Clinical trials: Frozen Embryos
Vaginal Flora Imbalance
Vaginal Microbiome and IVF Pregnancy Outcome
The aim of this prospective, observational study is to investigate the prevalence of vaginal dysbiosis among women undergoing IVF procedures in the US.
- Trial name
- NCT05150639
- Testing
- IVF
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Infertility of Uterine Origin, Implantation Failure
International Non-selection Study for ERA® Test in Patients With Previous Implantation Failures
Women´s period comprises different hormonal stages, being one of them the stage for maximum receptivity and proper embryo implantation.
- Trial name
- NCT06097559
- Testing
- Endometrial fluid and biopsy collection
- Where
- 8 sites in Argentina, Panama and 2 more
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Igenomix
IVF
Immediate Versus Postponed Freeze-all Embryo Transfer in Hyperresponders
This is a multicenter, randomised controlled trial. The investigators plan to randomise 836 participants to the immediate FET or the postponed FET from the day of oocyte retrieval to the last day of that menstrual cycle in a 1:1…
- Trial name
- NCT05483270
- Testing
- the timing of embryo transfer in freeze-all cycles
- Where
- China
- Volunteers
- 845 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility, Endometriosis
Platelet Rich Plasma Uterine Infusion
Platelet Rich Plasma (PRP), a rich source of important growth factors, has been shown to significantly affect the body's ability to heal and regenerate tissues.
- Trial name
- NCT06621342
- Testing
- PRP Experimental
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Human Embryo Cryopreservation
Comparison Between Three Freezing Protocols to Preserve Human Embryos
This randomized study compares three different freezing methods to store human in vitro fertilization (IVF) embryos: vitrification with two commercial kits or slow freezing.
- Trial name
- NCT00910390
- Testing
- Slow freezing, VIT-Irvine, Vit-Vitrolife
- Where
- Belgium
- Volunteers
- 584 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Pregnancy Related, Pre-Eclampsia
Natural Versus Programmed Frozen Embryo Transfer (NatPro)
NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed…
- Trial name
- NatPro (NCT04551807)
- Testing
- Modified natural cycle, Programmed cycle
- Where
- 15 sites in United States
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- JHSPH Center for Clinical Trials
Infertility, Female
Success Rate Natural Cycles Versus Modified Natural Cycles in Frozen Embryos
There has been a recent significant increase in the frozen embryo replacement (FER) cycles due to freeze-all cycles to decrease the risk of ovarian hyperstimulation syndrome.
- Trial name
- NCT03798886
- Testing
- natural cycle, modified natural cycle, embryo transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Fertility Issues
Correlation of Urinary and Serum Hormone Levels in Natural Cycle Frozen Embryo Transfer Cycles
To evaluate whether the measurement of urinary estrone glucuronide and luteinizing hormone (LH) concentrations with an at-home device is correlated with serum hormone levels within a natural cycle frozen embryo transfer protocol.
- Trial name
- MIRA (NCT06410170)
- Testing
- MIRA Device
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
GnRH Agonist
Effect of GnRH Agonist in FET
To evaluate the impact of single dose GnRH agonist administration as luteal phase support on pregnancy outcomes in frozen ICSI cycle
- Trial name
- gnrh agonist (NCT07653282)
- Testing
- GnRH agonist
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University
Infertility
The Effects of Two Endometrium Preparation Protocols in Frozen-thawed Embryo Transfer in Women With Irregular Cycles
There are two main cycle regimens used for endometrial preparation for frozen embryo transfer （FET) in women with irregular cycles: hormone replacement therapy cycles (HRT) in which the endometrium is artificially prepared by…
- Trial name
- NCT01780610
- Testing
- Letrozole and human chorionic gonadotrophin, estradiol and progesterone
- Where
- China
- Volunteers
- 670 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Infertility
Oocyte Cryopreservation: Slow Cooling Versus Vitrification Techniques on Oocyte Survival
Oocyte cryopreservation has been studied for many years without much success in refining a method that has consistent, reliable results in producing viable embryos and clinical pregnancies.
- Trial name
- NCT00602966
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- UConn Health
Luteal Phase Support
Two Different Types of Luteal Phase Support in Natural Cycle Frozen Embryo Transfer and Its Effect on Pregnancy Rates
The aim of the study is to compare the pregnancy rate between women treated with Gonadotropin Releasing Hormone (GnRH) agonist together with Human Chorionic Gonadotropin (HCG) and standard luteal support with progesterone…
- Trial name
- NCT05838105
- Testing
- GnRH agonist, hCG, Progesterone 100Mg Vag Tab
- Where
- Israel
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Assisted Reproductive Technology
Progesterone Supplementation on Women Having Low Progesterone Levels on Transfer Day
The main objective of this study is to compare clinical pregnancy rates between two groups of women who have progesterone levels below 10 ng/mL on the day of frozen embryo transfer: group 1 (vaginal micronized progesterone…
- Trial name
- NCT04897269
- Testing
- Progesterone supplementation
- Where
- Vietnam
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital
Infertility, Pregnancy Related
The Impact of Vaginal Intercourse on Pregnancy Rates After Frozen Embryo Transfer
This study aims to evaluate whether allowing unprotected vaginal intercourse 24 hours after frozen embryo transfer will result in higher ongoing clinical pregnancy rates in comparison to having participants abstain from…
- Conditions
- Infertility, Pregnancy Related, IVF
- Trial name
- NCT03974295
- Testing
- Vaginal unprotected intercourse
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Thin Endometrium
a-PRP Intrauterine Instillation in Women With Thin Endometrium
This study sought to compare the endometrial thickness among infertile women with a history of thin endometrium together with previous cancellation from IVF/ICSI inspection of intrauterine instillation of autologous-PRP or no…
- Trial name
- PRP(a-PRP) (NCT06234540)
- Testing
- PRP, Standard treatment
- Where
- Thailand
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Infertility
Vitrification and Slow Freezing for Cryopreservation of Blastocyst
Improvement in the treatment of infertility by Assisted Reproductive Techniques (ART) allows single embryo transfer to be applied without compromising pregnancy rates after the first in vitro fertilization (IVF) or Intra…
- Trial name
- NCT02068924
- Testing
- Slow freezing versus vitrification
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Infertility Due to Nonimplantation, Infertility
Progesterone Supplementation in Frozen Embryo Transfer Cycles
Recurrent implantation failure (RIF) occurs after women undergo in vitro fertilization and have multiple embryos transferred but no resulting pregnancies.
- Trial name
- NCT03504345
- Testing
- Prometrium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Infertility, Embryo Transfer
Mucus Removal Before Embryo Transfer
Despite these revolutionary changes in the laboratory, little has changed with the process of embryo transfer (ET). A study to prospectively evaluate the role of cervical mucus removal prior to embryo transfer on pregnancy rates…
- Trial name
- MUCRET (NCT03292770)
- Testing
- Flushing Catheter
- Where
- Spain
- Volunteers
- 1,118 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Infertility
The Effect of Baseline Bilateral Uterine Artery Doppler Velocimetry on Obstetric Outcomes in HRT-FET Cycles
Researchers aim to determine how baseline (pre-conceptional) uterine perfusion characteristics affect implantation rates and obstetric complications in women who underwent high-quality blastocyst transfer.
- Trial name
- NCT05526014
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Infertility, Infertility, Female
The Outcome of Two Protocols Used to Prepare Endometrium for Frozen Embryo Transfer
This is a RCT to test the outcome of two protocols used for preparation of the endometrium for frozen blastocyst embryo transfer
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- NCT04507022
- Testing
- Estradiol Valerate, Progesterone, Aromatase inhibitor
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Rahem Fertility Center