Clinical trials: Febrile Urinary Tract Infection
Urinary Tract Infection, Fever
Treatment's Duration of Acute Uncomplicated Pyelonephritis
The purpose of this study is to compare the efficacy of 5 days versus 10 days treatment duration in uncomplicated acute pyelonephritis.
- Trial name
- DTP (NCT00873626)
- Testing
- levofloxacin, ciprofloxacin and ofloxacin (fluoroquinolones)
- Where
- 2 sites in France
- Volunteers
- 310 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urinary Tract Infection
Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants: a Pilot Study
The goal of this smaller clinical trial is to evaluate the study design of this research to help prepare for a larger research study in the future.
- Trial name
- STRUMI-T (NCT07508124)
- Testing
- betamethasone valerate 0.1% cream
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Hirschsprung Disease, Febrile Urinary Tract Infection (Disorder)
Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children
Febrile urinary tract infection (FUTIs) are the most common bacterial infections in children under the age of 2 years. They represent 7% of children presenting with fever without a source.
- Trial name
- NCT04837963
- Where
- France
- Volunteers
- 630 people
- Sponsor
- University Hospital, Montpellier
Urinary Tract Infections
Evaluation of the Plasmatic NGAL as a Predictive Marker of Renal Injury in Children With Urinary Infection. (Perf-NGAL-IU)
Urinary infections in children is very common. Delay in the diagnosis may be followed by complications. Pyelonephritis is a febrile urinary infection with a renal injury.
- Trial name
- Perf-NGAL-IU (NCT04191785)
- Testing
- plasmatic NGAl and MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Lenval
Posterior Urethral Valves
CIRCumcision and Urinary Tract Infections in Boys With Posterior Urethral Valves
Children with posterior urethral valves (PUV) are at risk of presenting febrile urinary tract infections (UTI). Circumcision has been shown to decrease the number of febrile UTIs in healthy children.
- Trial name
- CIRCUP (NCT01537601)
- Testing
- Circumcision, Antibiotic prophylaxis alone
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Urinary Tract Infections, Pediatric Disorder
Assessment of the Efficacy on the 5th Day of Antibiotic Therapy for Febrile Urinary Tract Infections Among Children From 3 Months to 18 Years Old
The main objective is to describe the rate of asymptomatic patients after 5 days of effective antibiotic therapy in an uncomplicated febrile urinary tract infection in children between 3 months and 18 years of age.
- Trial name
- PEDIU5 (NCT04667546)
- Testing
- Survey
- Volunteers
- 54 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Bladder Cancer, Transurethral Resection of the Bladder
Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial
The main objective of the study is to demonstrate that not performing a systematic UC before the TURB procedure is non-inferior to performing a systematic UC in terms of the incidence of febrile UTIs during the first 30…
- Conditions
- Bladder Cancer, Transurethral Resection of the Bladder, Urinary Tract Infection Bacterial
- Trial name
- RUPTURE (NCT07463963)
- Testing
- Urine bacterial Culture (UC), No intervention before TURB surgery
- Where
- 15 sites in France
- Volunteers
- 2,600 people
- Sponsor
- Poitiers University Hospital
Urinary Tract Infections in Children
7-day Compared With 10-day Antibiotic Treatment for Febrile Urinary Tract Infections in Children
The investigators aim to assess the effectiveness of a 7-day compared with a 10-day course of antibiotic treatment for febrile urinary tract infections (UTIs) in children.
- Trial name
- NCT03221504
- Testing
- Longer therapy duration, Shorter therapy duration
- Where
- 2 sites in Poland
- Volunteers
- 221 people
- Sponsor
- Medical University of Warsaw
Heart Failure, Chronic Obstructive Pulmonary Disease
Primary Care-Hospital Embedding: a Prospective, Multicentric, Observational Study
This is a multicentric, prospective, observational study with two cohorts and adjunctive procedure. It aims at collecting and analyzing data about the function of an innovative hospital-territory integration health service for…
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease, Diabetes Mellitus, Pneumonia
- Trial name
- PRIME (NCT05723185)
- Testing
- Outpatient visit
- Where
- Italy
- Volunteers
- 246 people
- Sponsor
- Rovere Querini Patrizia
Urinary Tract Infections
Disturbance of the Intestinal Microbiota by Temocillin vs Cefotaxime in Treatment of Febrile Urinary Tract Infections
This study will evaluate the ecological impact on the intestinal microbiota and compare the safety and efficacy of temocillin compared to cefotaxime, in empiric treatment of febrile UTI.
- Trial name
- NCT02959957
- Testing
- Temocillin, Cefotaxime
- Where
- 12 sites in Sweden
- Volunteers
- 157 people
- Sponsor
- Håkan Hanberger
Infective Complications Post-transrectal Prostate Biopsy
Prostate Biopsy Antisepsis
During a prostate biopsy, a needle is guided through the rectum into the prostate. Although patients are given antibiotics before the biopsy, there is still a risk of bacteria getting from the rectum into the bladder, prostate…
- Trial name
- NCT00999427
- Testing
- Povidone-iodine
- Where
- 3 sites in Canada
- Volunteers
- 865 people
- Sponsor
- University of British Columbia
Urinary Tract Infection, Unspecified Fever
Improvement in Urine Collection Methods in Children
The population of children presenting to the Emergency Department (ED) for treatment increases day by day, creating a further burden on the limited nursing staff and where many children and their parents are forced to wait many…
- Trial name
- 0244-12-RMC (NCT01895465)
- Testing
- Slitted diaper
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Rabin Medical Center
COVID-19, Infectious Disease
Continuous Temperature Telemonitoring of Patients With COVID-19 and Other Infectious Diseases in Hospital at Home Using Viture
The aim of this cohort study is to validate Viture®, a continuous temperature telemonitoring system, evaluating the level of agreement with a standard commercially available digital axillary thermometer.
- Conditions
- COVID-19, Infectious Disease, Tract Infection, Urinary, Bacteremia
- Trial name
- Viture (NCT05959928)
- Testing
- Continuous wearable thermometer placed on patient's armpit to monitor body temperature remotely
- Where
- Spain
- Volunteers
- 208 people
- Sponsor
- Vitio Medical S.L.
Urinary Tract Infections, Meningitis
Febrile Infant Diagnostic Assessment and Outcome Study
Febrile infants under 3 months of age represent a high risk group for invasive bacterial infection (IBI) and UTI with approximately 10-20% having bacteremia, meningitis or urinary tract infection.
- Conditions
- Urinary Tract Infections, Meningitis, Sepsis, Bacterial Infections
- Trial name
- FIDO (NCT05259683)
- Where
- United Kingdom
- Volunteers
- 2,076 people
- Sponsor
- Queen's University, Belfast
Acute Urinary Tract Infection, Urinary Tract Infection
Corticosteroids for Children With Febrile Urinary Tract Infections
In this study the investigators will determine whether corticosteroids given at the time of urinary tract infection help prevent permanent damage to the kidneys.
- Trial name
- STARRS (NCT01391793)
- Testing
- Dexamethasone
- Where
- 6 sites in United States
- Volunteers
- 546 people
- Sponsor
- Nader Shaikh
Procalcitonin, Fever Without Source
Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a Source
Serious bacterial infections are often difficult to detect in children with fever without source. Procalcitonin is a better blood marker of infection than White blood cell count and possibly than C-reactive protein.
- Conditions
- Procalcitonin, Fever Without Source, Bacterial Infection, Bacteremia
- Trial name
- NCT00692848
- Testing
- Procalcitonin dosage PCT-Q test (Brahms, Germany)
- Where
- Canada
- Volunteers
- 384 people
- Sponsor
- St. Justine's Hospital
Acute Pyelonephritis
Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection
Hypothesis: Administration of corticoids (dexamethasone) together with the conventional antibiotherapy in the acute phase of a febrile urinary tract infection could reduce the risk of renal scarring after 6 months of the…
- Trial name
- DEXCAR-0212 (NCT02034851)
- Where
- 7 sites in Spain
- Volunteers
- 183 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Fever Without Source
Impact of a PCT(Procalcitonin) Rapid Test -Based Approach on ATB (Antibiotics) Use in Children With Fever Without Source
Because a newly available point-of-care test may have real interest especially for children in the Emergency Department (ED) setting, by limiting painful and stressful venipunctures and decreasing the length of stay in the ED…
- Trial name
- DIAFEVER (NCT03607162)
- Testing
- DIAFEVER algorithm
- Where
- 26 sites in France, Switzerland
- Volunteers
- 4,928 people
- Sponsor
- Nantes University Hospital
Febrile Urinary Tract Infection
Pivmecillinam as Oral Step-Down Treatment for Escherichia Coli Febrile Urinary Tract Infection Versus Standard of Care
The goal of this clinical trial is to learn if oral treatment with pivmecillinam is effective to treat febrile urinary tract infections in adult patients.
- Trial name
- PIVOT (NCT07236944)
- Testing
- Pivmecillinam, Standard of Care (Investigator Choice)
- Where
- 13 sites in Norway, Sweden
- Volunteers
- 560 people
- Sponsor
- Uppsala University
Urinary Tract Infection Bacterial, Nephrolithiasis
Blood Parameters as a Predictor of Fever After Percutaneous Nephrolithotomy
To investigate the relationship between neutrophil count, lymphocyte count, neutrophil-to-lymphocyte count ratio (NLR), and postoperative fever in patients undergoing percutaneous nephrolithotomy (PNL).
- Trial name
- NCT03774940
- Testing
- peripheric blood count
- Where
- Turkey (Türkiye)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University