Clinical trials: Functional Neurological Disorder
Spinal Cord Injury
Intermittent Hypoxia Elicits Prolonged Restoration of Motor Function in Human SCI
The goal of the study is to determine whether repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) will improve limb function after spinal cord injury.
- Trial name
- NCT01272349
- Testing
- Acute intermittent hypoxia, Room air
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Emory University
Urea Cycle Disorders
Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function
This diagnostic study will be performed to investigate the performance of the urea cycle in healthy subjects, asymptomatic carriers of Urea Cycle Disorders (UCD) mutations and subjects with genetically proven urea cycle…
- Trial name
- NCT01549015
- Testing
- oral administration of Sodium [1,2-13C]-Acetate
- Where
- 4 sites in Germany
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Cytonet GmbH & Co. KG
Sports Physical Therapy
Comparative Effects of Spencer Muscle Energy Technique Versus Post Facilitation Stretch Among Fast Bowlers
This study compares the effectiveness of Spencer Muscle Energy Technique and Post Facilitation Stretch in reducing shoulder pain in 32 fast bowlers aged 18-35.
- Trial name
- NCT07062926
- Testing
- Spencer Muscle Energy Technique, Post Facilitation Stretch
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Temporomandibular Joint Dysfunction Syndrome
Effect of Progressive Neck Motor Control Exercises on Temporomandibular Joint Dysfunction
The primary aim of this study was to investigate the effects of progressive neck motor control exercises on craniocervical pain, posture, function and kinesiophobia in different types of temporomandibular dysfunction.
- Trial name
- NCT06148818
- Testing
- Progressive neck motor control exercise therapy, Patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Multiple Sclerosis
Cognitive Function in Multiple Sclerosis
The aim of the study is to investigate the relationship between cognitive function, functional capacity, cognitive reserve and reaction time in patients with multiple sclerosis.
- Trial name
- NCT06084182
- Testing
- Cognitive function, cognitive reserve, functional capacity, reaction time, strength, fatigue, depression and general health assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Inonu University
Autonomic Nervous System Diseases
PET Scan in Patients With Neurocardiologic Disorders
This study is designed to use PET scans in order to measure activity of the sympathetic nervous system. The sympathetic nervous system is the portion of the nervous system that maintains a normal supply of blood and fuel to…
- Trial name
- NCT00001418
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Carpal Tunnel Syndrome (CTS), Diabetic Polyneuropathy
Impact of Diabetic Polyneuropathy on Carpal Tunnel Syndrome: Shear Wave Elastography, Ultrasound, and Hand Function
This observational study examines changes in the median nerve in patients diagnosed with diabetic polyneuropathy (DPN) and carpal tunnel syndrome (CTS) using shear wave elastography, microvascular imaging, and cross-sectional…
- Conditions
- Carpal Tunnel Syndrome (CTS), Diabetic Polyneuropathy, Shear Wave Elastography, Median Nerve
- Trial name
- NCT06933511
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Spinal Cord Injuries
Effects of Caffeine and Intermittent Hypoxia on Leg Function in Human Spinal Cord Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323698
- Testing
- Caffeine, AIH
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Peripheral Neuropathy Pain, Carpal Tunnel Syndrome (CTS)
Median and Ulnar Nerve Function in Tattoo Artists
This case-control study aims to investigate the effects of occupational hand-arm vibration exposure on median and ulnar nerve functions in tattoo artists.
- Conditions
- Peripheral Neuropathy Pain, Carpal Tunnel Syndrome (CTS), Cubital Tunnel Syndrome
- Trial name
- NCT07496398
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Gazi University
Spinal Cord Injury, Spinal Cord Disease
Paired Spinal Cord and Peripheral Nerve Stimulation to Recover Hand Function in SCI
Individuals who suffer a spinal cord injury in the neck region have difficulty using their hands due to paralysis and/or weakness of their arms and hand muscles.
- Conditions
- Spinal Cord Injury, Spinal Cord Disease, Spinal Cord Injuries (SCI)
- Trial name
- NCT06698224
- Testing
- Spinal cord transcutaneous stimulation, Paired spinal cord and peripheral nerve stimulation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Diabetic Neuropathy
NIR- and Multifrequent Impedance Spectroscopy on the Skin in Type 1 Diabetes
The aim of the study is to examine the suitability to detect diabetic neuropathy using NIR and impedance.
- Trial name
- NIR (NCT01707979)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lise Tarnow
Craniocerebral Trauma
The Acute Effect of Boxing on Balance, Neuropsychological, and Visual Functions
Prior research has investigated the effect of repetitive head trauma as it relates to physiological and psychological function. Boxing is one particular sport which predisposes athletes to a large amount of head impacts.
- Trial name
- NCT02442882
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Brain Tumor, Brain Pathology
Can we Use Resting-state fMRI and CSD Fiber Tractography for Presurgical Mapping?
This prospective study aims to investigate and validate the use of resting-state functional MRI (rs-fMRI) and high angular resolution diffusion imaging (HARDI), specifically constrained spherical deconvolution (CSD) tractography…
- Conditions
- Brain Tumor, Brain Pathology, Epilepsy, Vascular Malformations, Brain
- Trial name
- NCT06040580
- Where
- Belgium
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Neurodegenerative Diseases
Exploring the Recovery Function of Sleep in Neurodegeneration
The overall objective of this study is to identify the best approach for assessing the recovery function of sleep in neurodegenerative diseases associated with abnormal protein aggregation with regard to the conception of future…
- Trial name
- RFSN (NCT05402488)
- Testing
- Auditory stimulation
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Alzheimer's Disease
Alzheimer's Caregiver Communication Study
The point of this research is to improve the communicative relationship between the caregiver and care receiver. It is input from the caregiver on these communicative behaviors that will inform the process of understanding how to…
- Trial name
- NCT00182988
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Chest Tube Removal, Heart; Surgery, Heart, Functional Disturbance as Result
Foot Reflexology to Reduce Pain and Anxiety Before Chest Tube Removal
In open heart surgeries, patients experience severe pain due to tissue trauma, damage to intercostal nerves, and muscle spasm due to pulling tubes from the mediastinal space and between the pleural leaves pull during chet tube…
- Conditions
- Chest Tube Removal, Heart; Surgery, Heart, Functional Disturbance as Result, Pain, Anxiety
- Trial name
- NCT05032469
- Testing
- Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Baskent University
Stroke, Stroke with Hemiparesis
Study of Hemodynamic Markers of Upper Extremity Motor Dysfunction in Stroke Patients Using Functional Near Infrared Spectroscopy (fNIRS)
The aim of the study was to explore potential pathways for recovery and adaptation of the motor cortex by examining cerebral blood flow characteristics and hemodynamic markers analyzed by functional near-infrared spectroscopy…
- Conditions
- Stroke, Stroke with Hemiparesis, Stroke, Ischemic
- Trial name
- NCT06806397
- Testing
- Stimulus response task
- Where
- 2 sites in Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Stroke
Motor Relearning Program and Aerobic Exercise in Postural Stability and Lower Limb Function in Subacute Stroke Patients
The aim of the study is to determine combined effects of MRP and aerobic exercise in postural stability and lower limb function in subacute stroke patients
- Trial name
- NCT06476782
- Testing
- Motor Relearning Program(MRP) and aerobic exercise, Motor Relearning Program(MRP)
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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