Clinical trials: Generative AI
Peritoneal Dialysis (PD), Large Language Models
A Simulated Case Study of a Peritoneal Dialysis-Specialized Large Language Model Assisting Doctors in Improving Decision-Making in Peritoneal Dialysis Management
This study is a randomized controlled trial based on simulated clinical cases, aiming to establish a standardized evaluation system for PD physicians, to assess the differences in PD management quality between a workflow assisted…
- Trial name
- NCT07724327
- Testing
- Peritoneal dialysis-specialized large language model.
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Artifical Intelligence, Generative Artificial Intelligence
AI-Driven Video Avatars vs. Customized GPTs: Professional English Learning Among Nursing Students
The goal of this study is to evaluate and compare the effectiveness of two generative artificial intelligence technologies (an interactive AI video avatar vs.
- Conditions
- Artifical Intelligence, Generative Artificial Intelligence, Education, Nursing Students
- Trial name
- NCT07897422
- Testing
- Interactive AI Video Avatar, Personalized GPT Interface
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Communication
DHL Survey on Generative AI for MyChart Messaging
The purpose of this study is to understand how patients feel about the use of computer programs to create responses when they send electronic messages to their doctors.
- Trial name
- NCT06108037
- Testing
- Generative AI for electronic communication and disclosure
- Where
- United States
- Volunteers
- 1,454 people, healthy volunteers welcome
- Sponsor
- Duke University
Students of Undergraduate School of Nursing
Promoting Students' Development of Ultimate Concern Care Strategies
Teaching intervention
- Trial name
- NCT07532616
- Testing
- Teaching
- Where
- Taiwan
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Primary Caregiver Readiness for Care and Psychological Resilience in Palliative Care
Nurse-Led AI-Supported Psychosocial Support for Palliative Caregivers
Primary caregivers of palliative care patients assume responsibility for meeting the patient's needs, monitoring symptoms, maintaining care practices, and managing changing needs.
- Trial name
- NCT07799389
- Testing
- Nurse-Led, Generative AI-Supported Individualized Psychosocial Support Program, Routine Care and Information
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Shared Decision Making, Health Literacy
Designing a Large Language Model Architecture for Shared Decision Making and Informed Intentions
This study investigates a novel, agentic Large Language Model (LLM) architecture designed to facilitate Shared Decision-Making (SDM) in healthcare.
- Conditions
- Shared Decision Making, Health Literacy, Patient Participation, Artificial Intelligence
- Trial name
- DEONCAI3-1 (NCT07827924)
- Testing
- Agentic LLM Chatbot, Usual Care LLM Chatbot, IQWiG Standard Brochure
- Where
- Germany
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Harding Center for Risk Literacy
Procedural Pain Relief, Virtual Reality
AI-Generated Video Distraction Via Virtual Reality for Fear and Pain During Pediatric Circumcision
This randomized controlled trial evaluated the effect of artificial intelligence-generated video distraction delivered via virtual reality on procedural fear and pain in children undergoing circumcision.
- Conditions
- Procedural Pain Relief, Virtual Reality, Fear, Child
- Trial name
- NCT07824427
- Testing
- AI-Generated Video Distraction via Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Medical Education, Generative Artificial Intelligence
Teaching Medical Students to Verify AI-Generated Citation Hallucinations
Generative artificial intelligence (GenAI) tools are increasingly used by medical students for literature searching, scientific writing, and research. However, AI-generated citations may contain errors.
- Trial name
- SARA (NCT07844746)
- Testing
- SARA Citation-Verification Training, Responsible GenAI Education Intervention Description
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam Medical College
Anxiety and Fear
Trial of a Voice-Based Generative AI Emotional Support Companion
The investigators conduct a randomized controlled trial (RCT) to study an AI-based emotional support app. The focus in this paper is on two main areas: (1) changes in anxiety levels, and (2) safety.
- Trial name
- NCT07860034
- Testing
- The intervention was the AI-based emotional support app., Psychoeducational Material
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Palliative Care, Generative Artificial Intelligence
Patient Aid for Theory-Driven Health Communication (PATH): Translating Goal-Power Theory Into an Instrument and Generative AI Support for Palliative Care Communication
The goal of this clinical trial is to learn whether an artificial intelligence (AI)-supported communication tool can help improve communication between people receiving palliative care and their healthcare providers.
- Conditions
- Palliative Care, Generative Artificial Intelligence, Natural Language Processing (NLP)
- Trial name
- NCT07692711
- Testing
- NurseChat+
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Medical Education
AI-Generated and Rule-Based Individualized Feedback for Medical Students' Nephrology Learning
Medical education increasingly emphasizes individualized learning and formative assessment; however, providing timely and personalized feedback to students remains challenging because of limited faculty resources.
- Trial name
- AIFB-NR (NCT07871526)
- Testing
- AI-Generated Individualized Feedback, Rule-Based Individualized Feedback, No Individualized Feedback
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Dou Fulin
Shoulder Dystocia Training Using AI-supported Flipped Learning in Midwifery Education
Evalution of the Effectiveness of a Shoulder Dystocia Training Program Designed With Inverted Learning Supported by Generative Artificial Intelligence
With the ongoing digital transformation in health education, the importance of learner-centered and technology-integrated approaches has been increasing.
- Trial name
- NCT07514702
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Pregnancy, Prenatal Care
Comparing AI and Standard Pregnancy Chatbots
Many pregnant women in India use mobile phones to get health information. Nivi runs a free WhatsApp service called askNivi that answers questions about pregnancy and sends reminders about prenatal care visits.
- Conditions
- Pregnancy, Prenatal Care, Maternal Health
- Trial name
- NCT07883993
- Testing
- Scripted maternal health chatbot, MATRI retrieval-augmented maternal health chatbot
- Where
- India
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Nivi, Inc.
Clinical Decision Support
Artificial Intelligence (AI)-Initiated Clinical Decision Support in Hospitalist Practice
This study will evaluate the feasibility of using artificial intelligence (AI)-generated clinical decision support during routine inpatient hospital medicine care.
- Trial name
- NCT07889063
- Testing
- AI Clinical Decision Support: Automated EHR Data Retrieval, AI Clinical Decision Support: Admission H&P Note
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Nursing Education
AI-Assisted Child Health Podcast Education for Nursing Students
This randomized controlled study will evaluate the effect of developing and implementing artificial intelligence (AI)-assisted child health podcasts for parents on nursing students' attitudes toward clinical practice and learning…
- Trial name
- NCT07899541
- Testing
- AI-Assisted Child Health Podcast Development and Implementation
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Izmir University of Economics
Clinical Competence, Communication Skills
Generative AI Simulated Patients Versus Expert Demonstration Videos for Psychiatric Interview Training in Occupational Therapy Students
The goal of this study is to compare two methods for teaching psychiatric work-history interviewing to third-year occupational therapy students: practice with a generative AI simulated patient and an expert demonstration video.
- Conditions
- Clinical Competence, Communication Skills, Self Efficacy
- Trial name
- NCT07896525
- Testing
- Generative AI simulated patient, Expert demonstration video
- Where
- Taiwan
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cerebrovascular Disease
(Withdrawal) AI-Based Low-Dose 3D-DSA Reconstruction
If the participants agree to participate in this study, the participants will undergo two scans (classic 3D-DSA and PS-3D-DSA assisted scan) to compare the imaging effects of both.
- Trial name
- NCT06769867
- Testing
- PS-3D-DSA, classic 3D-DSA
- Where
- China
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Endodontic Diseases, Clinical Communication
Generative AI-Based Immersive Training for Endodontic Risk Disclosure and Informed Consent Among Dental Students
The objective of this prospective, parallel-group, 1:1 randomized controlled trial is to evaluate the effectiveness of a generative artificial intelligence (AI)-based immersive training program, utilizing the Gemini platform, in…
- Conditions
- Endodontic Diseases, Clinical Communication, Informed Consent
- Trial name
- GAI-ENDORDIC (NCT07731867)
- Testing
- Generative AI-Based Immersive Training, Conventional Case-Based Learning
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Primary Care Patients
AI to Create Accessible & Reliable Patient Education Materials
This study investigates the use of Generative AI (GAI) to support primary care practices in delivering accurate, accessible patient education.
- Trial name
- AI-CARE (NCT06997107)
- Testing
- Health promotional messages generated by Artificial Intelligence, Health promotional messages generated by humans
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hopital Montfort
Healthy Longevity
A Randomized Controlled Trial of a Multi-domain Smartphone Intervention Incorporating Generative AI for Healthy Older Adults
This study evaluates the efficacy of a smartphone-based multi-domain intervention designed to promote healthy aging and prevent cognitive decline in older adults.
- Trial name
- NCT07524478
- Testing
- Multidomain intervention, Control
- Where
- Japan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tatsuhiro Hisatsune