Clinical trials: Frozen Embryos
IVF
Effect of HCG on Endometrial Preparation in Frozen Embryo Transfer
Intramuscular injection of HCG to prepare endometrium for frozen embryo transfer
- Trial name
- NCT06577181
- Testing
- hCG + estradiol, Observation arm
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Infertility, Female, Reproductive Techniques, Assisted
SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques
The goal of this clinical trial is to learn whether two different methods of helping eggs and sperm join-intracytoplasmic sperm injection (ICSI) and conventional in vitro fertilization (IVF)-lead to better embryo development when…
- Conditions
- Infertility, Female, Reproductive Techniques, Assisted, Fertilization in Vitro
- Trial name
- SISTER (NCT07175571)
- Testing
- Intracytoplasmic Sperm Injection (ICSI), Conventional Insemination (IVF)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility
Assesment of Embryo Viability and Re-expansion After Thawing in Blastocyst Stage Embryos
In this prospective study, the possible effects of embryo viability and degree of blastocele re-expansion on pregnancy outcomes before vitrified/thawed blastocyst transfer will be evaluated.
- Trial name
- NCT05474833
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Frozen Embryo Transfer
Assessing the Convenience of Natural Proliferative Phase Frozen Embryo Transfer
This study will assess the convenience of the natural proliferative phase frozen embryo transfer (NPP-FET) in terms of number of number of appointments needed before cycle scheduling.
- Trial name
- NCT06307184
- Testing
- Natural proliferative phase frozen embryo transfer
- Where
- Portugal
- Volunteers
- 530 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility Female, Frozen Embryo Transfer (FET)
FET-LET-2x2: Clinical Pregnancy Rates After Frozen Embryo Transfer in Natural and Modified Natural Cycles
The goal of this clinical trial is to learn whether different natural approaches to preparing the uterus for frozen embryo transfer (FET) can improve pregnancy success in women undergoing in vitro fertilization (IVF) treatment.
- Trial name
- FET-LET-2x2 (NCT07425990)
- Testing
- Letrozole (Aromatase Inhibitors), Choriogonadotropin alpha (r-hCG), Progesterone
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- University of Novi Sad
Fertility Agents, Female
hCG Supplementation in Frozen-Thawed Embryo Transfer Cycle
The implantation rate after frozen-thawed embryo transfer cycles depends mostly on the receptivity of the endometrium and the embryo quality.The effects of human chorionic gonadotropins (hCG) on the endometrium have been…
- Trial name
- NCT00398229
- Testing
- s.c. human chorionic gonadotropin (Ovitrelle)
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Infertility
Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Frozen Embryo Transfer on Cycle Outcomes
The present study is designed as a pilot study with 150 patients in each group. Data collection form will be filled by the researcher who does not know the type of intervention in each group.
- Trial name
- NCT02355925
- Testing
- intrauterine injection of uhCG, control
- Where
- Iran
- Volunteers
- 180 people
- Sponsor
- Royan Institute
Infertility
Prolutex in Frozen Embryo Transfer Cycles At the Blastocyst Stage (PROGEX)
The objective of this proof of concept clinical trial is to evaluate the impact of two different progesterone treatments for endometrial preparation (25 mg/twice-a-day, subcutaneous injection, and 200 mg/three times a day…
- Trial name
- PROGEX (NCT03701490)
- Testing
- Progesterone subcutaneous, Progesterone Vaginal Product
- Where
- 3 sites in Spain
- Volunteers
- 213 people
- Sponsor
- IBSA Institut Biochimique SA
Infertility, Female
Personalized FET in RIF Patients With Displaced Dating
The endometrium becomes receptive as a result of a series of timed hormonal events during the menstrual cycle. The exposure of the endometrium to progesterone after ovulation initiates morphological and functional alterations…
- Trial name
- NCT03910582
- Testing
- personalized frozen-thawed embryo transfer, routine frozen-thawed embryo transfer
- Volunteers
- 117 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Letrozole, Infertility, Female
The Effectiveness of the Letrozole-induced Endometrial Preparation Protocol in Frozen-thawed Embryo Transfer (FET)
The goal of this single center, non-blinded, randomized controlled clinical trial to comparison of pregnancy outcomes and perinatal outcomes in patients undergoing IVF treatment (including ICSI) with FET with letrozole-induce…
- Trial name
- NCT06006091
- Testing
- Letrozole
- Where
- China
- Volunteers
- 858 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Reproductive Issues
Impact of Serum Progesterone Levels on Embryo Transfer Day on Clinical Pregnancy
Hypotheses: We hypothesize that serum progesterone levels on the day of embryo transfer in HRT-FET cycles are positively associated with clinical pregnancy rates.
- Trial name
- NCT07388797
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Chinese University of Hong Kong
Infertility
GnRH Agonist as Luteal Support in FET Cycles
Back ground: A single dose of GnRH analogue in the luteal phase is reported to improve the outcome of IVF/ICSI treatments but the effect in FET cycles has not been reported.
- Trial name
- NCT02620124
- Testing
- Natural cycle: Triptorelin acetate 0.1 mg, Hormone replacement cycle and triptorelin acetate 0.1 mg
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Ovarian Hyperstimulation Syndrome
Ovarian Hyperstimulation Syndrome (OHSS) Prevention With Agonist
The aim of the study is to explore the concept of GnRH-agonist triggering in combination with elective cryopreservation of all 2PN oocytes at larger scale in a pragmatic clinical setting.
- Trial name
- NCT00835523
- Where
- 10 sites in Germany
- Volunteers
- 51 people
- Sponsor
- University Hospital Schleswig-Holstein
PCOS, IVM
Fresh Versus Freeze-only After CAPA IVM on PCOS Patients
IVM (in vitro maturation) has been proved to be a more friendly treatment protocol for PCOS (polycystic ovary syndrome) patients compared with conventional controlled ovarian stimulation, with less complications (especially…
- Conditions
- PCOS, IVM, Embryo Transfer
- Trial name
- NCT04297553
- Testing
- CAPA-Fresh, CAPA-Freeze-only
- Where
- Vietnam
- Volunteers
- 40 people
- Sponsor
- Mỹ Đức Hospital
Frozen Embryo Pregnancy Rate
Progesterone Support of FET
There have been two very common forms of progesterone administration that have been used during ovulation induction, in vitro fertilization (IVF) and embryo transfers.
- Trial name
- FETProg (NCT01058382)
- Testing
- Progesterone Vaginal Suppositories, Intramuscular Progesterone-in-Oil
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Charles Coddington
IVF
Comparative Study Between Fresh and Frozen Embryo Transfer in PCOS Patients Undergoing IVF Treatment
The objective of our study is to compare in vitro fertilization (IVF) outcomes between fresh embryo transfer (ET) and frozen-thawed ET in women with polycystic ovary syndrome (PCOS).
- Trial name
- NCT05167838
- Testing
- fresh embryo transfer, Frozen embryo transfer
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility
Graduated Embryo Score (GES) in the Fresh Cycle Predicts Outcome From Frozen Embryo Transfer
Evaluation of embryo quality in the fresh cycle as a predictor of outcome from frozen embryo transfer.
- Trial name
- GES/FET (NCT00694434)
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Sher Institute for Reproductive Medicine, Las Vegas
In Vitro Fertilization
Replacement of Fresh Embryo Transfers (ETs) by Frozen Embryo Transfers (FETs) Using Vitrification
Cryopreservation of all embryos and transferring them subsequently in assisted reproductive technology (ART) cycles to improve outcome.
- Trial name
- NCT00823121
- Testing
- freezing embryos by vitrification, fresh embryo transfers, buserelin
- Where
- Iran
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yazd Research & Clinical Center for Infertility
Infertility
Natural Versus HRT Cycles in Frozen Embryo Replacement Treatment
Frozen Embryo Replacement (FER)is a fertility treatment by which stored embryos from a fresh IVF treatment cycle are thawed and transferred into the uterus.
- Trial name
- NCT00843570
- Testing
- Nafarelin acetate, Oestradiol Valerate, Progesterone
- Where
- 2 sites in United Kingdom
- Volunteers
- 159 people
- Sponsor
- University of Oxford
Vaginal Dysbiosis
Effect of FB301 on Vaginal Bacterial Profile in Women With Asymptomatic Vaginal Dysbiosis Undergoing a Mock Frozen Embryo Transfer Cycle
The goal of this clinical trial is to evaluate FB301 during a mock frozen embryo transfer (FET) cycle in pre-menopausal women aged 18 to 45 years with a prior failed FET and a defined vaginal bacterial imbalance (dysbiosis).
- Trial name
- NCT07453069
- Testing
- FB-301, Chlorhexidine (0.5%) Vaginal Cleanse
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Freya Biosciences ApS