Clinical trials: Fluid Output
Pleural Effusion Recurrence, Pulmonary Resection
Evaluation of Fluid Output Threshold for Safe Chest Tube Removal - A Potential Way to Decrease Length of Stay in Hospital and to Improve Postoperative Care After Lung Surgery?
Previous studies have shown that the removal of the chest tube after lung surgery significantly improves pain symptoms and lung function.
- Conditions
- Pleural Effusion Recurrence, Pulmonary Resection, Chest Tube Management
- Trial name
- NCT03093610
- Testing
- Traditional, Test
- Where
- Switzerland
- Volunteers
- 337 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Circulatory Failure
Time Course Evolution of Cardiac Output
Fluid expansion is the first therapeutic option in patients presenting acute circulatory failure but the duration of its hemodynamic effects (persistency and time of maximal increase in cardiac output) is unknown.
- Trial name
- TCCO (NCT03694717)
- Testing
- Saline Solution for Injection
- Volunteers
- 58 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Fluid Responsiveness Predictability in Sepsis
A Study Comparing Carotid Doppler Ultrasound and Echocardiography to Assess Fluid Responsiveness in Septic Patients on Ventilator
The goal of this clinical trial is to determine whether common carotid artery blood flow measured by bedside Doppler ultrasound can accurately identify fluid responsiveness in mechanically ventilated adults with sepsis.
- Trial name
- NCT07653568
- Testing
- intravenous crystalloid fluid bolus
- Where
- Pakistan
- Volunteers
- 94 people
- Sponsor
- Pakistan Institute of Medical Sciences
Body Fluid Retention, Impedance
Effect of Passive Leg Raising for Fluid Responsiveness
Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 …
- Conditions
- Body Fluid Retention, Impedance, Cardiac Output, Low
- Trial name
- NCT02702544
- Testing
- CardioScreen 1000 - Haemodynamic Measurement System, Medis, SCHILLER, BR-102 plus - Ambulatory Blood Pressure Monitoring System
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Fluid Overload
Furosemide Versus Ethacrynic Acid in Children With Congenital Heart Disease
This study aims to verify if ethacrynic acid continuous infusion is superior to furosemide continuous infusion in total urine output production during the first 24 post operative hours.
- Trial name
- NCT01628731
- Testing
- furosemide, ethacrynic acid
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
USCOM, Echocardiography
Comparison of the Ultrasonic Cardiac Output Monitor and Echocardiography for Hemodynamic Assessment in Pediatric Anesthesia
This prospective observational pilot study evaluates agreement between Ultrasound Cardiac Output Monitor (USCOM) measurements and transthoracic echocardiography-derived hemodynamic parameters in pediatric patients under…
- Conditions
- USCOM, Echocardiography, Echocardiography Guided Fluid Management
- Trial name
- NCT07342842
- Testing
- USCOM, Echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Shock
The Use of LiDCOplus in Fluid Resuscitation Decision-Making
Unwell patients in the intensive care unit (ICU) often need supplementary fluids to be given into the bloodstream through a drip in a vein (venous cannula), however too much fluid can be harmful.
- Trial name
- NCT03349749
- Testing
- LiDCOplus haemodynamic monitor
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- NHS Greater Glasgow and Clyde
Hemodynamic Instability
Pulse Pressure Variation Helps to Predict Fluid Responsiveness in Patients Ventilated With Low Tidal Volumes
Objective: To determine the value of pulse pressure variation (ΔRESPPP) to predict fluid responsiveness in patients ventilated with low tidal volumes (VT), and to investigate whether a lower ΔRESPPP cut-off point should be used…
- Trial name
- NCT01569308
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Neurological Diseases or Conditions, Fluid Responsiveness
A Gray Zone Approach to Stroke Volume Variation Derived From NICOM
Optimal fluid management has been considered as crucial part to determine postoperative outcome and organ function. Recently developed, non invasive cardiac output measurement(NICOM, Cheetah Medical, Portland, OR)has enabled…
- Conditions
- Neurological Diseases or Conditions, Fluid Responsiveness, Non Invasive Cardiac Output Monitoring, Gray Zone
- Trial name
- NCT01898975
- Testing
- 500ml fluid loading
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Automated Urine Monitoring, Urine Output
Gravity in Flow: Automating Diuresis
The goal of this randomized clinical trial is to evaluate the accuracy of automated urine output monitoring using the FlowSure system compared to standard manual urine monitoring in hospitalized patients with an indwelling…
- Conditions
- Automated Urine Monitoring, Urine Output, Fluid Balance, Urinary Catheters
- Trial name
- NCT07384325
- Testing
- FlowSure Automated Urine Output Monitor, Manual Urine Monitoring System
- Where
- Netherlands
- Volunteers
- 75 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Surgery, Cardiac Output, Low
Reliability of a New Pulse Contour Technique for Diagnosing an Increase in Stroke Volume During a Fluid Challenge for Hemodynamic Optimization in Patients Scheduled for High-risk Abdominal Surgery: Comparison With Transthoracic Echocardiography: COMPARE Study
The present study aims at assessing the ability of a new pulse contour device for diagnosing a >15% stroke volume (SV) increase during patient hemodynamic optimization by fluid challenge in high risk abdominal surgery.
- Trial name
- COMPARE (NCT04871620)
- Testing
- >15% SV increase during fluid challenge
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Pre-Eclampsia, Severe, Pregnancy
Finger Plethysmography to Predict Fluid Responsiveness in Healthy Pregnancy and Severe Preeclampsia
The goal of this observational study is to determine whether noninvasive finger plethysmographic cardiac output monitoring can help predict fluid responsiveness in pregnant women, including those with preeclampsia with severe…
- Trial name
- NCT07430254
- Testing
- Noninvasive finger plethysmographic cardiac output monitoring, Standard transthoracic echocardiographic assessment
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Stanford University
Goal Directed Therapy, Fluid Therapy
Goal Directed Therapy Versus Standard Care in Lung Resection Surgery (GDT-thorax Study).
The primary aim of this study is to quantify and compare the hemodynamic control of cardiac index in patients who receive either goal-directed therapy or standard hemodynamic management in lung resection surgery
- Trial name
- GDT-thorax (NCT03245372)
- Testing
- Standard care, Goal directed therapy
- Where
- Spain
- Volunteers
- 31 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Cardiac Output, High, Cardiac Output, Low
Pulse Contour Analysis and Tissue Oxymetry in Changing Vascular Tone
The purpose of this study is to compare changes of minimally invasive arterial pulse contour cardiac output with changes of intermittent and continuous thermodilution cardiac output by pulmonary artery catheter in hemodynamic…
- Conditions
- Cardiac Output, High, Cardiac Output, Low, Vasodilation, Vasoconstriction
- Trial name
- NCT00583687
- Testing
- Vigileo TM / Flotrac TM (Minimally invasive cardiac output system consisting of arterial line sensor and cardiac output monitor), Passive leg raising, Volume challenge / Change of vasoactive drugs or inotropics
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Volume Responsiveness
Correlation of Carotid Flow Time and Cardiac Output.
Assessment of common carotid artery flow is more easily done and can be taught more broadly than transthoracic echocardiography, providing a greater number of clinicians a tool to assess volume responsiveness.
- Trial name
- NCT04614701
- Testing
- Carotid Artery Ultrasound Measure
- Where
- Canada
- Sponsor
- St. Boniface Hospital
Hemodynamic Instability, Hypovolemia
Comparison of PPV and LVOT VTI During Passive Leg Raising to Predict Fluid Responsiveness
Hemodynamic instability remains one of the leading causes of morbidity and mortality among critically ill patients in intensive care units. One major contributor to this instability is intravascular fluid deficit.
- Conditions
- Hemodynamic Instability, Hypovolemia, Critical Illness, Pulse Pressure Variation
- Trial name
- NCT07304661
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Izmir Katip Celebi University
Anesthesia
Closed-loop Fluid Administration System: Pilot Study to Evaluate Feasibility
The investigators want to test during anesthesia the feasibility of a closed-loop automated fluid replacement system using cardiac output monitoring as the input value.
- Trial name
- NCT01882075
- Testing
- Open loop, Closed-loop
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hopital Foch
Liver Transplantation (LT), End-stage Liver Disease (ESLD)
Restrictive Fluid Management In Liver Transplantation (REFIL)
The goal of the REFIL-2 study is to evaluate the effectiveness of a low splanchnic blood volume restrictive fluid management strategy (a strategy that involves limiting fluid administration and prioritizing the use of medications…
- Trial name
- REFIL-2 (NCT07695363)
- Testing
- Low splanchnic blood volume restrictive fluid management strategy, Phlebotomy, Optimized cardiac output liberal fluid management strategy
- Where
- 4 sites in Canada
- Volunteers
- 866 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Fluid Overload, Fluid Loss
Atrial Natriuretic Peptide in Assessing Fluid Status
Biomarkers can play a significant role in fluid status assessment intraoperatively.
- Conditions
- Fluid Overload, Fluid Loss, Volume Overload, Cardiac Disease
- Trial name
- NCT05070819
- Testing
- pro-ANP
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Petrovsky National Research Centre of Surgery
Hemodynamic Instability
Uninvasive Cardiac Output Monitoring (USCOM) in Critically Ill Children: Validation and Prediction of Hemodynamic Instability
Hemodynamically unstable ventilated PICU \& PCICU patients, which a decision for commencement in inotropic therapy or fluid bolus has been made, will be recruited.
- Trial name
- NCT02945748
- Where
- Israel
- Volunteers
- 52 people
- Sponsor
- Rabin Medical Center