Clinical trials: GAD
Breast Cancer Female NOS, General Anxiety Disorder
Psychological State, Immunotherapy Response, and Multi-Omics Signatures in TNBC
This study aims to evaluate whether psychological status affects the response to neoadjuvant immunotherapy in triple-negative breast cancer (TNBC) and how it relates to immune changes during treatment.
- Conditions
- Breast Cancer Female NOS, General Anxiety Disorder, Depressive Disorder
- Trial name
- SCHBCC-N0105 (NCT07290153)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fudan University
Generalized Anxiety Disorder
Electroacupuncture for Generalized Anxiety Disorder: Clinical Efficacy and Neuroimaging Mechanisms
This study aims to evaluate the clinical efficacy and safety of electroacupuncture (EA) as an adjunctive treatment for generalized anxiety disorder (GAD).
- Trial name
- NCT07392645
- Testing
- Electroacupuncture (EA), Medication
- Where
- China
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Lishu Gao
Generalized Anxiety Disorder
Efficacy and Safety Study of Seroquel SR in the Treatment of Generalized Anxiety Disorder
The primary purpose of this study is to evaluate the efficacy of (SEROQUEL SR™ ) quetiapine fumarate sustained-release (SR) compared to placebo in the treatment of anxiety symptoms in patients with generalized anxiety disorder…
- Trial name
- SILVER (NCT00322595)
- Testing
- Quetiapine fumarate, Paroxetine
- Where
- 86 sites in Argentina, Bulgaria and 13 more
- Volunteers
- 800 people
- Sponsor
- AstraZeneca
Depressive Symptoms, Trauma, Psychological
Sharing HaRT in New Expanses
The goal of this parallel cluster randomized control (CRT) trial is to evaluate a group-based mind-body intervention (Move with HaRT) in survivors of human trafficking. The main study aims are: 1.
- Conditions
- Depressive Symptoms, Trauma, Psychological, Anxiety Generalized
- Trial name
- SHiNE (NCT06237439)
- Testing
- Move with HaRT
- Where
- Uganda
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"
The investigators are examining whether difficulties with cognitive control (i.e., the ability to stop one's thought process and shift attention) is a common problem across three types of repetitive, negative thinking: obsessions…
- Conditions
- Obsessive-Compulsive Disorder, Generalized Anxiety Disorder, Major Depressive Disorder
- Trial name
- NCT03414619
- Testing
- Cognitive Control Tasks and Script Driven Imagery
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Analogue Generalized Anxiety Disorder
The Resistance Exercise Training for Worry Trial
This protocol details the full methods of two parallel, randomized controlled trials of an eight-week resistance exercise training intervention compared to a wait-list control condition among young adults with and without…
- Trial name
- NCT04116944
- Testing
- Resistance exercise training, Wait-list
- Where
- Ireland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Generalized Anxiety Disorder
Self-selected or Predetermined Internet-based Treatment for Generalized Anxiety Disorder With Different Types of Support
This study evaluates two types of internet-based treatments for generalized anxiety disorder and two types of support. The treatments are a predetermined program for generalized anxiety disorder and a self-selected treatment.
- Trial name
- NCT03807193
- Testing
- Self-selected treatment, Predetermined treatment, Weekly support
- Where
- Sweden
- Volunteers
- 85 people
- Sponsor
- Linkoeping University
Generalized Anxiety Disorder
Cognitive Behavioral Therapy (CBT) for Latinos With Generalized Anxiety Disorder in the General Medical Sector
The purpose of this project is to implement culturally adapted Cognitive Behavioral Therapy (CBT) based interventions in general health settings that are delivered to reduce Generalized Anxiety Disorder (GAD) symptoms, increase…
- Trial name
- NCT01203293
- Testing
- Cognitive behavior based therapy, Treatment as usual
- Where
- Puerto Rico
- Volunteers
- 90 people
- Sponsor
- University of Puerto Rico
Depression
Reward-Related Processes and Brain Function
This study will examine and compare brain changes during decision-making in healthy adolescents and adolescents who are anxious or depressed.
- Trial name
- NCT00029588
- Where
- 2 sites in United States
- Volunteers
- 241 people
- Sponsor
- National Institute of Mental Health (NIMH)
General Anxiety Disorders, Systemic Inflammation
Effects of Mulberry Juice on Inflammatory Status and Clinical Symptoms in Patients With General Anxiety Disorder
Anxiety and depression are normally associated with inflammation reactions and interleukin (IL) related pathways are most evidently involved.
- Conditions
- General Anxiety Disorders, Systemic Inflammation, Interleukin
- Trial name
- NCT03935061
- Testing
- Mulberry juice
- Where
- Taiwan
- Volunteers
- 104 people
- Sponsor
- Taipei Medical University
Anxiety
Duloxetine vs Placebo in the Treatment of General Anxiety
To see if duloxetine 60 to 120 mg once daily (QD) is better than placebo in the treatment of generalized anxiety disorder (GAD).
- Trial name
- NCT00475969
- Testing
- duloxetine
- Where
- United States
- Volunteers
- 327 people
- Sponsor
- Eli Lilly and Company
Anxiety Disorders
A Study To Evaluate PRX-00023 In Patients With Generalized Anxiety Disorder (GAD)
This is a randomized, double-blind, placebo controlled, multi-center outpatient study, in adults with GAD. Patients 18-65 years of age, with the diagnosis of GAD according to DSM-IV criteria, who fulfill the inclusion/exclusion…
- Trial name
- NCT00248183
- Testing
- PRX-00023
- Where
- 20 sites in United States
- Volunteers
- 310 people
- Sponsor
- Epix Pharmaceuticals, Inc.
Anxiety, Generalized Anxiety Disorder
Use of CBD in the Treatment of Anxiety
This study will examine the doses, safety, and test the preliminary efficacy of hemp-derived CBD product for improving anxiety symptoms and sleep disturbances among individuals with anxiety.
- Conditions
- Anxiety, Generalized Anxiety Disorder, Sleep Problems
- Trial name
- NCT06672666
- Testing
- Hemp Derived Cannabidiol Extract
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Sleep Difficulties in Pediatric Anxiety Disorder, Generalized Anxiety Disorder
Sleep, Mood, and Behavior Study
The purpose of this study is to assess whether improving sleep in children and adolescents with anxiety disorder will further enhance affective, clinical, and social functioning.
- Conditions
- Sleep Difficulties in Pediatric Anxiety Disorder, Generalized Anxiety Disorder, Separation Anxiety Disorder, Social Phobia
- Trial name
- NCT00787397
- Testing
- Cognitive Behavioral Therapy-Sleep
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Pittsburgh
Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD)
Impact of Anxiety and Depression on Implicit and Explicit Memory Performance
This study examines the effect of anxiety and depression on memory processes, focusing on implicit and explicit memory. Implicit memory involves unconscious recall, such as recognizing familiar words without effort, while…
- Conditions
- Major Depressive Disorder (MDD), Generalized Anxiety Disorder (GAD), Memory Bias, Implicit Memory
- Trial name
- ADEM (NCT06663423)
- Where
- Iran
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Anxiety
Biological and Psychological Markers After Intervention in Adults With GAD
This clinical trial inestigates the effects of transcranial direct current stimulation (tDCS) on anxiety symptoms in adult women with clinically relevant anxiety levels.
- Trial name
- AnsitDCS (NCT07116980)
- Testing
- 'Transcranial Direct Current Stimulation - tDCS
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Generalized Anxiety Disorder, Anxiety
Muscle Relaxation Therapy With Odorant Cue
A novel procedure for generalized anxiety disorder where an odorant cue is paired with the state of deep relaxation during training.
- Trial name
- NCT00208910
- Testing
- Odorant Cue
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Generalized Anxiety Disorder, Adolescent - Emotional Problem
Behavioural Experiments for Generalized Anxiety in Adolescents - Pilot Study
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry and anxiety. In adolescents, this condition can seriously impact their development, academic performance, and social…
- Trial name
- EC-II-Ado-P (NCT06282133)
- Testing
- Behavioural Experiments for Intolerance of Uncertainty
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universite du Quebec en Outaouais
Generalized Anxiety Disorder
Open Trial of an ACT Skills Group and Mobile App for Worry
This study is an open trial of acceptance and commitment therapy (ACT) groups combined with a mobile app for the treatment of Generalized Anxiety Disorder (GAD).
- Trial name
- NCT03709433
- Testing
- ACT groups and mobile app
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Utah State University