, Functional Decline
- Trial name
- OASIS (NCT06150339)
- Testing
- OASIS Walking Intervention
- Where
- 2 sites in Canada
- Volunteers
- 6 people
- Sponsor
- University Health Network, Toronto