Clinical trials: Fertility
Pregnancy Complications, Contraception
Impact of the Microbiome on Time to Pregnancy and Pregnancy Outcomes in Fertile Women Attempting to Conceive
This study aims to investigate the microbiome of women with previously proven fertility who plan to become pregnant.
- Conditions
- Pregnancy Complications, Contraception, Pregnancy Loss, Fertility
- Trial name
- SweBioFertil (NCT05127252)
- Testing
- Vaginal and rectal microbiome and metabolome
- Where
- 2 sites in Sweden
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Healthy
A Study to Compare Two Different Tablet Formulations of AZD8931 in Healthy Males and Females
A study to compare two different tablet formulations of AZD8931 in healthy males and females.
- Trial name
- NCT01330758
- Testing
- AZD8931
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers
The primary purpose of this study is to assess the safety and tolerability of AZD1446 following single dose administration.
- Trial name
- SAD (NCT00803855)
- Testing
- AZD1446
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fertility, Fertility, Male
Plan A Occlusion and Reversal System Feasibility Study
Prospective, multicenter, single-arm, open label, interventional clinical trial investigating the safety and effectiveness of the Plan A Male Contraceptive System to occlude the vas deferens to block the passage of sperm and then…
- Conditions
- Fertility, Fertility, Male, Healthy Male Adults
- Trial name
- NCT07361120
- Testing
- Occlusion System
- Where
- 3 sites in Australia, Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Endometriosis, Infertility
Pesticides and Infertility: Oxidative Stress Via Circulating Cell-free DNA and Gut/Genital Microbiome Signatures in Women With Endometriosis
This project PestiEndoMicro aims to provide an innovative approach, studying endometriosis under the genital and gut microbiota scope.
- Conditions
- Endometriosis, Infertility, Female Fertility, Cell Free DNA
- Trial name
- PestiEndoMicro (NCT07471373)
- Testing
- Circulating DNA analysis, Vaginal microbiota analysis, Endometrial microbiota analysis
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cesarean Section Complications, Fertility Disorders
Uterine Inflammatory Characteristics
Data regarding fertility following niche repair is limited. It has been reported that a niche can reduce the chances of embryo implantation and may lead to spontaneous miscarriages if the implantation is close to or in the niche.
- Trial name
- NCT04747418
- Testing
- Diagnostic Hysteroscopy, Trans-vaginal ultrasound
- Where
- Israel
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Fertility
Usefulness of Home Pregnancy Testing
The objective of this study is to determine whether women in a Medicaid population at risk for unintended pregnancy will keep a home pregnancy test on hand and (if necessary) use it appropriately.
- Trial name
- NCT00390754
- Testing
- Education for pregnancy planning
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Fertility Disorders, Assisted Reproductive Technology
The Clinical Cohort Study of Reproductive Health
The study will conduct a multicenter prospective clinical cohort study to collect comprehensive health information and essential specimens from pre-pregnancy to postpartum offspring development.
- Conditions
- Fertility Disorders, Assisted Reproductive Technology, Offspring Health
- Trial name
- NCT05164029
- Testing
- Completion questionnaires/providing biological samples
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Effects of Chemotherapy
Ovarian Freezing Before Cancer Treatment
Women of reproductive age who will undergo cancer treatment may participate in a study to surgically remove ovarian tissue and store it, frozen, for their potential use in the future.
- Trial name
- NCT01057745
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Infertility
Online Mind/Body Program for Fertility
This pilot-study assesses the feasibility and acceptability of an Online Mind/Body Fertility Program, designed to help individuals and/or couples cope with the physical and emotional impact of infertility by learning special…
- Trial name
- NCT03343405
- Testing
- Online Mind/Body Program for Fertility
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Aneuploidy, Pregnancy
The Effect of Co Enzyme Q10 Together With Fertility Drugs on Pregnancy Outcome of in Vitro Fertilization
The goal of our research is to increase live birth rates in infertile women and to reduce the incidence of aneuploidy leading to miscarriage and trisomies.
- Conditions
- Aneuploidy, Pregnancy, Miscarriage
- Trial name
- CoQ10-IVF (NCT01048385)
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Genetic Disorder, Fertility Disorders
Retrospective Study on Clinical Results of Preimplantation Genetic Screening at Different Embryo Stage
Preimplantational genetic screen (PGS) is tool for diagnosis of embryo chromosome abnormality before transfer. Under this tool, patients with a family history of genetic disease or special genetic disease could avoid to produce…
- Conditions
- Genetic Disorder, Fertility Disorders, Reproductive Disorder
- Trial name
- NCT03065114
- Testing
- PGS
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yeh
Infertility
Improving Knowledge About Infertility; an Online Educational Tool
The purpose of this study is to determine the effectiveness of an online informational video in improving knowledge about infertility in couples experiencing problems conceiving.
- Trial name
- NCT01916356
- Testing
- educational video
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University
Predisposition, Genetic, Cancer
Investigating the Role of Genetics in Disease Predisposition
Gametogenesis is the production of sperm and eggs; it takes place through the process of meiosis. Gametogenesis is subject to the acquisition of mutations as with other processes in the body.
- Conditions
- Predisposition, Genetic, Cancer, Mutation, Fertility Disorders
- Trial name
- NCT06584994
- Testing
- sample collection
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Wellcome Sanger Institute
Fertility
Validation Study Using a Time-lapse Morphometry MIRI Imaging Incubator
The purpose of this study is to evaluate the safety and efficacy of the MIRI-TL time-lapse incubator and CultureCoin dish compared to standard big-box incubators and standard culture dishes used for embryo culture.
- Trial name
- TiMMI (NCT02852356)
- Testing
- MIRI-TL Incubator
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Reproductive Health
Fertility and Preconceptional Health Knowledge and Attitudes Among University Students
Fertility means being fertile, that is, having the ability to reproduce. Fertility awareness means that individuals know and avoid the anatomy and physiology of the reproductive system, the importance of fertility, fertility…
- Trial name
- NCT06254937
- Testing
- Reproductive Life Plan training
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ebru Cirban Ekrem
Fertility
Effect of Oocyte Vitrification on Fertilization Rate, Embryo Quality and Development
Indications for oocyte (egg) vitrification (fast freezing) include the preservation of reproductive competence of young cancer patients who need chemotherapy, pelvic radiation, or surgical removal of ovaries for treatment.
- Trial name
- NCT01422395
- Testing
- Freezing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Benign Ovarian Cyst
Intra-operative Ultrasound Guided Laparoscopic Ovarian Cystectomy as a Method of Fertility Preservation
Title: Intra-operative ultrasound guided laparoscopic ovarian cystectomy (UGLOC) as a method of fertility preservation in the management of benign ovarian cysts.
- Trial name
- UGLOC (NCT05032846)
- Testing
- Ultrasound guided laparoscopic ovarian cystectomy, Laparoscopic Ovarian Cystectomy
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Leiomyoma, Uterine
Fibroids and Infertility - a Study of the Significance of Removal of Fibroids With Regard to Endometrial Receptivity
We aim to explore some of the molecular factors that reduce fertility for women with leiomyomas, taking into account leiomyoma location, size, number and vascularity.
- Trial name
- FIN (NCT04426760)
- Testing
- Transcervical resection of fibroids, Myomectomy per laparoscopy or laparotomy
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital