Clinical trials: Fluid and Electrolyte Imbalance
Fluid Overload, Water Electrolyte Imbalance
The Effect of Crystalloids and Colloids on Visceral Blood Flow
Patients often require fluid replacement during and after an operation. This is usually given through veins in the arm using an intravenous cannula and doctors have traditionally used fluid containing sodium chloride (saline).
- Conditions
- Fluid Overload, Water Electrolyte Imbalance, Acid Base Imbalance
- Trial name
- NCT01087853
- Testing
- Crystalloid, Colloid
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Fluid Therapy, Dehydration
Point of Care Ultrasound and Co-loading in Patients With Spinal-induced Hypotension and Cardiac Diseases
In elderly patients with cardiac diseases, changes in cardiovascular physiology diminish cardiovascular reserve and predispose to significant hemodynamic instability after spinal anesthesia; hence, such patients could be at risk…
- Trial name
- NCT06206434
- Testing
- Point of care ultrasonography
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Intravenous Fluids, Fluid and Electrolyte Imbalance
SOFI: A Quality Improvement Project to Standardize Use of Intravenous Fluids in Hospitalized Pediatric Patients
Intravenous fluids (IVF) are used in hospitalized patients to replenish the fluid and electrolyte losses of patients who cannot take adequate hydration by mouth or through their gut.
- Conditions
- Intravenous Fluids, Fluid and Electrolyte Imbalance, ADH Inappropriate
- Trial name
- SOFI (NCT03924674)
- Testing
- Education, clinical decision support tools
- Where
- 89 sites in United States
- Volunteers
- 106 people
- Sponsor
- Seattle Children's Hospital
Dehydration in Children, Dehydration
LifeFlow Fluid Study- Non- Critical Pediatric Patients Having a Trans Abdominal Ultrasound
This is an unblinded, randomized control study examining two fluid delivery modalities for non-critical female patients with a planned transabdominal pelvic ultrasound requiring intravenous fluid boluses.
- Trial name
- NCT03712189
- Testing
- LifeFlow
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Dehydration
Effects of Amino Acid/Electrolyte-based Beverages on Hydration Status
Older adults typically do not drink later in the day to avoid the necessity of interrupting sleep to urinate. Sometimes they also limit ingestion of fluids to avoid the need to urinate when engaged in certain activities such as…
- Trial name
- NCT03559101
- Testing
- Distilled water, Medical Food 1, Medical Food 2
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- W. Larry Kenney
Dehydration
Rehydration Efficiency During Ad-libitum Fluid Intake
It is well established that rehydration with a carbohydrate-electrolyte solution is more effective in comparison to plain water.
- Trial name
- LIV-D2O (NCT06414291)
- Testing
- Plain Water, Liquid IV Hydration Multiplier, Liquid IV Sugar Free
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Hyperkalaemia Requiring Postoperative Dialysis, Metabolic Acidosis
Perioperative Fluid Management in Patients Receiving Cadaveric Renal Transplants
In this study we want to show that the choice of a balanced type fluid solution for the perioperative fluid management of patients receiving cadaveric renal transplantation results in less occurrence of intra- and postoperative…
- Trial name
- NCT01075750
- Where
- Austria
- Volunteers
- 150 people
- Sponsor
- Medical University of Vienna
Hydration, Fluid Retention
Hydration Dynamics and Influence of Beverage Composition
The study examines interactions between fluid availability in the gut and fluid retention in the body. The relative rate of fluid uptake, the expansion of the plasma volume, and percent of fluid retained by the body will be…
- Conditions
- Hydration, Fluid Retention, Dehydration
- Trial name
- NCT05111392
- Testing
- Oral Rehydration Solution 1, Oral Rehydration Solution 2
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Dehydration
Efficacy of a Smart Water Bottle Intervention to Increase Fluid Consumption in College Students
Approximately 60% of males and 40% of females do not meet current fluid intake recommendations, which is associated with adverse health consequences such as obesity, diabetes, and chronic kidney disease.
- Trial name
- NCT06259799
- Testing
- Smart Water Bottle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kennesaw State University
Hypotension, Anomaly; Venous Return
Perioperative Fluid Management in Morbidly Obese Patients
In bariatric surgery functional and feasible non- or mini-invasive modalities for monitoring, and ideal/lean body weight estimates are addressed to meet up individual variability in hydration needs, and to avoid hyperhydration.
- Conditions
- Hypotension, Anomaly; Venous Return, Dehydration
- Trial name
- NCT01873183
- Testing
- Goal directed fluid therapy
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Water-Electrolyte Imbalance, Intensive Care Units
Fluid Overload and Pulmonary Function
Esophageal atresia is a rare but severe malformation, and it requires early surgery. Coloesophagoplasty is surgical repair of the esophageal with an isoperistaltic transverse colon graft.
- Conditions
- Water-Electrolyte Imbalance, Intensive Care Units, Pediatric, Critical Illness
- Trial name
- NCT05129930
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Pirogov Russian National Research Medical University
Hypernatremia, Hyponatremia
Plasma Sodium and Sodium Administration in the ICU
Patients in the Intensive Care Unit often present with low levels of plasma sodium and are therefore often administered high amounts of sodium, both as an additive to intravenous glucose solutions and as a constituent of various…
- Conditions
- Hypernatremia, Hyponatremia, Critical Illness
- Trial name
- NCT06037928
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- University Hospital, Linkoeping
Dehydration, Gastroenteritis
Efficacy Study of IV Fluids Only vs Ondansetron to Treat Dehydration
Dehydration due to vomiting is a common complication of acute gastroenteritis in children. Persistent vomiting following rehydration is a problem in outpatient management using oral rehydration therapy.
- Trial name
- NCT00691275
- Testing
- Ondansetron, Saline
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Dehydration
IV NaCl (Sodium Chloride) 0.9% Vs (Versus) IV NaCl 0.9% + 5% Dextrose in Pediatric ER for Dehydration
Dehydration and refusal to eat and drink are common complaints in the Pediatric ED (Emergency Department). Most of these children have had an unsuccessful trial of oral rehydration in their community service, therefore are…
- Trial name
- NCT02054585
- Testing
- NaCl 0.9%, NaCl 0.9 +5% dextrose
- Where
- Israel
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Stroke, Dehydration
The Fluid Therapy Strategy of the Non-dehydrated Patients With Acute Ischemic Stroke.
The investigators previously found that a blood urea nitrogen/creatinine (BUN/Cr) ratio >15 is an independent predictor of early deterioration after acute ischemic stroke.
- Trial name
- NCT02668848
- Testing
- water
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Chang Gung Memorial Hospital
Hyponatremia, Surgery
Fluid Tonicity and Hyponatraemia Post Surgery
Retrospective audit of adult patients who underwent major surgery in our institution, and biochemical outcomes including hyponatremia, in relation to the maintenance fluid tonicity administered peri-operatively.
- Conditions
- Hyponatremia, Surgery, Fluid and Electrolyte Imbalance
- Trial name
- NCT03840629
- Testing
- No study intervention.
- Volunteers
- 659 people
- Sponsor
- National University Hospital, Singapore
Stroke, Dehydration
BUN/Cr-based Hydration Therapy to Improve Outcomes for Dehydrated Patients With Acute Ischemic Stroke.
The investigators' preliminary findings suggest that providing patients with acute ischemic stroke hydration therapy on the basis of their presenting BUN/Cr ratio may help reduce the occurrence of stroke-in-evolution(SIE) and…
- Trial name
- HYDO (NCT02099383)
- Testing
- normal saline
- Where
- Taiwan
- Volunteers
- 244 people
- Sponsor
- Chang Gung Memorial Hospital
Dehydration, Urinary Infections
GEL-AID: Safe and Effective Hydration for Institutionalized Older Adults
The objective of this clinical trial is to assess whether hydration with gelled water (GEL-AID) can improve fluid intake and reduce cases of dehydration, as well as the incidence of urinary and respiratory infections in…
- Conditions
- Dehydration, Urinary Infections, Respiratory Infections, Daily Fluid Intake
- Trial name
- NCT07381881
- Testing
- GEL-AID, Usual Care
- Where
- Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Dehydration, Retinal Vascular Occlusion
Body-fluid Balance and Drinking Habits in Patients With Retinal Vascular Occlusion
The purpose of this study is to examine the body-fluid balance in patients with retinal vascular occlusion and the influence of drinking habits and hemodilution on the degree of body hydration.
- Trial name
- NCT01939119
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Technische Universität Dresden
Heart Failure, Hyponatremia
The Effect of Fluid Restriction in Congestive Heart Failure Complicated With Hyponatremia
The purpose of this study is to determine the effect of fluid restriction and the neurohormonal mechanisms in the development of hyponatremia in patients with congestive heart failure and hyponatremia.
- Trial name
- Decongest (NCT01748331)
- Testing
- Fluid restriction
- Where
- 2 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Finn Gustafsson