Clinical trials: Fluid Resuscitation
Kidney Injury
I USE LR in the ED
To study the difference in mortality and major adverse kidney events during and after treatment in the emergency department with intravenous fluids per standard of care at 30 days before and after the system-wide implementation.
- Trial name
- NCT03807648
- Testing
- Data Inclusion
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Fluid Reponsiveness, Fluid Resuscitation
Effect of Colloids Versus Crystalloids on Heart Mechanics: a Double-blind Cross Over Randomized Trial
The debate over whether to use colloid or crystalloid solutions for fluid resuscitationis still ongoing. Colloid solutions consist of large molecules that generally cannot pass through healthy capillary membranes, whereas…
- Conditions
- Fluid Reponsiveness, Fluid Resuscitation, Fluid Therapy
- Trial name
- NCT06900972
- Testing
- Gelafundin
- Where
- Tunisia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Device Related Sepsis
Novel Device for Rapid Fluid Administration
The aim of the study is to determine if a new device is more effective in fluid administration than devices currently used when resuscitating pediatric patients in septic shock.
- Trial name
- NCT03074682
- Testing
- Lifeflow, Push/Pull, Pressure Bag
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Yale University
Cardiac Surgery
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for Cardiac Surgery
After obtaining approval from the Institutional Review Board of our institution, written informed consent is obtained from patients undergoing cardiac surgery are enrolled in this prospective study and randomly allocated into one…
- Trial name
- NCT02757118
- Testing
- Intravenous Crystalloid, Intravenous HES
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Critical Illness
ICU Fluid Utilization Survey in Southeast Asia
The objective of this study is to examine the use of different types of fluids for resuscitation in different phases of fluid management in 3 types of critically ill patients including (1) not bleeding, not septic but need volume…
- Trial name
- Fluid-SEA (NCT06034990)
- Testing
- 10-min online survey
- Where
- Thailand
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Cirrhosis, Liver, Acute-On-Chronic Liver Failure
20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension
Patients with cirrhosis patients have a high incidence of sepsis which can trigger decompensation and may result in prolonged hospital stay and increased mortality.
- Conditions
- Cirrhosis, Liver, Acute-On-Chronic Liver Failure, Shock, Septic, Shock Hypovolemic
- Trial name
- NCT05441878
- Testing
- 20% albumin, Balanced salt solution
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pregnancy Related, Hemorrhage
The Effect of Fluids on Aortic VTI During C-section
Pregnancy is associated with a myriad of physiologic changes, including expansion of blood volume, decrease in oncotic pressure, and increased cardiac output. The obstetric population is associated with intrapartum hemorrhage.
- Conditions
- Pregnancy Related, Hemorrhage, Fluid Overload, Labor Complication
- Trial name
- NCT04330742
- Testing
- lactated ringers
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Critical Care, Fluid Resuscitation
The Fluid Translation of Research Into Practice Study
Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs
- Trial name
- Fluid-TRIPS (NCT02002013)
- Where
- Australia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The George Institute for Global Health, Australia
Change in Serum Chloride Level
Change in Serum Chloride Level After Loading Dose of Sterofundin Solution Compared With Normal Saline Solution
Prospective, crossover, randomized trial to evaluate plasma compositions after loading dose of sterofundin solution given to healthy volunteer in the resuscitation manner compared with normal saline solution.
- Trial name
- NCT02950974
- Testing
- Sterofundin, NSS
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Respiratory Distress
Efficacy and Safety of Gastric Suctioning During Neonatal Resuscitation
The stomach of the newborn baby is often emptied soon after birth to prevent breathing problems (respiratory distress). Babies born with meconium-stained amniotic fluid and those with increased secretions associated with birth by…
- Trial name
- NCT00729989
- Testing
- Gastric suctioning
- Where
- United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Benjamin T. Stevens
Perioperative Hemorrhage, Dilutional Coagulopathy
Impact of Balanced Crystalloid and Colloid Infusion on Haemostasis in Healthy Male Volunteers
The project focuses on perioperative bleeding that requires transfusion of blood products and supplementation of intravascular volume with crystalloids and colloids.
- Trial name
- NCT05148650
- Testing
- Standard laboratory coagulation tests and rotational thromboelastometry measurements
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Resuscitation, Shock
Pediatric Fast Fluid Trial 2
The purpose of this study is to determine which of two commonly used methods of manual pediatric fluid resuscitation (The "Push-Pull Technique" vs.
- Conditions
- Resuscitation, Shock, Fluid Therapy, Pediatrics
- Trial name
- PFFT2 (NCT01774214)
- Testing
- Push-Pull technique, Disconnect-Reconnect Technique
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster Children's Hospital
CABG Surgery
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for CABG Surgery
After obtaining approval from the Institutional Review Board of our institution, written informed consent is obtained from patients undergoing CABG surgery are enrolled in this prospective study and randomly allocated into one of…
- Trial name
- NCT02757027
- Testing
- Intravenous Crystalloid, Intravenous HES
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Septic Shock, Fluid Reponsiveness
This Study Compares Two Noninvasive Dynamic Tools: Lung Ultrasound and Transthoracic Echocardiography Using LVOT VTI. It Aims to Measure the Sensitivity and Specificity of LUS in Guiding Fluid Resuscitation and Early Detection of Fluid Responsiveness and to Prevent Volume Overload
Reliability of the LVOT-VTI versus lung ultrasonography for early detection of fluid intolerance during fluid resuscitation of septic patients.
- Trial name
- lvotvti (NCT07797751)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University