Clinical trials: Fluency Disorder
Alzheimer's Disease, MCI Due to AD
Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease
The goal of this observational cross-sectional study is to explore the characteristics of language, speech, and motor function in persons with Mild Cognitive Impairment due to Alzheimer's disease ("MCI due to AD") and persons…
- Conditions
- Alzheimer's Disease, MCI Due to AD, Dementia Alzheimers
- Trial name
- NCT06508268
- Testing
- GAITRite walkway system OR 4-meter walking speed test, Jamar hand dynamometer, Picture description task
- Where
- Netherlands
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Hanze University of Applied Sciences Groningen
Aphasia
Based on the Spatio-temporal Coding Characteristics of Frontotemporal Network, This Paper Explores the Mechanism of Five-tone Speech Training in Reshaping Language Fluency Function.
To explore the mechanism of five-tone speech training in reshaping language fluency function and the clinical efficacy of aphasia language function, daily communication ability and communication efficiency based on the temporal…
- Trial name
- NCT07329751
- Testing
- Traditional Chinese Medicine Five-Tone Therapy, Melodic Intonation Training, Standard speech therapy; Routine medical treatment; Health education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian University of Traditional Chinese Medicine
Stuttering, Developmental
Investigating Non-invasive Brain Stimulation to Enhance Fluency in People Who Stutter
This study aims to test whether the application of transcranial direct current stimulation (tDCS) concurrent with fluency training results in improvements in speech fluency in adults with developmental stuttering, measured up to…
- Trial name
- INSTEP (NCT03335722)
- Testing
- Metronome-timed speech, Active tDCS
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Parkinson Disease
The Efficacy and Safety of Transcutaneous Auricular Vagus Nerve Stimulation for Depression in PD
This study is a double blind comparative study examining the effectiveness of the transcutaneous auricular vagus nerve stimulation treatment on Parkinson's disease patients with depression.
- Trial name
- PD-D-taVNS (NCT07679529)
- Testing
- Active Transcutaneous auricular vagus nerve stimulation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Stuttering, Adult
Investigating the SMA's Role in Speech and Reading Fluency in PWS With rTMS
The goal of this clinical trial is to study how a part of the brain called the supplementary motor area (SMA) is connected to speech and reading fluency in adults who stutter.
- Trial name
- NCT06809387
- Testing
- Brain stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Medipol University
Brain Disorder, Healthy
Differences in Brain Processing of First and Second Languages (Korean and English)
This study will examine differences in how the brain processes English and Korean in native Korean speakers who are fluent and non-fluent in English as a second language.
- Trial name
- NCT00016510
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stuttering
The Effects of Tactile Speech Feedback on Stuttering Frequency
The purpose of this research project is to test the effects of exposure of different forms of tactile speech feedback on overt stuttering frequency.
- Trial name
- NCT01315730
- Testing
- Tactile Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Mississippi, Oxford
Voice, Speech
Virtual Reality as a Tool for Training Public Speaking Skills in Higher Education Students
According to the scientific literature, public speaking (PS) is an important skill for students to master. However, a large proportion of students do not feel comfortable speaking in public.
- Conditions
- Voice, Speech, Virtual Reality Simulation, Healthy Adult
- Trial name
- NCT07392554
- Testing
- Indirect Method, Direct Method
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Liege
Parkinson's Disease, Deep Brain Stimulation
The Effect of Electrode Implantation for Deep Brain Stimulation (DBS) on Brain Function Using Single Photon Emission Computed Tomography (SPECT) With Technetium-99m-ethyl Cysteinatedimer (Tc-ECD)
The goal of this study is to explore the effect of subthalamic nucleus (STN)-DBS surgery and stimulation in PD (Parkinson's disease) patients on regional cerebral blood (CBF) flow during cognitive task performance or at rest.
- Trial name
- NCT01037686
- Testing
- Injection of 15mCi of Tc-ECD and scanning by SPECT camera, Semantic verbal fluency task performance, Turning off the stimulator
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Autism Spectrum Disorders, Autism
Measurement of Joint Attention Fluency
The purpose of this research is to study joint attention. Joint attention plays a critical role in social and language development in children with and without autism.
- Trial name
- NCT01643343
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Vista School
Stuttering, Adult
Bihemispheric Transcranial Direct Current Stimulation* on Speech Fluency
It will be determined whether bihemispheric stimulation (anodal to the left IFG and cathodal to the right IFG) is used with fluency-facilitating conditions for 5 consecutive days in individuals with stuttering and whether there…
- Trial name
- TDCS (NCT06278233)
- Testing
- Transcranial direct current stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Biruni University
Stammering
Modifying Unconscious Tongue Movements in Adults With Developmental Stammer.
This is a pilot randomised controlled trial investigating whether using modification of saccadic eye movements can control lateral unconscious tongue positioning and enhance fluency in adults with a confirmed developmental…
- Trial name
- NCT04310436
- Testing
- Modifying saccades by looking down to naval., Modifying saccades by looking in air.
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Technology, Sligo
Word Finding Difficulty, Communication Disorders
Intervention for Fluency Difficulty
The focus of the study is to identify children with word-finding difficulty and other speech and communication difficulties such as stuttering, a procedure referred to as screening.
- Trial name
- FIST (NCT04217460)
- Testing
- Intervention for fluency difficulty
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College, London
Stuttering, Adult
Dopamine and Sensorimotor Function in Stuttering
This study is being done to understand the effect of aripiprazole on adults who stutter. Stuttering is a disorder that affects speech fluency.
- Trial name
- NCT07215884
- Testing
- Aripiprazole 10 MG
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Normal Non-fluency
Effect of Short Term Atypical Antipsychotic Administration Compared to Placebo on Hepatic Insulin Extraction
Within the past 20 years, there has been a striking increase in the incidence of obesity 1;2, type 2 diabetes mellitus (T2DM) 3-5, and cardiovascular diseases (CVD) in the schizophrenic population 6-8 .
- Trial name
- NCT02447835
- Testing
- Olanzapine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Michael Rickels
Parkinson's Disease
Evaluation of Intensive Language Therapy
Due to Parkinson's Disease (PD) speech and language (SL) deficits may occur. Further, the literature reports that PD patients, who have not undergone deep brain stimulation (DBS), have deficits regarding voice quality (e.g.
- Trial name
- EILT (NCT02935842)
- Testing
- Specific SL-therapy, Rhythmic Balance-Movement Training (rBMT)
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Aphasia, Apraxia of Speech
Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia
Speaking in unison with another person is included as a part of many treatment approaches for aphasia. It is not well understood why and how this technique works.
- Trial name
- NCT05248295
- Testing
- Unison speech (vs. solo), Metrical timing (vs. conversational)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Major Depressive Disorder Remission, Major Depressive Disorder
Vulnerability Markers for Depression
The current study is a pilot for the GRF project entitled "Predicting illness trajectories in fully remitted major depression using concurrent TBS/fNIRS".
- Conditions
- Major Depressive Disorder Remission, Major Depressive Disorder, Healthy
- Trial name
- NCT06402422
- Testing
- Theta-burst stimulation
- Where
- Hong Kong
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Apraxia of Speech, Aphasia
Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech
Impaired speech production is a major obstacle to full participation in life roles by stroke survivors with aphasia and apraxia of speech.
- Conditions
- Apraxia of Speech, Aphasia, Cerebrovascular Accident
- Trial name
- NCT02094014
- Testing
- Normal Auditory Feedback, Masked Auditory Feedback, Altered Auditory Feedback
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Stuttering
Shaping Motor Neural Functioning of Developmental Stuttering to Improve Fluency
Developmental stuttering (DS) is a motor/speech disorder, characterized by specific alterations in the functioning of brain circuits.
- Trial name
- NCT05306782
- Testing
- transcranial Electrical Stimulation, Speech Therapy
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy