Clinical trials: Functional Cognitive Disorder
Cognitive Dysfunction
Probing Cortical Excitability and Cognitive Function With TMS
The overarching purpose of this study is to develop a technique that is capable of identifying neurophysiological biomarkers sensitive enough to detect preclinical dementia by integrating Transcranial Magnetic Stimulation (TMS)…
- Trial name
- NCT03652012
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Multiple Sclerosis
Video Games Therapy on Balance and Cognitive Functions in Mild to Moderate Impaired Multiple Sclerosis Patients.
Multiple Sclerosis (MS) is often characterized by the presence of balance and cognitive impairments. Cognitive functions play a key role in balance control.
- Trial name
- NCT03353974
- Testing
- Video game therapy, Balance platform therapy
- Where
- 2 sites in Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Obesity, Childhood, Overweight, Childhood
Sleep and Stigma: Novel Moderators in the Relationship Between Weight Status and Cognitive Function
The investigators aim to assess the relationship between overweight/obesity and decreased cognitive function in adolescents. While this relationship has been seen in past literature, the causal mechanisms are still unclear.
- Trial name
- NCT04346433
- Testing
- Restricted Sleep, Adequate Sleep
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Menopause, Cognitive Deficits, Mild
Effect of Time-restricted Eating on Cognitive Function and Other Biopsychosocial Factors in Menopausal Women Undertaking a 12-week Exercise Programme
The goal of this quasi-experimental study is to test effect of time-restricted eating on cognitive function and other biopsychosocial factors in menopausal women undertaking a 12-week exercise programme.
- Trial name
- NCT06138015
- Testing
- Exercise and Time-Restricted Eating, Exercise only
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Phobias
fMRI Study Examining Effects of D-cycloserine in Specific Phobia
The research team hopes to use brain imaging and mental testing to learn more about specific phobias and the treatment of phobia.
- Trial name
- NCT00591825
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Spinal Cord Injury
A Longitudinal Examination of Aging With a Spinal Cord Injury: Cardiovascular, Cerebrovascular and Cognitive Consequences
The general population is aging, today 12% of the United States population is older than 65 and it is estimated that by 2020 the number of people in the United States older than 65 will outnumber children younger than 5.
- Trial name
- NCT03023163
- Testing
- Longitudinal
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
OCD
Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder
This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.
- Trial name
- 3TOC (NCT05843604)
- Testing
- Functional MRI
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Henri Laborit
Cognitive Change, Diet, Healthy
Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
- Trial name
- NCT06605898
- Testing
- MIND Diet, Control Diet
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Aphasia, Autism
Transcranial Direct Current Stimulation (tDCS) and Cognitive Processing
This research is being done to determine whether transcranial direct current stimulation (tDCS) can improve certain mental abilities.
- Conditions
- Aphasia, Autism, Schizophrenia
- Trial name
- NCT01602263
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Frailty
Mesenchymal Stem Cells for Age-Related Frailty
Frailty is a health state related to the aging process in which multiple body systems gradually lose their built-in reserves. It is a medical condition of reduced function in older adults which is associated with increased risks…
- Trial name
- MESCAFY (NCT05284604)
- Testing
- Mesenchymal Stem Cells (MSCs)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Aging, Mild Cognitive Impairment
A Study of Characterizing Cognitive Decline and Functional Cardiac Senescence in Healthy Korean Volunteers
Although aging process appears to be generally characterized, investigators have been paid much attention to the specific target molecules, which leads to discover the clinical markers of the senescence.
- Conditions
- Aging, Mild Cognitive Impairment, Angina Pectoris
- Trial name
- NCT01590706
- Where
- South Korea
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Korea Institute of Oriental Medicine
Schizophrenia, Psychosis
Cognitive Remediation in Schizophrenia
The aim of this project is to undertake a randomized placebo controlled trial of cognitive remediation therapy (CRT) that focuses on working memory training in a sample of community based patients with chronic schizophrenia or…
- Trial name
- NCT01903707
- Testing
- Cognitive Remediation Therapy
- Where
- Ireland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Thyroid, Carotid Doppler
Effect of Head Position During Thyroidectomy on Postoperative Cognitive Functions
The aim of our study is to observe the effect of head-neck position of patients scheduled for thyroidectomy, on carotid artery blood flow, regional cerebral oxygen saturation measured using near-infrared spectroscopy technology…
- Conditions
- Thyroid, Carotid Doppler, Cerebral Perfusion
- Trial name
- NCT04830293
- Testing
- Carotis Doppler Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Drug Abuse, Nicotine Dependence
Cognitive Task Development and Implementation for Functional MRI Studies
Background: Drugs of abuse have effects on mood, behavior, thinking, and decision making that may encourage people to continue using them and make it difficult for them to stop.
- Trial name
- NCT01036685
- Where
- United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Vestibular Dysfunction, Dizziness
Vestibular Balance-Cognition Dual-Task Digital System: Development of a Smart Rehabilitation Platform for the Elderly and Prediction of Balance Function Risks
This study is being done to better understand how vestibular problems and thinking abilities (such as attention and mental flexibility) are related in older adults, and how doing a balance task and a thinking task at the same…
- Conditions
- Vestibular Dysfunction, Dizziness, Falls (Accidents) in Old Age, Balance Assessment
- Trial name
- NCT07735078
- Testing
- Instrumented balance and gait assessment using wearable inertial sensors, Questionnaires and paper-based cognitive tests
- Where
- Taiwan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Obesity, Childhood, Obesity, Adolescent
Reading Ability in Childhood Obesity
There is some evidence about the negative impact of overweight and obesity on reading ability, with negative consequences on quality of life and school success.
- Trial name
- Lettura_evOB (NCT06295406)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Cognitive Deficits, Cognitive Ability, General
Childhood Anesthesia and Cognitive Function
The purpose of this study is to determine whether pediatric anesthesia is associated with long-term hippocampal dysfunction
- Trial name
- UCSF-Anes-01 (NCT01359215)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obstructive Sleep Apnea Syndrome
Functional Magnetic Resonance Imaging in Patients With Obstructive Sleep Apnea Syndrome
The obstructive sleep apnea syndrome (OSAS) involves recurrent sleep-related upper airways (UA) collapse. UA mechanical properties and neural control are altered, imposing a mechanical load on inspiration.
- Trial name
- IRM SAOS (NCT05147649)
- Testing
- functional magnetic resonance imaging
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Basic Auditory Processes, Emotional Perception
Auditory Processes and Emotional Perception in Schizophrenia
Schizophrenia is a mental illness with a variety of clinical symptoms that can be regrouped into 2 categories: positive and negative symptoms.
- Conditions
- Basic Auditory Processes, Emotional Perception, Source Monitoring Deficits
- Trial name
- AUDISPACE (NCT04768335)
- Testing
- cognitive experiments' session
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Intellectual Disability, Exercise
Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability
Adults with intellectual disabilities (ID) have significantly lower levels of fitness compared to the general population. The health benefits of enhanced muscular strength in the general population are well established.
- Conditions
- Intellectual Disability, Exercise, Obesity
- Trial name
- NCT04616638
- Testing
- Resistance Training for Empowerment (RT-POWER), A traditional RT intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Delaware