Clinical trials: Fractional Flow Reserve, Myocardial
Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI
FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease
To compare FFR guided complete revascularization during the index procedure with usual care in non-STEMI patients with multivessel disease.
- Conditions
- Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI, Fractional Flow Reserve, Myocardial, Myocardial Revascularization
- Trial name
- SLIM (NCT03562572)
- Testing
- Ischemia driven revascularization, Usual care group
- Where
- 9 sites in Czechia, Hungary and 1 more
- Volunteers
- 476 people
- Sponsor
- Zuyderland Medisch Centrum
Tomography, Optical Coherence, Fractional Flow Reserve, Myocardial
OCT-based Machine Learning FFR for Predicting Post-PCI FFR
This study aims to compare the diagnostic accuracy of the fractional flow reserve (FFR) model derived by machine learning based on optical coherence tomography (OCT) exam after coronary artery stent implantation with the…
- Trial name
- NCT06341361
- Testing
- OCT-based machine learning FFR
- Volunteers
- 82 people
- Sponsor
- Yonsei University
Coronary Angiography, Fractional Flow Reserve, Myocardial
Fractional Flow Reserve Derived From CT Related Treatment
This study is a retrospective, single-center study.This experiment aims to explore the influence of CT-FFR as a relevant for revascularization on the prognosis of patients with coronary heart disease, assessing concurrent on…
- Conditions
- Coronary Angiography, Fractional Flow Reserve, Myocardial, Coronary Artery Disease
- Trial name
- NCT05319119
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Coronary Artery Disease, Myocardial Ischemia
Evaluation of Accuracy of CFD-based RuiXin-FFR by Comparing With Pressure-wire-based FFR
Coronary Artery Disease (CAD) is the top killer nowadays. Pressure-wire-based Fractional Flow Reserve (FFR) is the gold standard for measuring ischemia in coronary arteries.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Myocardial Fractional Flow Reserve
- Trial name
- NCT04731285
- Testing
- Pressure wire fractional flow reserve, CFD-based RuiXin-FFR
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Beijing Anzhen Hospital
Fractional Flow Reserve, Absolute Flow Measurement
Myocardial Mass Determination by FFRct and Absolute Coronary Blood Flow
The background for performing the present study is to compare the mass calculations by CT scanning and by invasive absolute blood flow measurements and thereby corroborating both methods.
- Conditions
- Fractional Flow Reserve, Absolute Flow Measurement, FFR-CT, Myocardial Mass
- Trial name
- MyoMass (NCT03393871)
- Testing
- absolute blood flow measurement
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Fractional Flow Reserve
DSE vs Invasive FFR vs CT-FFR
Data are limited regarding the optimal treatment of the non-culprit lesions (NCL) after myocardial infarction (MI). The NON-CULPRIT study is a prospective cohort study with a primary aim to compare invasive fractional flow…
- Trial name
- NON-CULPRIT (NCT03988881)
- Testing
- Revascularization
- Where
- 2 sites in Hungary
- Volunteers
- 100 people
- Sponsor
- Semmelweis University Heart and Vascular Center
Fractional Flow Reserve, Myocardial, Coronary Artery Disease
Performance of a New REsting Pressure Index During Invasive Angiography Compared To Adenosine Hyperemic FFR
To test the feasibility and diagnostic accuracy of a new automated pressure derived resting index (Pd/Pamin), using FFR as gold standard, in de novo coronary lesions in which invasive physiological evaluation is warranted.
- Trial name
- PREDICT (NCT03237169)
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 100 people
- Sponsor
- Centro Hospitalar Lisboa Ocidental
Fractional Flow Reserve, Myocardial, Coronary Artery Disease
Diagnostic Agreement of iFR and QFR.
A Prospective, observational, single center diagnostic study to investigate the the diagnostic agreement between QFR and the pressure wire-based iFR in a real world setting.
- Trial name
- DETECTISCHEMIA (NCT03420131)
- Testing
- QFR and iFR
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Contilia Clinical Research Institute
Coronary Disease, Echocardiography
Meta-Analysis of Stress Myocardial Perfusion Imaging
Background: Detection of coronary artery disease (CAD) is important due to its high prevalence and its medical and economic implications.
- Conditions
- Coronary Disease, Echocardiography, Fractional Flow Reserve, Myocardial, Hemodynamics
- Trial name
- NCT03180060
- Where
- Mexico
- Volunteers
- 23,051 people
- Sponsor
- American British Cowdray Medical Center
Fractional Flow Reserve, Myocardial
Safety of Negative FrActional Flow Reserve in Patients With ChallEnging Lesions
Fractional Flow Reserve (FFR) has recently emerged and has been largely validated as a safe and efficacious way of ischemia testing for patients with stable angina.
- Trial name
- FACE (NCT02590926)
- Testing
- Fractional Flow Reserve, Myocardial
- Where
- Italy
- Volunteers
- 285 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Fractional Flow Reserve, ST-segment Elevation Myocardial Infarction
Fractional Flow Reserve Versus Angiography for Guiding Selective Percutaneous Coronary Intervention in ST-segment Elevation Myocardial Infarction
To assess the outcomes of patients with ST-segment elevation myocardial infarction (STEMI) assigned to fractional flow reserve (FFR) and angiography-guided selective percutaneous coronary intervention (PCI).
- Conditions
- Fractional Flow Reserve, ST-segment Elevation Myocardial Infarction, Percutaneous Coronary Intervention
- Trial name
- NCT02670005
- Volunteers
- 600 people
- Sponsor
- Nanjing Medical University
Perfusion Imaging, MRI
MRI Perfusion Imaging at 3Tx Compared to Invasive FFR Measurements
Coronary artery disease (CAD) has a great significance concerning prevalence and mortality in the western world. It is usually diagnosed by catheterization and coronary arteries are visually assessed by the examiner.
- Conditions
- Perfusion Imaging, MRI, Myocardial Fractional Flow Reserve, Myocardial Ischemia
- Trial name
- Vision MRT (NCT01277055)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Heart Center Bogenhausen
Coronary Angiography, Drug-eluting Stents
Proper Fractional Flow Reserve Criteria for Intermediate Lesions in the Era of Drug-eluting Stent
Angiographic evaluation for intermediate lesions is not always accurate. Fractional flow reserve-guided deferral strategy for these lesions showed the same event rate as routine intervention strategy.
- Conditions
- Coronary Angiography, Drug-eluting Stents, Fractional Flow Reserve, Myocardial
- Trial name
- DEFER-DES (NCT00592228)
- Testing
- Cypher, Taxus or Endeavor
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Seoul National University Hospital