Clinical trials: Functional Capacity
Mitochondrial Diseases
Impact of Statin Therapy on Muscle Mitochondrial Function and Aerobic Capacity
The purpose of this study is to test how different doses of a statin, Lipitor, affect muscle health and function, and cardiovascular fitness.
- Trial name
- NCT03351998
- Testing
- Lipitor 20Mg Tablet, Lipitor 80Mg Tablet
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Prediabetic State, Diabetes Mellitus, Type 2
Cardiorespiratory Fitness in Prediabetic,Type 2 Diabetic and Healthy Individuals
The aim of this study to investigate and compare cardiorespiratory fitness (CRF) parameters of prediabetic, type 2 diabetic and healthy individuals.
- Conditions
- Prediabetic State, Diabetes Mellitus, Type 2, Cardiorespiratory Fitness, Inflammation
- Trial name
- NCT03823664
- Testing
- Cardiorespiratory Fitness
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Aging, Healthy
Healthy Aging Through Dietary Intervention
To test the impact of flavanol supplementation of cardiac and vascular function and subsequently on exercise capacity in elderly individuals
- Trial name
- NCT05782309
- Testing
- Flavanol
- Where
- Germany
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Respiratory Function
Effect of a Respiratory Training Program on Woodwind and Brass Players
This project will study the effect of a respiratory training program on woodwind and brass players, using an inspiratory muscle training equipment.
- Trial name
- NCT06175286
- Testing
- POWERBreath Plus Medium Resistance training device
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Heart Failure, Nursing Caries
Physical Activity Program on Clinical Output in Heart Failure
Background: This study was carried out to determine the effect of physical activity program applied to individuals with heart failure on quality of life, functional capacity and mortality risk level.
- Trial name
- Heartfailu (NCT05349786)
- Testing
- Physical activity program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Healthy
Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength, Muscle Oxygen Saturation, and Functional Capacity
Respiratory muscle training represents an effective method increasingly utilized in both sports and healthcare domains, employing various devices, among which threshold devices are prominent.
- Trial name
- NCT06266013
- Testing
- inspiratory muscle training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Parkinson Disease
Respiratory Functions in Parkinson's Disease
The aim is to examine respiratory functions, inspiratory muscle strength, respiratory function, physical fitness and aerobic capacity in Parkinson's disease patients.
- Trial name
- NCT07010783
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stem Cell Transplantation
Physical Impairments in Allogeneic-HSCT
Pulmonary functions, exercise capacity and muscle strength deteriorate in survived hematopoietic stem cell transplantation (HSCT) recipients due to toxic effects of chemotherapy, radiotherapy, conditioning regimens and/or…
- Trial name
- NCT03448627
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Gazi University
Aerobic Performance, Respiratory Function
Integrating Halotherapy Into Preseason Training Improves Respiratory and Aerobic Performance in Elite Female Soccer Players
This randomized controlled trial aimed to investigate the effects of a 12-week halotherapy intervention on respiratory muscle strength, pulmonary function, aerobic capacity, and intermittent running performance in elite female…
- Conditions
- Aerobic Performance, Respiratory Function, Athletic Performance, Respiratory Muscle Strength
- Trial name
- NCT07406386
- Testing
- Halotherapy Group, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
COPD
Comparing Pressure Based and Dilution Based Total Lung Capacity Measurements in COPD Patients for Lung Function Diagnostics
Total Lung Capacity (TLC) of the lungs can be determined using a pressure based method (i.e. by body plethysmography) or it can be determined using a dilution based method (i.e.
- Trial name
- NCT04531293
- Testing
- Respiratory Analysis System
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- ndd Medizintechnik AG
Heart Failure, Type 2 Diabetes
Effects of Dark Chocolate on Exercise Capacity, and Mitochondrial Structure and Function
The major goal of this study is to characterize the ability of dark chocolate enriched in epicatechin (a component of dark chocolate) to improve the structural and functional features of mitochondria in two groups 1.
- Trial name
- NCT01671514
- Testing
- Epicatechin-enriched dark chocolate, Low-epicatechin dark chocolate
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Athlete Heart
Myocardial Mechanics in Athlete's Heart
Echocardiographic assessment of the endurance athletes' heart remains challenging due to a phenotypic overlap between reactive physiological adaptation and pathological remodelling.
- Trial name
- NCT05543525
- Testing
- Echocardiography, Cardiopulmonary exercise testing
- Where
- France
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Acellular Dermal Matrix, Bone Grafting
Evaluating the Barrier Function, Regenerative Capacity, and Soft Tissue Outcomes of Acellular Dermal Matrix
This investigator-initiated study will compare ADM and resorbable cross-linked collagen membrane barriers for guided bone regeneration at atrophic lateral ridge augmentation sites.
- Conditions
- Acellular Dermal Matrix, Bone Grafting, Soft Tissue Grafting
- Trial name
- NCT07613047
- Testing
- Guided Bone Regeneration with ADM (AlloDerm) as a barrier, Guided Bone Regeneration with Resorbable Crosslinked Collagen Matrix (Mem-Lok) as a barrier
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Post COVID-19
Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
When the literature search is conducted, it is seen that there are many studies examining the effects of COVID-19 disease on individuals in various disease groups (MS, stroke, Parkinson, COPD, asthma, etc.) and age groups (adult…
- Trial name
- PEPICov (NCT05282043)
- Testing
- Evaluation of Pulmonary and Extrapulmonary Impacts of COVID-19 on Young Adults
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
TLC in Patients With and Without Respiratory System Disease
Measurement and Evaluation of Total Lung Capacity (TLC) in the Field of Pulmonary Functional Testing (PFT)
A comparative study to test the efficacy of a novel device - the MiniBoxPFT, in measuring TLC (total lung capacity) compared to TLC measured by standard body plethysmography using the ZAN 500.
- Trial name
- NCT01952431
- Testing
- Total Lung Capacity (TLC) testing
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- PulmOne Advanced Medical Devices, Ltd.
Early Mobilization, Physiotherapy
Rehabilitation of Patients From the ICU to the Post-hospital Phase
Introduction: Advances in knowledge have contributed to the increase in the number of patients who survive prolonged hospitalization in an Intensive Care Unit (ICU), and, among them, critically ill patients who develop acute…
- Conditions
- Early Mobilization, Physiotherapy, Rehabilitation
- Trial name
- NCT06405529
- Testing
- Early and intensive mobilization protocol at the ICU and Rehabilitation post-hospital discharge
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy, Healthy Adult
Assessment of Lung Function (Lufu) at Sea Level LA vs. High Altitude HA in Healthy Individuals
To study the effect of a re-ascent to high altitude (Quito Ecuador: 2850m) after a one-week stay at sea level (after prior descent from 2850m) on lung function and pulmonary resistance/reactance in healthy individuals, who live…
- Conditions
- Healthy, Healthy Adult, High Altitude Effects, High Altitude
- Trial name
- NCT07804537
- Testing
- Re-ascent from sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Apnea, Hypoxia
Effects of Automated Adjustment of Inspired Oxygen With Combined Adaptive Mechanical Backup Ventilation as Compared to Automated Oxygen Adjustment Alone in Preterm Infants With Intermittent Hypoxemic Events During Non-invasive Ventilatory Support
In this 2-phase cross-over study the investigators test the hypothesis that automated adjustment of the inspired oxygen with the combined use of synchronized noninvasive SpO2-sensitive and apnea-sensitive backup-ventilation…
- Trial name
- NCT02774408
- Testing
- Saturation sensitive backup ventilation
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Respiration Disorder, Posture
Thoracic Mobility, Posture, Functional Capacity, and Respiratory Rate in Children Playing Wind Instruments
The aim of this study is to evaluate thoracic mobility, posture, functional capacity, and respiratory rate in children aged 8-14 years who play wind instruments and to compare these findings with those of their peers who do not…
- Conditions
- Respiration Disorder, Posture, Functional Capacity, Music
- Trial name
- WIND-KIDS (NCT07477535)
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Mixed Reality, Asymptomatic
Validity and Reliability of a Mixed Reality-Based 6-Minute Walk Test
The 6-Minute Walk Test (6MWT) is a widely used field test for assessing functional exercise capacity, walking endurance, and submaximal performance related to activities of daily living.
- Trial name
- NCT07601009
- Testing
- Mixed Reality-Based 6-Minute Walk Test Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Selcuk University