Clinical trials: Gait Dysfunction
Cognitive Impairment
Dual Task Aerobic Exercise for Older Adults With Cognitive Impairment (HM2)
The investigators proposed research will establish whether combining aerobic exercise with cognitive challenges is feasible and effective in community dwelling older adults with early signs of cognitive impairment.
- Trial name
- HM2 (NCT01572311)
- Testing
- Exercise Intervention, Exercise Control
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Parkwood Hospital, London, Ontario
Mild Cognitive Impairment, Mild Dementia
Gait, cOgnitiOn & Decline (GOOD)
The main objective of the GOOD initiative was to determine which spatio-temporal gait parameters and/or combination(s) of spatio-temporal gait parameters best differentiate between cognitively healthy individuals (CHI), patients…
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Moderate Dementia, Healthy
- Trial name
- NCT02350270
- Testing
- gait and cognitive testing
- Where
- France
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Pelvic Floor Disfunction
The Impact of Osteopathic Manipulative Treatment on Pelvic Floor Dysfunction, Activity, and Gait in Female Runners
This study will examine whether osteopathic manipulative treatment (OMT) affects pelvic floor symptoms, physical activity, and running gait in female runners.
- Trial name
- NCT07812285
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Elizabeth Perrero
Measurement Properties of 5iTUG, Physical Disability
Evaluation of the Measurement Properties of a 5 Time Repeated Instrumented Timed Up and Go (5iTUG)
In order to tailor interventions, objective assessments of physical function is needed. A limitation of several of today's clinical assessments is that they require too much time and/or space.
- Conditions
- Measurement Properties of 5iTUG, Physical Disability, Balance, Cognitive Impairment
- Trial name
- 5iTUG (NCT03769220)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Gait Apraxia, Mild Cognitive Impairment
Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study
Motor slowing and cognitive slowing are more prevalent as we age. Importantly, the presence of both in an older person increases their risk of having dementia by ten times.
- Conditions
- Gait Apraxia, Mild Cognitive Impairment, Subjective Cognitive Impairment, Cerebral Atrophy
- Trial name
- NCT03020381
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Manuel Montero Odasso
Mild Cognitive Impairment
SYNchronizing Exercises, Remedies in GaIt and Cognition
The proposed SYNERGIC trial is uniquely designed to evaluate the effect of aerobic and progressive resistance training exercises, combined with cognitive training and Vitamin D3 supplementation, in cognition and mobility in older…
- Trial name
- SYNERGIC (NCT02808676)
- Testing
- Vitamin D3, Exercises (E), Cognitive Training (CT)
- Where
- 6 sites in Canada
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment
Pre-demential Motoric Cognitive Risk Syndrome in Ageing Subjects
The main aim of the study is to characterize and understand the pathological mechanisms underlying the motoric cognitive risk syndrome, which is a predictor of Alzheimer disease.
- Conditions
- Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment, Alzheimer Disease, Dementia
- Trial name
- PRESAGE (NCT05640141)
- Testing
- MRI evaluation, Actimetry & IMU, Gait evaluation
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Fallers, Mild Cognitive Impairment
Temporal Relations and Exercise Interventions of Various Gait and Cognitive Domains in Older Adults
The effectiveness of conventional exercise, tai chi chuan and health education/usual physical activity over a 6-month intervention period in improving primary outcomes and secondary outcomes in older mild cognitive impairment…
- Trial name
- NCT03839563
- Testing
- Exercise
- Where
- Taiwan
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Tibialis Posterior Dysfunction, Emg
Pilot Study to Develop Protocols for Recording Tibialis Posterior EMG
This is an observational pilot study to allow us to create a normal database of muscle function of one of the muscles in the back of the leg (tibialis posterior).
- Trial name
- NCT06131359
- Testing
- Fine wire EMG and Force Frame muscle strength testing
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Sacroiliac Dysfunction
Sacroiliac Joint Dysfunction Consequences and Its Reversal by Manipulation
Sacroiliac joint dysfunction (ASI) is an alteration in the normal biomechanics of the joint, which leads to hypomobility or hypermobility of that joint.
- Trial name
- LOUIS (NCT06710535)
- Testing
- Manual Manipulation
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Multiple Sclerosis, Gait Disorders, Neurologic
Measurement and Training of Dual-Task of Gait in Persons With Multiple Sclerosis
The purpose of this study is to determine the utility of a performance measure for the dual-task of gait and considering people with multiple sclerosis have both cognitive and motor problems, the secondary aim of this study is to…
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Cognitive Impairment
- Trial name
- MS (NCT03536299)
- Testing
- Dual-task gait, Single-task gait
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Parkinson's Disease
Cholinergic Mechanisms of Gait Dysfunction in Parkinson's Disease
Balance and gait problems cause severe impairments for people with Parkinson's disease In some Parkinson's disease patients the investigators see a loss of acetylcholine in the brain.
- Trial name
- UDALL (NCT02458430)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Mobility Limitation, Functional Disturbance
Help Optimise and Mobilise Elders (H.O.M.E)
During hospitalisations, older inpatients commonly face issues such as immobility, loss of independence, and functional decline.
- Trial name
- HOME (NCT05484063)
- Testing
- Multicomponent, mobility-focused intervention
- Where
- 2 sites in Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- JurongHealth
Dementia, Dementia, Mixed
Uppsala-Dalarna Dementia and Gait Project
UDDGait™ is a multidisciplinary research project with the overreaching goal of providing an aid for early identification of cognitive impairment and risk of dementia development, thereby providing a basis for adequate symptom…
- Conditions
- Dementia, Dementia, Mixed, Dementia Senile, Dementia of Alzheimer Type
- Trial name
- UDDGait™ (NCT05893524)
- Testing
- Timed Up-and-Go (TUG single-task), Timed Up-and-Go dual-task (TUGdt), Clinical functional assessment
- Where
- 2 sites in Sweden
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Dalarna University
Aging, Cognitive Decline
Omega-3 Fatty Acids and Exercise on Mobility and Cognition in Older Women
The study will provide insight into how lifestyle-related interventions, specifically nutrition and exercise can impact the health of older women.
- Trial name
- MOBILE (NCT03228550)
- Testing
- Efamol Active 50+, Aerobic exercise
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Upper Extremity Dysfunction, Gait, Unsteady
The Effect of Improvement in Function on Foot Pressure, Balance and Gait in Children With Upper Extremity Affected
It has been shown that movements of the upper extremity during walking are associated with lower extremity mobility. For example, when walking at a slow pace, the swing frequency of the arms is 2: 1 compared to the legs, while…
- Conditions
- Upper Extremity Dysfunction, Gait, Unsteady, Juvenile Idiopathic Arthritis, Balance
- Trial name
- NCT04671524
- Testing
- Exercise protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Post-acute Sequelae of SARS-CoV-2 Infection
Cognitive-Sensorimotor Function in Long-COVID
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance.
- Trial name
- NCT06850350
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development