Clinical trials: Functional Outcomes
Knee Pain, Patellofemoral Pain Syndrome
Mikhled Knee Exercise Program With and Without Stecco Fascial Manipulation Effect in Patellofemoral Pain Syndrome
To compare the effects of the Mikhled Knee Exercise Program with and without Stecco Fascial Manipulation on pain, range of motion, and functional outcomes Patellofemoral Pain Syndrome.
- Conditions
- Knee Pain, Patellofemoral Pain Syndrome, Patellofemoral Pain (PFPS), Fascial Manipulation
- Trial name
- MKEP (NCT07716163)
- Testing
- Mikhled Knee Exercises with Stecco Fascial Manipulation, Mikhled Knee Exercise Program (MKEP)
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Healthy, Vitamin D Deficiency
Can Correction of Low Vitamin D Status in Infancy Program for a Leaner Body Composition?
One in four infants are born with low amounts of vitamin D stored in their body. This study is designed to test whether improving vitamin D status quickly after birth helps infants to build muscle and to normalize growth.
- Conditions
- Healthy, Vitamin D Deficiency, Gestational Diabetes
- Trial name
- NCT02563015
- Testing
- cholecalciferol, Reference 400
- Where
- Canada
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- McGill University
Constipation - Functional
Adherence/Outcomes After Use of Constipation Action Plan
Adherence to recommendations for treatment of chronic constipation in pediatric population is often poor. This study is attempting to improve adherence, and outcomes, by implementing a trial of a constipation action plan plus…
- Trial name
- NCT03821532
- Testing
- Constipation Action Plan
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Bronchopulmonary Dysplasia
Respiratory Oscillometry for the Prediction of Bronchopulmonary Dysplasia
The goal of this observational study is to learn about the correlation between respiratory system reactance, as assessed by respiratory oscillometry, and respiratory outcomes in preterm infants born before 32 weeks of gestation.
- Trial name
- REACT (NCT05986032)
- Testing
- Respiratory Oscillometry
- Where
- 6 sites in Austria, Italy and 3 more
- Volunteers
- 150 people
- Sponsor
- Fondazione IRCCS San Gerardo dei Tintori
Dementia, Lewy Body
ANeED Joint Effort 21: eHealth and a PPI Program in Dementia With Lewybodies (DLB)
The goal of the study is to develop predictive algorithms and digital biomarkers to capture disease fluctuations in (prodromal) dementia with lewybodies (DLB) patients and to improve treatment, diagnosis and prognosis of the…
- Trial name
- JointEffort21 (NCT05773443)
- Testing
- Digital biomarkers
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- University of Bergen
Orofacial Myofunctional Disorders
The Effect of Orofacial Myofunctional Therapy on Neuromuscular Outcomes and Orofacial Function in Children and Adolescents in Estonia
The aim of the present study is to evaluate the effects of semi-standardized myofunctional therapy on the functional and neuromuscular characteristics of the orofacial system in children and adolescents aged 7-14 years using a…
- Trial name
- NCT07828769
- Testing
- Semi-standardized Orofacial Myofunctional Therapy
- Where
- Estonia
- Volunteers
- 80 people
- Sponsor
- Tartu University Hospital
Achilles Tendinopathy (AT)
Lower-Extremity Kinetic Chain Exercise Program for Achilles Tendinopathy
Achilles tendinopathy is a common condition that causes pain, stiffness, and reduced function of the Achilles tendon. It can affect both physically active individuals and the general adult population, often making everyday…
- Trial name
- LEKC-AT (NCT07730866)
- Testing
- Lower-Extremity Kinetic Chain Exercise Program, Conventional Exercise Program
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- May University in Cairo
Lymphedema of the Head and Neck
Head and Neck Cancer Patient Symptom and Oncologic Outcomes
This trial investigates a new approach using a mobile three-dimensional (3D) scanning application for volumetric measurement of the head and neck region in patients with head and neck lymphedema.
- Trial name
- NCT05243069
- Testing
- Imaging Technique
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Traumatic Brain Injury
Blood NfL and Functional Outcomes After Moderate-to-Severe TBI
Prospective cohort study of 150 adults with moderate-to-severe TBI. Blood NfL is measured at admission, day 1, and day 3 to examine its relationship, alone and with CT imaging, to 3-month functional outcome (GOSE).
- Trial name
- NCT07901712
- Testing
- neurofilament light chain ECLIA
- Volunteers
- 175 people
- Sponsor
- Rutgers, The State University of New Jersey
Thoracic Outlet Syndrome
Effect of Low-Power Laser Therapy on Pain and Functional Outcomes in Patients With Thoracic Outlet Syndrome
The purpose of this study is to evaluate the effect of low-power laser therapy on pain intensity and functional outcomes in patients diagnosed with Thoracic Outlet Syndrome (TOS).
- Trial name
- LPLT-TOS (NCT07535853)
- Testing
- Low level laser therapy, Therapeutic Ultrasound, Physical Therapy Exercises
- Volunteers
- 40 people
- Sponsor
- Cairo University
Attention Deficit Disorder With Hyperactivity
A Functional Outcomes Study With Atomoxetine-Hydrochloride and Placebo in Adults With Attention-Deficit/Hyperactivity Disorder
The overall primary objective of this study is to test the hypothesis that, compared with placebo,administration of atomoxetine will result in an improved work productivity.
- Trial name
- NCT00190931
- Testing
- Atomoxetine Hydrochloride
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Eli Lilly and Company
Low Level Laser Therapy, Temporomandibular Joint Disorders
The Efficacy of Low-level Laser Therapy (LLLT) as an Adjunct Treatment for Pain and Functional Outcomes in Temporomandibular Disorders (TMD)
The goal of this clinical trial is to evaluate the effectiveness of low-level laser therapy (LLLT) as an adjunct treatment in patients aged 18 years and older diagnosed with temporomandibular disorders (TMD).
- Conditions
- Low Level Laser Therapy, Temporomandibular Joint Disorders, Pain, Physical Therapy
- Trial name
- LLLT IN TMD (NCT07840495)
- Testing
- LLLT
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Pancreatic Adenocarcinoma, Pancreatic Cysts
Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors
This multicenter randomized trial aims to primarily assess and compare the functional recovery of patients who undergo open versus robotic pancreaticoduodenectomy for benign and malignant lesions of the head of the pancreas.
- Conditions
- Pancreatic Adenocarcinoma, Pancreatic Cysts, Pancreatic Endocrine Tumors, Chronic Pancreatitis
- Trial name
- PORTAL (NCT04400357)
- Testing
- Robotic pancreaticoduodenectomy, Open pancreaticoduodenectomy
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Ruijin Hospital
High Degree Second Degree Atrioventricular Block, Complete Heart Block
RAFT-TAVR PACE: LBBAP vs. RVP Post-TAVR in Patients Requiring PPI
The RAFT-TAVR PACE study is a clinical trial designed to compare two types of heart pacing methods in patients who develop conduction problems after undergoing a transcatheter aortic valve replacement (TAVR) procedure.
- Conditions
- High Degree Second Degree Atrioventricular Block, Complete Heart Block, Heart Failure, Transcatheter Aortic Valve Replacement (TAVR)
- Trial name
- RAFT-TAVR PACE (NCT06857201)
- Testing
- Left Bundle Branch Area Pacing, Right Ventricular Pacing
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Knee Replacement, Arthroplasty
The Effect of Patellar Eversion on Functional Outcomes in Primary Total Knee Arthroplasty
Short and long term outcomes of total knee arthroplasty patients surgically exposed with patellar eversion are compared to those patients exposed by laterally retracting the patella.
- Conditions
- Total Knee Replacement, Arthroplasty, Patella
- Trial name
- NCT01777009
- Testing
- Primary Total Knee Replacement Surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwell Health
Prostate Cancer (Adenocarcinoma)
Robot-Assisted Radical Prostatectomy: the HOOD Technique Versus Standard Anterior Reconstruction
This prospective, non-randomized cohort study included consecutive patients undergoing robotic-assisted laparoscopic radical prostatectomy (RARP) between January 2024 and January 2026 following ethics committee approval.
- Trial name
- NCT07417475
- Testing
- Prostatectomy with anterior-posterior renconstruciton, Prostatectomy with HOOD techinque
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Araz Musaev
Quality of Life, Graft-vs-Host Disease
Cognitive Function and Patient-Reported Quality of Life Outcomes Investigation in Patients Taking Vorinostat
Psychological well-being and cognitive function will be measured in patients enrolled on the primary study, NCT01790568, a phase 2 trial of vorinostat plus tacrolimus and methotrexate to prevent graft versus host disease…
- Trial name
- NCT02409134
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Sung Choi, M.D.
Schizophrenia
Cognitive Adaptive Training for Improving Medication Adherence, Symptoms, and Function in People With Schizophrenia
This study will compare the effectiveness of three treatments in improving medication adherence, symptoms, and function in people with schizophrenia.
- Trial name
- NCT00455663
- Testing
- Cognitive Adaptation Training, Pharm-Cognitive Adaptation Training, Treatment as usual
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Aging, Cognitive Decline
Impact of a Novel Brain Longevity Supplement Containing the Postbiotic Urolithin A (Mitopure) on Cognitive Function and Related Health Outcomes
This is a parallel group, randomized, double-blind, placebo-controlled clinical study assessing the safety and effects of a novel nutritional product on self-reported cognitive function and health in adults that reside in the…
- Conditions
- Aging, Cognitive Decline, Brain Fog, Cognitive Function
- Trial name
- CLARITY (NCT07060898)
- Testing
- Active Product
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Postoperative Nausea, Postoperative Vomiting
Intravenous Fluids After Laparoscopic Cholecystectomy
Perioperative intravenous fluid (IV) administration has been the standard procedure since 1832 and, is a widely used practice sometimes under inadequate criteria.
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Renal Function Abnormal, Hunger
- Trial name
- NCT03142464
- Testing
- Suspension of the IV fluids
- Volunteers
- 100 people
- Sponsor
- Federal University of Minas Gerais
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