Clinical trials: First Nations
Mental Health, Substance-Related Disorders
First Face Training Evaluation in Tribal Communities
The goal of this study is to evaluate a culturally grounded training curriculum, First Face for Mental Health, in Tribal communities, using a waitlist controlled trial design.
- Trial name
- NCT05998005
- Testing
- First Face Training Program
- Where
- 9 sites in United States
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Fall
Standing Strong in Tribal Communities: Assessing Elder Falls Disparity
Falls and fall-related injuries are major health risks in American Indian elders. The data showed 52 percent of Zuni elders reporting a fall during the past year, which is significantly higher than the US national average of one…
- Trial name
- NCT04876729
- Testing
- Otago Exercise Program
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Intervention Condition, Wait-List Control
Talking Circle for Native American Youth Living Well (AYoLi)
This study, "Talking Circle for Native American Youth Living Well (A Yo Li)" uses a Community Based Participatory Research (CBPR) approach to evaluate Talking Circle effectiveness, partnering with The American Indians in Texas at…
- Trial name
- AYoLi (NCT07746375)
- Testing
- Talking Circle Intervention, Wait-List Control Group
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Melessa Kelley
Substance Use Disorders
Drum-Assisted Therapy for Native Americans
Drum-Assisted Recovery Therapy for Native Americans (DARTNA) is an R-21 NIH/NCCAM-funded study aimed to complete the development and pilot a new substance abuse treatment protocol utilizing drumming for American Indians/Alaska…
- Trial name
- NCT01356667
- Testing
- DARTNA, Treatment-As-Usual
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Colorectal Cancer (CRC)
Raising Awareness of Colorectal Screening in American Indian Communities
This study focuses exclusively on American Indian individuals within their communities to enhance health equity and address a critical tribal health priority.
- Trial name
- AIC-DC (NCT07515729)
- Testing
- Navigator-led intervention
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Human Immunodeficiency Virus (HIV)
e-HERO: Ending the HIV Epidemic in Rural Oklahoma
The goal of this study is to increase HIV and syphilis testing and linkage to care, increase condom use, and promote PrEP uptake among sexual minority men (SMM) and American Indian (AI) men in rural Oklahoma, a state that is an…
- Trial name
- e-HERO (NCT05664802)
- Testing
- e-HERO: Ending the HIV Epidemic in Rural Oklahoma
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Smoking Cessation
Urban and Reservation Implementation of All Nations Breath of Life
This is an implementation trial of the All Nations Breath of Life (ANBL) smoking cessation program, which has already been tested for efficacy in reservation populations and shown feasibility in urban populations.
- Trial name
- ANBL-I (NCT04931810)
- Testing
- All Nations Breath of Life
- Where
- United States
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Alcohol Use Disorder
mHealth App for Changing Alcohol Use in Alaska Native American Indian People
For many people who have trouble with alcohol, peer support - the opportunity to share challenges, problem-solving strategies, and successes with supportive others - can be helpful.
- Trial name
- CIRCLE (NCT05326438)
- Testing
- CIRCLE mHealth app
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southcentral Foundation
LGBTQ, Racial Disparities
Lakota Family Acceptance Project
The goal of this open pilot trial (OPT) is to develop a Lakota-adapted Family Acceptance Project (LFAP) for Indigenous 2SLGBTQ+ youth and their caregivers.
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP OPT (NCT07326748)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Early Childhood Caries
Happy Teeth for Hopi Tots: Cultural Adaptation of an Oral Health Entertainment-Education Intervention
Tooth decay is a preventable disease occurring at high rates among American Indian (AI) populations. The use of entertaining educational materials and cultural adaptation have shown success in improving health behaviors.
- Trial name
- NCT05297526
- Testing
- Culturally adapted children's book, Standard informational brochure on children's oral health
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northern Arizona University
Access to Health Care
Improving Native American Elder Access to and Use of Healthcare
This community-driven study features a mixed-method, participatory design to examine help-seeking behavior and healthcare experiences of American Indian elders in New Mexico, in order to develop and evaluate a tailored…
- Trial name
- NCT03550404
- Testing
- Seasons of Care App
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Type 2 Diabetes, Food Insecurity
The Food for Health Study
The project, called Food for Health (F4H), will study a new Produce Prescription Program (PPP) designed for rural Native American older adults.
- Conditions
- Type 2 Diabetes, Food Insecurity, Rural Health
- Trial name
- F4H (NCT07254689)
- Testing
- Produce Prescription Program
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Montana
Diabetic Nephropathy, Diabetes Mellitus
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease.
- Conditions
- Diabetic Nephropathy, Diabetes Mellitus, Diabetic Kidney Disease, Albuminuria
- Trial name
- NCT00342927
- Where
- United States
- Volunteers
- 9,084 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diet, Healthy, Physical Activity
It's Native: Nudging Healthy Ways
Native Americans suffer disproportionately from chronic diseases that may be prevented by achieving a healthy diet, physical activity and weight.
- Trial name
- NCT05470296
- Testing
- Move & Eat 2 Live
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Southern Mississippi
Early Childhood Caries, Dental Caries
Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project
The purpose of this study is to determine whether a bundled best practices oral health intervention utilizing motivational interviewing versus a didactic maternal and child healthy lifestyle intervention will reduce childrens'…
- Trial name
- NCT04556175
- Testing
- Oral Health, Healthy Lifestyle
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Alcohol Use, Marijuana Use
Motivational Interviewing and Culture for Urban Native American Youth (MICUNAY)
The investigators plan to develop and test a new alcohol and other drug (AOD) intervention for urban AI/AN youth, "Motivational Interviewing and Culture for Urban Native American Youth (MICUNAY)." This intervention integrates…
- Trial name
- MICUNAY (NCT02290938)
- Testing
- MICUNAY, Community Wellness Gathering
- Where
- 2 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- RAND
Lung Carcinoma
An Educational Intervention (Lung Toolkit) for Improving Knowledge About Lung Cancer and Screening Among American Indian and Alaskan Native Cigarette Smokers, Lung PATHS Trial
This clinical trial evaluates the acceptability and effectiveness of an educational intervention (Lung Toolkit) for improving knowledge about lung cancer and lung cancer screening among American Indian/Alaskan Native (AI/AN)…
- Trial name
- NCT07615764
- Testing
- Educational Intervention, Interview, Questionnaire Administration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
LGBTQ, Racial Disparities
Lakota Family Acceptance Project Pilot RCT
Although research documents the concerning rates of mental and behavioral health problems (e.g., substance use/initiation) among Indigenous LGBTQ2S+ youth, there is very little known about how to prevent these deleterious issues…
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- L-FAP (NCT07865858)
- Testing
- Adapted Lakota Family Acceptance Program
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Stress, Depression
Polarity Therapy for American Indian Caregivers of Dementia Patients
The purpose of this study is to assess the effectiveness of polarity therapy (PT), a complementary and alternative medicine treatment, in American Indian caregivers living in the Pacific Northwest.
- Conditions
- Stress, Depression, Anxiety
- Trial name
- NCT00100035
- Testing
- Polarity therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Cardio Vascular Disease, Cerebro Vascular Disease
Qungasvik (Toolbox)-Healthy Hearts: A Cultural Approach to Reducing Chronic Disease Risk
Due to the extreme remoteness, transportation challenges, and lack of access to clinical care, the delivery of preventative health interventions in rural Alaska Native communities is a top tribal priority.
- Conditions
- Cardio Vascular Disease, Cerebro Vascular Disease, Mental Health, Chronic Disease (Physical)
- Trial name
- AK CEAL EI (NCT07829341)
- Testing
- Qungasvik-Healthy Hearts
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks