Clinical trials: Gastrointestinal Tumor Surgery
Pancreatic Cancer, Surgery--Complications
ERAS Protocol in Pancreaticoduodenectomy and Total Pancreatectomy
In the study, the enhanced recovery after surgery (ERAS) program is applied to total pancreatectomy (TP) and low-risk pancreaticoduodenectomy (PD) patients identified by a small number of acinar cells in the cut edge of the…
- Conditions
- Pancreatic Cancer, Surgery--Complications, Pancreatic Fistula, Delayed Gastric Emptying
- Trial name
- NCT03757455
- Testing
- ERAS protocol preoperative actions, ERAS protocol intraoperative actions, ERAS protocol postoperative actions
- Where
- Finland
- Volunteers
- 35 people
- Sponsor
- Tampere University Hospital
Oesophageal Cancer, Gastric Cancer (Diagnosis)
REcovery After Cancer Application
The RECapp study is a clinical trial evaluating a digital tool designed to support patients recovering from surgery for oesophageal or stomach cancer. The goal is to reduce symptoms and improve quality of life during recovery.
- Trial name
- RECapp (NCT07642492)
- Testing
- The RECapp platform
- Where
- 7 sites in Sweden
- Volunteers
- 250 people
- Sponsor
- Karolinska Institutet
Ulcerative Colitis (Disorder), Familial Adenomatous Polyposis (FAP)
LATA-IBD TRIAL a Controlled Feasibility Study for the Introduction of Transanal Minimally Invasive IPAA-Surgery. Evaluation of Operative Results and Bowel Function After Introducing Transanal IPAA-surgery to Replace Conventional Laparoscopic IPAA-surgery.
This study compares the operative and functional outcomes of adding a transanal pathway to laparoscopic pelvic pouch surgery. The transanal pathway enables the surgeon to have better control when dividing the rectum and it may…
- Trial name
- LATA-IBD (NCT07278687)
- Where
- Sweden
- Volunteers
- 39 people
- Sponsor
- Sahlgrenska University Hospital
Colo-rectal Cancer, Colon Cancer
Delayed Colorectal Cancer Care During Coronavirus Disease (COVID-19) Pandemic (DECOR-19)
To understand and analyse the global impact of COVID-19 on outpatient services, inpatient care, elective surgery, and perioperative colorectal cancer care, a DElayed COloRectal cancer surgery (DECOR-19) survey was conducted in…
- Conditions
- Colo-rectal Cancer, Colon Cancer, Rectal Cancer, Oncology
- Trial name
- DECOR-19 (NCT04488549)
- Testing
- Survey
- Where
- Italy
- Volunteers
- 1,051 people
- Sponsor
- Treviso Regional Hospital
Peritoneal Carcinomatosis
Peritoneal Carcinomatosis Extent Evaluation: Radiologic, Laparoscopic and Pathologic.
pathologically proved ovarian cancer patients that underwent contrast enhanced abdomino-pelvic CT and diagnostic laparoscopy before cytoreductive surgery (CRS) will be included in the study.
- Trial name
- NCT03798132
- Testing
- laparoscopy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Shimaa Abdalla Ahmed
Colorectal Cancer
Radiation Therapy and Chemotherapy Followed by Surgery and Combination Chemotherapy in Treating Patients With Rectal Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00021398
- Testing
- fluorouracil, leucovorin calcium, conventional surgery
- Where
- 17 sites in United States
- Volunteers
- 23 people
- Sponsor
- Fox Chase Cancer Center
Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Carcinoma
Standard or Prolonged Neoadjuvant Chemotherapy Before Surgery for BR/LAPC
The goal of this multicenter randomized controlled phase III trial is to compare two durations of neoadjuvant chemotherapy (NAT) with mFOLFIRINOX or gemcitabine-nab-paclitaxel (GnP) before attempt for surgical resection in…
- Conditions
- Locally Advanced Pancreatic Adenocarcinoma, Borderline Resectable Pancreatic Carcinoma, Pancreas Cancer, Neoadjuvant Chemotherapy
- Trial name
- ADVANTAGE (NCT06714604)
- Testing
- FOLFIRINOX or gemcitabine-nab-paclitaxel
- Where
- Sweden
- Volunteers
- 432 people
- Sponsor
- Sahlgrenska University Hospital
Colon Cancer
Prospective, Controlled, Randomized Multicentric Study on the Management of the Vesical Catheter in Colon Surgery.
INTRODUCTION: Recommendations for peroperative bladder catheterization remain a controversial issue since it is a procedure that is not without complications.
- Trial name
- NCT04070898
- Testing
- Remove urinary catheter after surgery
- Where
- Spain
- Volunteers
- 416 people
- Sponsor
- Corporacion Parc Tauli
Pancreas Cancer, Pancreas Disease
Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy
Despite improvements and advances in pancreas surgery, about 30-35% of patients who have pancreas surgery develop a type of complication called a pancreatic fistula.
- Conditions
- Pancreas Cancer, Pancreas Disease, Pancreas Adenocarcinoma, Pancreas; Fistula
- Trial name
- PATCH-DP (NCT03410914)
- Testing
- Hemopatch
- Where
- 7 sites in Canada
- Volunteers
- 52 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pancreatic Neoplasm
Palliative Care Consultation to Improve Communication for Patients Considering Surgery for a Pancreatic Neoplasm
This clinical trial evaluates a palliative care consultation for improving communication between providers and patients considering surgery for a pancreatic neoplasm.
- Trial name
- NCT06545344
- Testing
- Best Practice, Palliative Care Consultation, Survey Administration
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Colorectal Cancer, Postoperative Complication
Comparing Immediate Removal and Postoperative 1 Day of Urinary Catheter After Colorectal Cancer Surgery
The enhanced recovery after surgery (ERAS) program is widely applied in colorectal cancer surgery. Among the early recovery programs after surgery, the timing of removal of the urinary catheter after surgery has been emphasized…
- Conditions
- Colorectal Cancer, Postoperative Complication, Urinary Retention Postoperative, Enhanced Recovery After Surgery
- Trial name
- POUR (NCT06769087)
- Testing
- Immediate urinary catheter removal, urinary catheter removal within postoperative 1day
- Where
- South Korea
- Volunteers
- 316 people
- Sponsor
- Seoul St. Mary's Hospital
ColoRectal Cancer and Inflammatory Bowel Disease
Impact of the Enhanced Recovery After Surgery System for Colorectal Surgery
This is an observational study to look at the impact of the Enhanced Recovery After Surgery system for colorectal surgery (Group 1) in shortening hospital length of stay, reducing postoperative narcotic consumption, lowering…
- Trial name
- NCT02997293
- Testing
- Enhanced Recovery protocol
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Colorectal Cancer, Surgery
Perioperative Immune Function in Patients Undergoing Colorectal Cancer Surgery
At Zealand University Hospital, Denmark, the investigators will examine the immune function of patients with colorectal cancer before and after tumor resection.
- Trial name
- TruCulture (NCT04127864)
- Testing
- Colorectal cancer surgery
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- University of Copenhagen
Gastrointestinal Cancer
The Laparotomy Study
The depth of neuromuscular blockade (NMB) during surgery may cause a clinical dilemma between optimal surgical conditions and the risk of postoperative residual blockade.
- Trial name
- NCT02140593
- Where
- Denmark
- Volunteers
- 128 people
- Sponsor
- Herlev Hospital
Colorectal Cancer, Imaging
Metabolism Imaging-genomics for Predicting the Surgical Outcomes of Colorectal Cancer
In this study, the investigators constructed an imaging-metabolism prediction model for colorectal cancer by analysing the imaging and metabolomics features of colorectal cancer, in order to further adjust and guide the treatment…
- Conditions
- Colorectal Cancer, Imaging, Metabolomics, Prognosis
- Trial name
- NCT06614660
- Testing
- Metabolism genomics and imaging genomics
- Where
- China
- Volunteers
- 800 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Cancer, Hepatic, Cancer, Esophagus
Expectation, Pain Outcomes, and Pain Medication Following Oncology Abdominal Surgery: A Cohort Study
This study includes participants undergoing major hepatic surgery, surgery in the esophagus or stomach, or major surgery on the pancreas performed at Copenhagen University Hospital, Rigshospitalet.
- Conditions
- Cancer, Hepatic, Cancer, Esophagus, Cancer, Pancreas
- Trial name
- NCT07176052
- Testing
- cancer surgery
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gastric Cancer, Adenocarcinoma
Induction Chemotherapy, Chemoradiotherapy and Surgery in Locally Advanced Gastric Cancer Patients
The aim of this study is to evaluate the efficacy of a neoadjuvant approach in patients with locally advanced gastric cancer and the identification of prognostic factors.
- Conditions
- Gastric Cancer, Adenocarcinoma, Effects of Chemotherapy, Surgery
- Trial name
- NCT02454647
- Testing
- Induction chemotherapy, Radiotherapy with concurrent chemotherapy, Salvage surgery
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Gastric Cancer
The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping
To investigate the effect of perioperative lidocaine infusion on the neutrophil extracellular trapping after minimally invasive surgery for stomach cancer
- Trial name
- NCT04868747
- Testing
- Lidocaine, normal saline
- Where
- South Korea
- Sponsor
- The Catholic University of Korea
Cancer, Sigmoid, Cancer, Rectum
Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery
The investigators hypothesize that a primary embolization, 3-4 weeks before surgery, would allow development of vascular collaterality, in particular for the marginal artery which will ensure a better colonic perfusion.
- Trial name
- AMIREMBOL (NCT03628248)
- Testing
- embolization of the inferior mesenteric artery, Inferior mesenteric artery ligation
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Colorectal Cancer, Fragility
MPI Predicts Outcome of CRC Elderly Patients (MPI=MULTIDIMENSIONAL PROGNOSTIC INDEX; CRC=COLORECTAL CANCER)
Patients aged ≥75 year scheduled for CRC surgery were studied (104 cases) and variables associated with major postoperative complications / mortality were evaluated.
- Conditions
- Colorectal Cancer, Fragility, Elderly
- Trial name
- MPI;CRC (NCT04594655)
- Testing
- surgery
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
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